Murphysboro Vacations

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Murphysboro Hotel Deals

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
Fully refundable
The price is AED 408 per night from Feb 22 to Feb 23
AED 408
AED 452 total
22 Feb - 23 Feb
includes taxes & fees
9.4/10 Exceptional! (522 reviews)
Friendly staff, wonderful breakfast, quiet. GREAT PLACE TO STAY!!

Reviewed on 8 February 2026

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite!

On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite!

Murphysboro IL
9.8/10 Exceptional! (16 reviews)
We had a lovely stay! The space was perfect for our family gathering. Our host was very responsive and welcoming. The home has a great location and we were able to enjoy some lovely hikes in the Shawnee and delicious BBQ in Murphysboro!

Reviewed on 29 December 2025

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On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite!
5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING

5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING

Murphysboro IL
10/10 Exceptional! (20 reviews)
Everything about this place was amazing. The host was quick to reply with any questions, everything was stocked and very clean! Highly recommend this place to anyone!

Reviewed on 14 January 2026

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5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING
See all 335 properties in Murphysboro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Murphysboro

General John A. Logan Museum

You can spend an afternoon exploring the galleries in General John A. Logan Museum during your trip to Murphysboro. You can enjoy the coffeehouses while in the area.

General John A. Logan Museum

Frequently asked questions

How do I find cheap flights to Murphysboro that have flexible change policies?
When it comes to traveling these days, flexibility is crucial. That's why we have a "No change fee" search function to help you track down flexible, low-priced tickets to Murphysboro. It's on the left-hand side of your screen just underneath the "Flexible change policies" subheading.
Which airlines fly to Murphysboro?
Arrange your fare with Contour Aviation and then start planning your Murphysboro itinerary. This top airline provides 52 flights per month to Williamson County Regional Airport (MWA), a major gateway.
How can I find cheap tickets to Murphysboro?
You'll always find an awesome deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred flight date, then check the flexible dates box above to see the cheapest prices for nearby days. was the lowest price for a flight to Murphysboro in the last seven days.
How much is a flight to Murphysboro?
You could have picked up a round-trip flight to Murphysboro from anywhere between and in the last seven days. For one-way journeys leaving from (), the lowest price during this time was .
What are the most popular airports to fly into in Murphysboro?
Jet into Williamson County Regional Airport (MWA) and sample everything that Murphysboro has to offer. As the region's main point of entry, around 52 flights land here every month.
When is the cheapest time to fly to Murphysboro?
If you'd rather spend your vacation savings exploring the delights of Murphysboro rather than on your trip there, jet off early in the week. The cheapest day to travel is usually Tuesday, with Monday a close second. With many folks traveling over the weekend, Saturday tends to have the most expensive airfares.
How much is a plane ticket to Murphysboro?
Ticket prices to Murphysboro ranged from to in the last seven days. Generally, the earlier you book the better the price.
What months are the cheapest to book a flight to Murphysboro?
A cheap month to secure a flight to Murphysboro is February, whereas prices are at a premium in December. Avoid this month if you're on a tight budget.