Find Resorts & Hotels with Spas in Murrells Inlet, SC

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Murrells Inlet Resorts & Hotels with Spas

Our top choices for Murrells Inlet hotels with a spa

Indoor pool, outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas
Marina Inn Grande Dunes Condos & Suites

Marina Inn Grande Dunes Condos & Suites

Marina Inn Grande Dunes Condos & Suites
5.0 star property
Myrtle Beach
9.6 out of 10, Exceptional, (66)
"Quality of entire facility was excellent. Staff was friendly. Only hiccup was checking in and the receptionist kept wiping her nose with her hand and touching my ID and bank card. "
United States
Annette
The price is AED 449
AED 584 total
includes taxes & fees
14 Dec - 15 Dec
Marina Inn Grande Dunes Condos & Suites
Couples treatment rooms, body treatments, hydrotherapy, aromatherapy
Anderson Ocean Club and Spa by Oceana Resorts

Anderson Ocean Club and Spa by Oceana Resorts

Anderson Ocean Club and Spa by Oceana Resorts
3.5 star property
Myrtle Beach
8.6 out of 10, Excellent, (2903)
"Everything was clean and comfortable, staff was friendly. "
United States
Jodie
The price is AED 413
AED 533 total
includes taxes & fees
9 Jan - 10 January 2026
Anderson Ocean Club and Spa by Oceana Resorts
Deluxe Studio, 2 Queen Beds, Oceanfront | Beach/ocean view
Dunes Village Resort

Dunes Village Resort

Dunes Village Resort
3.5 star property
Myrtle Beach
8.4 out of 10, Very Good, (3985)
"Convenient and would stay again."
United States
Tamara
Dunes Village Resort
Indoor pool, outdoor pool, open 7:00 AM to 11:00 PM, pool umbrellas
Marriott Myrtle Beach Resort & Spa at Grande Dunes

Marriott Myrtle Beach Resort & Spa at Grande Dunes

Marriott Myrtle Beach Resort & Spa at Grande Dunes
4.0 star property
Myrtle Beach
9.2 out of 10, Wonderful, (1005)
"Staff friendly, room clear, good food in the bar with excellent staff "
United States
Carolyn
The price is AED 511
AED 722 total
includes taxes & fees
13 Dec - 14 Dec
Marriott Myrtle Beach Resort & Spa at Grande Dunes
Sauna, body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton Myrtle Beach Resort

Hilton Myrtle Beach Resort

Hilton Myrtle Beach Resort
4.0 star property
Arcadian Shores
7.8 out of 10, Good, (1004)
"Fun stay"
United States
Peter Vincent
The price is AED 337
AED 528 total
includes taxes & fees
22 Dec - 23 Dec
Hilton Myrtle Beach Resort
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
Hilton Grand Vacations Club Anderson Ocean Myrtle Beach

Hilton Grand Vacations Club Anderson Ocean Myrtle Beach

Hilton Grand Vacations Club Anderson Ocean Myrtle Beach
3.5 star property
Myrtle Beach
9.0 out of 10, Wonderful, (954)
"Everything about this hotel was fantastic i def recommend to anyone"
United States
Kaiden
The price is AED 288
AED 388 total
includes taxes & fees
17 Dec - 18 Dec
Hilton Grand Vacations Club Anderson Ocean Myrtle Beach
Couples treatment rooms, body treatments, body scrubs, facials
Caribbean Resort & Villas

Caribbean Resort & Villas

Caribbean Resort & Villas
3.0 star property
Myrtle Beach
7.8 out of 10, Good, (626)
"Great room, very clean. Loved this hotel!"
United States
Willie
The price is AED 254
AED 436 total
includes taxes & fees
11 Dec - 12 Dec
Caribbean Resort & Villas
Body treatments, hot stone massages, facials, manicures and pedicures
Island Vista Resort

Island Vista Resort

Island Vista Resort
4.0 star property
Myrtle Beach
9.0 out of 10, Wonderful, (742)
"Very courteous staff; spotless room; beautiful ocean views from our room; plenty of parking spaces."
United States
Minka
Island Vista Resort
Premium bedding, in-room safe, desk, blackout drapes
Marina Inn At Grande Dunes

Marina Inn At Grande Dunes

Marina Inn At Grande Dunes
4.5 star property
Myrtle Beach
9.4 out of 10, Exceptional, (1749)
"I loved the clean rooms and the staff were so friendly and helpful."
United States
Ldavon
The price is AED 373
AED 484 total
includes taxes & fees
14 Dec - 15 Dec
Marina Inn At Grande Dunes
Sports facility
Embassy Suites by Hilton Myrtle Beach Oceanfront Resort

Embassy Suites by Hilton Myrtle Beach Oceanfront Resort

Embassy Suites by Hilton Myrtle Beach Oceanfront Resort
4.0 star property
Myrtle Beach
8.4 out of 10, Very Good, (1001)
"The staff was awesome and you have all the amenities you need in the hotel. "
United States
donna
The price is AED 385
AED 584 total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton Myrtle Beach Oceanfront Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Murrells Inlet Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in Murrells Inlet?
Forget the stress of everyday life and book yourself a lush spa hotel. Travelers like the beaches in Murrells Inlet. Be sure to pay a visit to the art galleries during your stay. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in Murrells Inlet?
Experience Murrells Inlet with a stop at Murrells Inlet Beach, Garden City Beach, and Pier at Garden City. If you have some spare time during your trip, you might want to check out Huntington Beach State Park and Brookgreen Gardens.
What is a Murrells Inlet spa hotel?
Spa hotels in Murrells Inlet provide lodging and have an on-site spa offering services such as massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.