The Best Family Hotels in Muscatine, IA from AED 266 in 2026

A river with docks, a bridge, and buildings in the background.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Muscatine Family Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Muscatine family-friendly hotels

Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Desk, iron/ironing board, WiFi (surcharge), alarm clocks

1. Best Western Muscatine / Pearl City Hotel

Muscatine

AED 336

AED 377 total

includes taxes & fees

6 Sep - 7 Sep

48-inch flat-screen TV with cable channels, TV

2. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

Muscatine

Family paradise on the Mississippi with indoor pool and kid-friendly dining—this hotel balances riverside fun and relaxation.

AED 621

AED 695 total

includes taxes & fees

26 Sep - 27 Sep

In-room safe, desk, cribs (free), rollaway beds (surcharge)

Room, Accessible | Bathroom | Combined shower/tub, deep soaking tub, rainfall showerhead

3. Super 8 by Wyndham Muscatine

Muscatine

Kids will love this hotel near Muscatine Aquatic Center, offering free cribs and breakfast just minutes from Mississippi River.

AED 237

AED 266 total

includes taxes & fees

7 Sep - 8 Sep

Suite, Multiple Beds, Non Smoking | Iron/ironing board, WiFi (free), bed sheets

Room, 1 King Bed, Non Smoking | Bathroom | Combined shower/tub, free toiletries, towels

4. Comfort Inn Muscatine near Hwy 61

Muscatine

AED 297

AED 332 total

includes taxes & fees

1 Oct - 2 Oct

Standard Room, 2 Queen Beds, Non Smoking | In-room safe, desk, iron/ironing board, WiFi (free)

5. Comfort Inn Walcott near Davenport

Walcott

AED 335

AED 375 total

includes taxes & fees

20 Sep - 21 Sep

3 restaurants; breakfast, lunch, and dinner served

6. Bally's Quad Cities

Rock Island

AED 463

AED 567 total

includes taxes & fees

1 Sep - 2 Sep

4 restaurants; breakfast, lunch, dinner, and brunch served

Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers

7. Riverside Casino & Golf Resort

Riverside

AED 562

AED 630 total

includes taxes & fees

3 Sep - 4 Sep

Room, 1 King Bed, Wheelchair Accessible, Non smoking | Premium bedding, pillowtop beds, in-room safe, desk

8. Quality Inn & Suites Eldridge Davenport North

Eldridge

AED 253

AED 284 total

includes taxes & fees

27 Sep - 28 Sep

View all properties

Choose what matters most at family-friendly hotels in Muscatine

Breakfast included

Pool

All-inclusive

4 stars

5 stars

Top Muscatine Hotel Reviews

Sleep Inn & Suites Davenport - Quad Cities

10/10 Excellent

"The hot tub wasn’t really working other than that everything was great"

Wyndham Moline on John Deere Commons

10/10 Excellent

"Very nice clean room close to event."

Comfort Inn Muscatine near Hwy 61

8/10 Good

".."

Best Western Muscatine / Pearl City Hotel

10/10 Excellent

"Great front desk staff and the room was very comfortable"

Frequently asked questions

What's Muscatine like for family-friendly vacations?

If you've been thinking about a vacation with your kids, Muscatine is a good choice. The entertainment, sporting events, and notable monuments are just a few things that make this an attractive place for families. Fly into Quad City Intl. Airport (MLI), which is located 27.9 mi (44.9 km) from the city center.

What's the best place to stay for a family trip to Muscatine?

Super 8 by Wyndham Muscatine is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel is another good choice for your family trip.

When's the best time to book a family-friendly vacation in Muscatine?

The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 30°F. The snowiest months in Muscatine are January, November, February, and December, with each month seeing an average of 7 inches of snowfall.

What's there to see and do with your family in Muscatine?

While you and the family are vacationing in Muscatine, you might want to check out some of the attractions here such as Muscatine Aquatic Center, Cedar River, and Mississippi River. Make sure you allow plenty of time for activities here like Wildcat Den State Park.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Muscatine Family Hotels

Our top choices for Muscatine family-friendly hotels

1. Best Western Muscatine / Pearl City Hotel