Medical Center District Vacations

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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

4 out of top 10 points of interest in this area
4/5(9,525 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AED 364 per night from May 26 to May 27
AED 364
AED 431 total
includes taxes & fees
26 May - 27 May
8.4/10 Very Good! (2,533 reviews)
"Ok for a brief stay"

Reviewed on 22 May 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AED 320 per night from Jun 5 to Jun 6
AED 320
AED 381 total
includes taxes & fees
5 Jun - 6 Jun
8.2/10 Very Good! (1,001 reviews)
"This is one of the fancier hotels ive stayed at in a while. The loby was gorgeous as well as the very clean and open room. We had an issue shortly after arriving but the front office and maintenance were very quick and polite in making sure to solve it. Overall it was an amazing experience"

Reviewed on 22 May 2025

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
3 out of 5
9806 Interstate Hwy 10 W, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AED 367 per night from May 26 to May 27
AED 367
AED 434 total
includes taxes & fees
26 May - 27 May
9.2/10 Wonderful! (1,235 reviews)
"The location was very close to UTSA."

Reviewed on 23 May 2025

Drury Inn & Suites San Antonio Northwest Medical Center
See all 4,354 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Medical Center District

River Walk featuring night scenes and a river or creek

River Walk

4.5/5(7,278 reviews)

River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the lively festivals and shops in this walkable area.

River Walk
Six Flags Fiesta Texas

Six Flags Fiesta Texas

4.5/5(970 reviews)

Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the acclaimed theater scene and entertainment choices in this family-friendly area.

Six Flags Fiesta Texas
Lackland Air Force Base

Lackland Air Force Base

4.5/5(1,254 reviews)

Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area.

Lackland Air Force Base