A cave with a bright light at the center and people swimming in the water.

Find Business Hotels in Northern Florida, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Northern Florida Business Hotels

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Northern Florida business-friendly hotels

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.
A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.
A hotel reception area with directional signs for elevators, floor 1, pool restrooms, and business center.
A modern lounge area with a flat-screen TV, a fireplace, teal and brown seating, patterned carpet, and a wall-mounted clock.

1. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
Gainesville
United States
Elizabeth
AED 364
AED 409 total
includes taxes & fees
13 Oct - 14 Oct
La Quinta by Wyndham Gainesville
A multi-story hotel with a central entrance, palm trees, and a clear sky.
A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.
A hotel room with a bed, a desk, a television, a sofa, and artwork on the wall.
A modern living room with a green sofa, a round coffee table, and a fireplace.

2. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
United States
sherry
AED 325
AED 365 total
includes taxes & fees
19 Oct - 20 Oct
Country Inn & Suites by Radisson, Gainesville, FL
A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.
A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.
A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.
A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.

3. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
United States
Adam
AED 386
AED 434 total
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Gainesville
A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.
A hotel room with a living area, kitchenette, and a large mirror.
A hotel hallway with carpeted floors, doors on both sides, and overhead lighting.
A hotel room with a kitchenette, a bed, a desk with a chair, and a bathroom.

4. Hampton Inn Gainesville

Hampton Inn Gainesville
Gainesville
United States
Ross
AED 318
AED 358 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Gainesville
A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.
Outdoor lounge chairs with metal frames and fabric seats, arranged in rows.
A Sleep Inn & Suites building with a clear entrance, a covered waiting area, and a parking lot.
A hotel room with two beige armchairs, a small side table, a glass display cabinet with sports memorabilia, a mounted flat-screen TV, and a door with a wooden frame.

5. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville
United States
Diego
AED 293
AED 351 total
includes taxes & fees
1 Nov - 2 Nov
Sleep Inn & Suites University/Shands
Lobby sitting area
A hotel with a modern facade, a covered entrance, and a palm tree in front.
A modern dining area with tables and chairs, a kitchen counter, and a sign reading "höm cooking".
A modern building with a gray facade, a large window, and a landscaped area with a crocodile sculpture.

6. HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
Gainesville
United States
Cassandra
AED 283
AED 318 total
includes taxes & fees
18 Oct - 19 Oct
HOM Hotel Gainesville, SureStay Collection by Best Western
A modern interior with a staircase, a seating area, and a colorful abstract wall design.
A modern bar area with a marble countertop, bar stools, and pendant lighting.
A rooftop pool area with lounge chairs, a small table, and a fire pit.
A spacious lobby with modern furniture, large windows, and a colorful abstract wall.

7. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
United States
Claire
AED 393
AED 442 total
includes taxes & fees
10 Nov - 11 Nov
Hyatt Place Gainesville Downtown
A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.
A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.
A hotel room with a bed, a desk, a chair, a sofa, and a window.
A modern hotel lobby with a reception desk, seating area with chairs and ottomans, a large artwork, and a corridor leading to other rooms.

8. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
United States
Samantha
AED 307
AED 357 total
includes taxes & fees
1 Nov - 2 Nov
Comfort Suites Gainesville near University
A hotel room with a bed, a nightstand, and a wall-mounted light fixture.
A compact hotel room with a television, a sofa, a chair, and a small table.
A modern indoor dining area with tables and chairs, large windows, and a view of the outdoors.
A modern building with a curved glass facade, outdoor seating area, and a grassy courtyard.

9. Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida
Gainesville
United States
Diane
AED 559
AED 629 total
includes taxes & fees
18 Oct - 19 Oct
Hotel Eleo at the University of Florida
Exterior
A grey sofa with three cushions in different colors, a white cushion, and a book on the left side.
A hotel room with two beds, a desk with a flat-screen TV, a sofa, and a large window offering a view of the outdoors.
A modern kitchen with a central island, stainless steel appliances, and a pendant light.

10. Hyatt House Destin

Hyatt House Destin
Destin
United States
Ackim
AED 342
AED 386 total
includes taxes & fees
1 Nov - 2 Nov
Hyatt House Destin
View all properties

Top Northern Florida Hotel Reviews

Equus Inn Ocala

Equus Inn Ocala

8/10 Good
"For the price point this was a great stay."
Carla 1-night trip
Posted 8 hours ago
Equus Inn Ocala
Hilton Daytona Beach Oceanfront Resort

Hilton Daytona Beach Oceanfront Resort

10/10 Excellent
"The staff was great, the room was clean and guest services were quick to meet our needs."
Diane 3-night trip
Posted 15 hours ago
Hilton Daytona Beach Oceanfront Resort

Explore a world of travel with Expedia