Photo by Amber Palmer

Find hotels near Mayo Clinic Florida, Jacksonville from AED 371

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 1,866 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (414)
"Excellent place to Stay!!"
The price is AED 580
AED 659 total
includes taxes & fees
24 Aug - 25 Aug
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

TownePlace Suites by Marriott Jacksonville East

3.0 star property
9.2 out of 10, Wonderful, (492)
"Close to 95, clean, friendly , lots of parking and close to beach. "
The price is AED 459
AED 521 total
includes taxes & fees
11 Aug - 12 Aug
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1006)
"I loved our stay"
The price is AED 434
AED 493 total
includes taxes & fees
24 Aug - 25 Aug
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very Good, (1003)
"Staff was great and the hotel had been totally refurbished. "
The price is AED 459
AED 522 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

TownePlace Suites by Marriott® Jacksonville Mayport

3.0 star property
10.0 out of 10, Exceptional, (14)
"New and very well kept property with pleasant staff."
The price is AED 466
AED 529 total
includes taxes & fees
10 Aug - 11 Aug
TownePlace Suites by Marriott® Jacksonville Mayport

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (352)
"Always the perfect stay"
The price is AED 552
AED 626 total
includes taxes & fees
11 Aug - 12 Aug
Salt Air Inn & Suites

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (287)
"Easy comfy convenient. "
The price is AED 694
AED 788 total
includes taxes & fees
6 Aug - 7 Aug
The Hotel Palms

Ponte Vedra Inn & Club

5.0 star property
9.4 out of 10, Exceptional, (802)
"Fabulous staff, one friendly greeting, the restaurants are good, the beach is lovely, breakfast outstanding"
The price is AED 1,319
AED 1,577 total
includes taxes & fees
11 Aug - 12 Aug
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (672)
"Excellent all around. Great amenities, very clean, and wonderful for families. "
The price is AED 1,319
AED 1,577 total
includes taxes & fees
1 Sep - 2 Sep
The Lodge and Club at Ponte Vedra Beach

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Clean hotel, would stay here again"
The price is AED 474
AED 538 total
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG

2.5 star property
9.4 out of 10, Exceptional, (1031)
"Really good place to stay for travel "
The price is AED 378
AED 429 total
includes taxes & fees
18 Aug - 19 Aug
Holiday Inn Express Jacksonville South Bartram Prk by IHG

Residence Inn by Marriott Jacksonville South/Bartram Park

3.0 star property
9.4 out of 10, Exceptional, (598)
"Rooms were clean and nice. "
The price is AED 393
AED 446 total
includes taxes & fees
17 Aug - 18 Aug
Residence Inn by Marriott Jacksonville South/Bartram Park

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1008)
"Great choice in hotel stay. "
The price is AED 448
AED 509 total
includes taxes & fees
24 Aug - 25 Aug
Holiday Inn Express Jacksonville Beach by IHG

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (2367)
"Loved our stay!"
The price is AED 509
AED 578 total
includes taxes & fees
1 Sep - 2 Sep
Hampton Inn Jacksonville Beach/Oceanfront

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
9.2 out of 10, Wonderful, (1010)
"Love this place!"
The price is AED 496
AED 563 total
includes taxes & fees
17 Aug - 18 Aug
Hyatt Place Jacksonville / St. Johns Town Center

Hotel Indigo Jacksonville-Deerwood Park by IHG

3.5 star property
9.2 out of 10, Wonderful, (1003)
"The food was excellent! "
The price is AED 448
AED 509 total
includes taxes & fees
1 Sep - 2 Sep
Hotel Indigo Jacksonville-Deerwood Park by IHG

Hampton Inn & Suites Jacksonville Deerwood Park

2.5 star property
9.2 out of 10, Wonderful, (1003)
"Great stay"
The price is AED 417
AED 473 total
includes taxes & fees
17 Aug - 18 Aug
Hampton Inn & Suites Jacksonville Deerwood Park

Courtyard by Marriott Jacksonville I-295/East Beltway

3.0 star property
9.2 out of 10, Wonderful, (559)
"The property was very nice. The food options were great. "
The price is AED 371
AED 421 total
includes taxes & fees
10 Aug - 11 Aug
Courtyard by Marriott Jacksonville I-295/East Beltway

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
9.0 out of 10, Wonderful, (1002)
"Very nice hotel "
The price is AED 621
AED 705 total
includes taxes & fees
1 Sep - 2 Sep
Four Points by Sheraton Jacksonville Beachfront

Best Western Oceanfront

2.5 star property
9.0 out of 10, Wonderful, (1010)
"Clean, nice property right at the beach with a very good breakfast "
The price is AED 485
AED 550 total
includes taxes & fees
11 Aug - 12 Aug
Best Western Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Mayo Clinic Florida Hotel Reviews

Hotels near Other Jacksonville Attractions

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 36 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 36 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.