Photo by Linda Cronan
Find all hotels by Motel 6 in Medical Center District, TX from AED 160
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Compare rooms and suites by Motel 6 in Medical Center District with rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Medical Center District Motel 6

Studio 6 San Antonio, TX - Airport
Studio 6 San Antonio, TX - Airport
6.2 out of 10, (1015)
The price is AED 243
AED 288 total
includes taxes & fees
25 Sep - 26 Sep

Motel 6 San Antonio, TX - Fiesta
Motel 6 San Antonio, TX - Fiesta
6.6 out of 10, (1019)
The price is AED 136
AED 160 total
includes taxes & fees
1 Oct - 2 Oct

Motel 6 San Antonio, TX - West SeaWorld
Motel 6 San Antonio, TX - West SeaWorld
6.2 out of 10, (1005)
The price is AED 156
AED 184 total
includes taxes & fees
25 Sep - 26 Sep

Motel 6 San Antonio, Tx - Frost Bank Center
Motel 6 San Antonio, Tx - Frost Bank Center
5.8 out of 10, (373)
The price is AED 145
AED 170 total
includes taxes & fees
5 Oct - 6 Oct

Motel 6 San Antonio, TX - Fiesta Trails
Motel 6 San Antonio, TX - Fiesta Trails
6.6 out of 10, (966)
The price is AED 169
AED 197 total
includes taxes & fees
25 Sep - 26 Sep

Motel 6 San Antonio, TX - Downtown - Alamo Dome
Motel 6 San Antonio, TX - Downtown - Alamo Dome
7.0 out of 10, Good, (1001)
The price is AED 195
AED 228 total
includes taxes & fees
25 Sep - 26 Sep

Motel 6 San Antonio, TX - Northwest Medical Center
Motel 6 San Antonio, TX - Northwest Medical Center
6.0 out of 10, (999)
The price is AED 161
AED 190 total
includes taxes & fees
8 Oct - 9 Oct

Motel 6 San Antonio, TX - Downtown - Market Square
Motel 6 San Antonio, TX - Downtown - Market Square
6.8 out of 10, (1006)
The price is AED 171
AED 203 total
includes taxes & fees
8 Oct - 9 Oct
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Medical Center District Hotel Reviews

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Medical Center District Hotels by Brand
Hotels in Medical Center District Neighborhoods
Hotels near popular San Antonio Attractions
- Hotels near USAA Corporate Office Headquarters
- Hotels near South Texas Medical Center
- Hotels near University of Texas Health and Science Center at San Antonio
- Hotels near CHRISTUS Santa Rosa Hospital - Medical Center
- Hotels near Oak Hills Country Club
- Hotels near The San Antonio Art Institute
- Hotels near River Walk
More Accommodation Types in Medical Center District
Explore more hotels
- Hotel Contessa
- Menger Hotel
- Hyatt Regency San Antonio Riverwalk
- Omni La Mansion del Rio
- The Westin San Antonio North
- The St. Anthony, A Luxury Collection Hotel, San Antonio
- Crockett Hotel
- La Quinta Inn & Suites by Wyndham San Antonio Downtown
- JW Marriott San Antonio Hill Country Resort & Spa
- InterContinental San Antonio Riverwalk by IHG
- Hyatt Place San Antonio - Riverwalk
- Kimpton Santo San Antonio - Riverwalk by IHG
- Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
- La Cantera Resort & Spa
- AC Hotel by Marriott San Antonio Riverwalk
- Grand Hyatt San Antonio River Walk
- Element San Antonio Riverwalk
- La Quinta Inn & Suites By Wyndham San Antonio At The Rim
- Spark by Hilton San Antonio Airport
- La Quinta Inn & Suites by Wyndham San Antonio Airport