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Compare 1,896 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Wyndham Garden Jacksonville
3.0 star property
7.0 out of 10, Good, (1434)
"Nice place. Good price. "
The price is AED 275
AED 302 total
includes taxes & fees
26 May - 27 May
Wyndham Garden Jacksonville
Exterior
Embassy Suites by Hilton Jacksonville Baymeadows
3.5 star property
8.2 out of 10, Very Good, (1003)
"It was very nice, quiet & clean. Staff that I encountered was very friendly and helpful. We stayed in the Atrium which was nice and quiet."
The price is AED 412
AED 460 total
includes taxes & fees
2 Jun - 3 Jun
Embassy Suites by Hilton Jacksonville Baymeadows
Exterior
Best Western Oceanfront
3.0 star property
8.8 out of 10, Excellent, (1005)
"Friendly staff, quiet location, near restaurants and right by the beach."
The price is AED 517
AED 576 total
includes taxes & fees
27 May - 28 May
Best Western Oceanfront
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Exterior
Four Points by Sheraton Jacksonville Beachfront
3.0 star property
9.0 out of 10, Wonderful, (1000)
"Great location and property "
The price is AED 779
AED 871 total
includes taxes & fees
22 May - 23 May
Four Points by Sheraton Jacksonville Beachfront
Breakfast meal
Holiday Inn Express Jacksonville Beach, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (1001)
"I liked that this was a smaller property. Rooms were clean. Breakfast was good. Personal were personable and helpful. "
The price is AED 435
AED 485 total
includes taxes & fees
9 Jun - 10 Jun
Holiday Inn Express Jacksonville Beach, an IHG Hotel
Room
Residence Inn by Marriott Jacksonville Butler Boulevard
3.0 star property
8.8 out of 10, Excellent, (747)
"Room was very nice! "
The price is AED 466
AED 522 total
includes taxes & fees
2 Jun - 3 Jun
Residence Inn by Marriott Jacksonville Butler Boulevard
Pool
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2.5 star property
8.0 out of 10, Very Good, (1001)
"It was an adequate stay. Neighborhood was not the best, but could also have been worse. Staff was ok. Cleanliness was good. "
The price is AED 316
AED 352 total
includes taxes & fees
18 Jun - 19 Jun
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
Exterior
Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel
3.5 star property
9.2 out of 10, Wonderful, (1002)
"Great location, friendly staff and accommodations "
The price is AED 438
AED 488 total
includes taxes & fees
27 May - 28 May
Hotel Indigo Jacksonville-Deerwood Park, an IHG Hotel
Exterior
WoodSpring Suites Jacksonville - South
2.5 star property
7.4 out of 10, Good, (285)
"STAFF VERY POLITE AND HELPFUL ROOMS VERY CLEAN"
The price is AED 253
AED 282 total
includes taxes & fees
20 May - 21 May
WoodSpring Suites Jacksonville - South
Exterior
Hampton Inn & Suites Jacksonville Deerwood Park
2.5 star property
9.2 out of 10, Wonderful, (1003)
"Quality suite, extremely friendly and courteous staff, excellent breakfast buffet and a quiet and laid back atmosphere. "
The price is AED 426
AED 472 total
includes taxes & fees
19 Jun - 20 Jun
Hampton Inn & Suites Jacksonville Deerwood Park
Exterior
Tru by Hilton Jacksonville South Mandarin
2.5 star property
8.8 out of 10, Excellent, (667)
"No coffee maker or ice bucket in rooms"
The price is AED 316
AED 351 total
includes taxes & fees
16 Jun - 17 Jun
Tru by Hilton Jacksonville South Mandarin
Room
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4 out of 10, Exceptional, (256)
"Cleanliness and transportation to and from the Mayo Clinic "
The price is AED 599
AED 667 total
includes taxes & fees
26 May - 27 May
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Exterior
Courtyard by Marriott Jacksonville Flagler Center
3.0 star property
8.8 out of 10, Excellent, (911)
"Staff was very accommodating, and the facility was well kept."
The price is AED 342
AED 382 total
includes taxes & fees
2 Jun - 3 Jun
Courtyard by Marriott Jacksonville Flagler Center
Lobby
Comfort Suites Baymeadows Near Butler Blvd
2.5 star property
7.8 out of 10, Good, (863)
"Great place "
The price is AED 340
AED 380 total
includes taxes & fees
2 Jun - 3 Jun
Comfort Suites Baymeadows Near Butler Blvd
Pool
Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
9.0 out of 10, Wonderful, (1003)
"Hotel is conveniently located near the interstate, but very quiet. My room was clean and comfortable. I would stay at this hotel again."
The price is AED 356
AED 398 total
includes taxes & fees
2 Jun - 3 Jun
Hampton Inn & Suites Jacksonville South - Bartram Park
Outdoor pool
Salt Air Inn & Suites
2.5 star property
9.8 out of 10, Exceptional, (165)
"Amazing customer service!"
The price is AED 468
AED 520 total
includes taxes & fees
21 May - 22 May
Salt Air Inn & Suites
Exterior
Quality Inn & Suites Jacksonville-Baymeadows
2.5 star property
5.6 out of 10, (1004)
"The roads leading into the property were landscaped with beautiful mature trees and bushes."
The price is AED 191
AED 216 total
includes taxes & fees
2 Jun - 3 Jun
Quality Inn & Suites Jacksonville-Baymeadows
Exterior
Hampton Inn Jacksonville-I-295 East/Baymeadows
2.5 star property
8.8 out of 10, Excellent, (1002)
"I was traveling to Key West and stayed at this hotel for the night but had to book an extra day due to illness. The staff was very accommodating. I want to point out employee "Q" at the front desk who was very polite, professional and helped me get on my way with ease. I will stay here again and recommend this hotel to anyone staying in the Jax area. The location was just of 295 allowed me to get back on I-95 quickly. "
The price is AED 359
AED 401 total
includes taxes & fees
16 Jun - 17 Jun
Hampton Inn Jacksonville-I-295 East/Baymeadows
Exterior
Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.2 out of 10, Wonderful, (590)
"The hotel staff are very friendly and care about your stay. The breakfast was good and the hotel room felt so homey "
The price is AED 554
AED 629 total
includes taxes & fees
29 May - 30 May
Tru By Hilton Jacksonville St Johns Town Center
Pool
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4 out of 10, Very Good, (640)
"NICE PROPERTY "
The price is AED 1,098
AED 1,247 total
includes taxes & fees
29 May - 30 May
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels near Other Jacksonville Attractions

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Adventure Landing

4/5(64 reviews)

Enjoy a fun-filled day at Adventure Landing during your trip to Jacksonville Beach. Stroll along the seaside or seek out the golf courses.

See properties
Adventure Landing

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 23 hotels and other accommodations you'll find within a mile.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 23 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

Recent reviews of Mayo Clinic Florida hotels
Expedia verified reviews

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

5/5 Excellent
"The hotel was extremely clean and well taken care of will definitely visit again."
A verified traveler stayed at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Posted 2 days ago
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area