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Our top choices for Mayo Clinic Florida hotels

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (158 reviews)
"Great place to stay"
United States
Judy
The price is AED 720
AED 817 total
includes taxes & fees
21 Mar - 22 Mar
Hilton Jacksonville At Mayo Clinic

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (582 reviews)
"Comfortable room, very nice staff. Great location."
United States
Andrew
The price is AED 444
AED 504 total
includes taxes & fees
16 Mar - 17 Mar
TownePlace Suites by Marriott Jacksonville East

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very Good, (765 reviews)
"Great location "
United States
Josiah Christine
The price is AED 657
AED 746 total
includes taxes & fees
27 Mar - 28 Mar
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (80 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is AED 511
AED 579 total
includes taxes & fees
1 Mar - 2 Mar
TownePlace Suites by Marriott® Jacksonville Mayport

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (539 reviews)
"Great place (and location)!"
United States
Dale
The price is AED 654
AED 742 total
includes taxes & fees
30 Mar - 31 Mar
Element Jacksonville Beach

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,002 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is AED 477
AED 542 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Hampton Inn & Suites Jacksonville Deerwood Park

Hampton Inn & Suites Jacksonville Deerwood Park
2.5 star property
Southside, 11.2 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (1,002 reviews)
"Great place to stay while in Jacksonville!"
United States
Willie
The price is AED 404
AED 458 total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn & Suites Jacksonville Deerwood Park

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 9.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
"Beautiful property and great staff "
United States
Andrew
The price is AED 496
AED 563 total
includes taxes & fees
20 Mar - 21 Mar
Sheraton Jacksonville Hotel

Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
3.5 star property
Southside, 10.8 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Great stay!"
United States
Margueritte
The price is AED 496
AED 563 total
includes taxes & fees
29 Mar - 30 Mar
Hotel Indigo Jacksonville-Deerwood Park by IHG

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,011 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is AED 441
AED 500 total
includes taxes & fees
22 Mar - 23 Mar
Best Western Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (642 reviews)
"The hotel was great! Very clean room and staff were very courteous and professional"
United States
Mike
The price is AED 716
AED 813 total
includes taxes & fees
22 Mar - 23 Mar
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,694 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is AED 559
AED 634 total
includes taxes & fees
2 Mar - 3 Mar
Margaritaville Jacksonville Beach

Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway
3.0 star property
Arlington, 13.2 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (650 reviews)
"The staff is friendly, and the room is clean."
United States
Wei-Kai
The price is AED 404
AED 459 total
includes taxes & fees
16 Mar - 17 Mar
Courtyard by Marriott Jacksonville I-295/East Beltway

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
Southside, 8.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (868 reviews)
"Clean room, professional staff, & good breakfast bar"
United States
Dwight
The price is AED 436
AED 495 total
includes taxes & fees
29 Mar - 30 Mar
Tru By Hilton Jacksonville St Johns Town Center

Residence Inn by Marriott Jacksonville South/Bartram Park

Residence Inn by Marriott Jacksonville South/Bartram Park
3.0 star property
17.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (643 reviews)
"Room was spotless and very nice"
United States
Theresa
The price is AED 459
AED 522 total
includes taxes & fees
16 Mar - 17 Mar
Residence Inn by Marriott Jacksonville South/Bartram Park

SpringHill Suites by Marriott Jacksonville Baymeadows

SpringHill Suites by Marriott Jacksonville Baymeadows
3.0 star property
Baymeadows, 12.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (898 reviews)
"great hotel"
United States
MARIA
The price is AED 411
AED 467 total
includes taxes & fees
22 Mar - 23 Mar
SpringHill Suites by Marriott Jacksonville Baymeadows

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,646 reviews)
"Everyone was friendly, kind and went out of their way to help with anything we needed. Great staff, great stay!"
United States
Barbara
The price is AED 631
AED 716 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville Beach/Oceanfront

Four Points by Sheraton Jacksonville Baymeadows

Four Points by Sheraton Jacksonville Baymeadows
3.0 star property
14.4 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,000 reviews)
"Nice and clean hotel for a short stay. "
United States
Amit
The price is AED 356
AED 404 total
includes taxes & fees
17 Mar - 18 Mar
Four Points by Sheraton Jacksonville Baymeadows

Candlewood Suites Jacksonville Southpoint by IHG

Candlewood Suites Jacksonville Southpoint by IHG
2.5 star property
15.4 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (363 reviews)
"Clean rooms, friendly staff"
United States
Alan
The price is AED 403
AED 457 total
includes taxes & fees
1 Mar - 2 Mar
Candlewood Suites Jacksonville Southpoint by IHG

Holiday Inn Express & Suites Jacksonville - Atlantic Beach by IHG

Holiday Inn Express & Suites Jacksonville - Atlantic Beach by IHG
2.5 star property
9 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,000 reviews)
"Our stay was great"
United States
Shawna
The price is AED 466
AED 529 total
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express & Suites Jacksonville - Atlantic Beach by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
158 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
582 reviews
View
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4
Very Good
765 reviews
View
Property amenity
TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.8
Exceptional
80 reviews
View
Property amenity
Element Jacksonville Beach
3.0 star property
9.6
Exceptional
539 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Hotels near other Mayo Clinic Florida attractions

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 47 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 47 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.
What can I see and do near Mayo Clinic Florida?
You can catch a show at Players by the Sea, SeaWalk Pavillion, and SeaWalk Pavillion. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.