A cave with a bright light at the center and people swimming in the water.

Find Business Hotels in Northern Florida, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Northern Florida Business Hotels

Tonight
19 Oct - 20 Oct
Tomorrow
20 Oct - 21 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Northern Florida business-friendly hotels

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.
A hotel lobby with a seating area featuring sofas and armchairs, a central coffee table, and a flat-screen TV mounted on the wall.
A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.
A hotel reception area with directional signs for elevators, floor 1, pool restrooms, and business center.

1. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
Gainesville
United States
Edwin
AED 364
AED 409 total
includes taxes & fees
20 Oct - 21 Oct
La Quinta by Wyndham Gainesville
A multi-story hotel with a central entrance, palm trees, and a clear sky.
A modern living room with a green sofa, a round coffee table, and a fireplace.
A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.
A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.

2. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
United States
Tricia
AED 325
AED 365 total
includes taxes & fees
25 Oct - 26 Oct
Country Inn & Suites by Radisson, Gainesville, FL
A person pouring a drink into a glass.
A hotel room with a sofa, a desk, a chair, a bed, a TV, and a dining table with a glass and cookie.
A modern gym with treadmills, exercise bikes, and weight equipment.
A spacious hotel lobby with a checkered carpet, wooden paneling, and two large chandeliers.

3. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
Gainesville
United States
Courtney
AED 371
AED 422 total
includes taxes & fees
22 Oct - 23 Oct
Hotel Indigo Gainesville-Celebration Pointe by IHG
A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.
A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.
A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.
A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.

4. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
United States
Adam
AED 389
AED 438 total
includes taxes & fees
26 Oct - 27 Oct
Drury Inn & Suites Gainesville
A Sleep Inn & Suites building with a sign, surrounded by palm trees and parked cars.
Fitness facility
Exterior
Pool

5. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville
United States
Diego
AED 293
AED 351 total
includes taxes & fees
8 Nov - 9 Nov
Sleep Inn & Suites University/Shands
Lobby sitting area
A hotel with a modern facade, a covered entrance, and a palm tree in front.
A modern building with a gray facade, a large window, and a landscaped area with a crocodile sculpture.
A modern dining area with tables and chairs, a kitchen counter, and a sign reading "höm cooking".

6. HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
Gainesville
Canada
Jenna
AED 266
AED 299 total
includes taxes & fees
25 Oct - 26 Oct
HOM Hotel Gainesville, SureStay Collection by Best Western
A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.
A hotel hallway with carpeted floors, doors on both sides, and overhead lighting.
A hotel room with a living area, kitchenette, and a large mirror.
A hotel room with a kitchenette, a bed, a desk with a chair, and a bathroom.

7. Hampton Inn Gainesville

Hampton Inn Gainesville
Gainesville
United States
Ross
AED 371
AED 417 total
includes taxes & fees
29 Oct - 30 Oct
Hampton Inn Gainesville
A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.
A hotel room with a bed, a desk, a chair, a sofa, and a window.
A fire pit area surrounded by stone tiles, with a metal fence in the background.
A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.

8. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
United States
Samantha
AED 309
AED 359 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Suites Gainesville near University
A modern interior with a staircase, a seating area, and a colorful abstract wall design.
A spacious lobby with modern furniture, large windows, and a colorful abstract wall.
A rooftop pool area with lounge chairs, a small table, and a fire pit.
A modern hotel lobby with a round table featuring two drinks, a sofa, and a colorful wall art piece.

9. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
United States
Brendon
AED 364
AED 409 total
includes taxes & fees
17 Nov - 18 Nov
Hyatt Place Gainesville Downtown
A Holiday Inn Express & Suites building with a parking lot, a flag, and a well-lit entrance.
A modern hotel lobby with a sofa, chairs, a dining area, and a television.
A clean, well-organized snack and beverage area with shelves stocked with various snacks and drinks, and a refrigerator with beverages.
A beach with a fishing rod on the sand.

10. HOLIDAY INN EXPRESS & SUITES GULF BREEZE - PENSACOLA AREA by IHG

HOLIDAY INN EXPRESS & SUITES GULF BREEZE - PENSACOLA AREA by IHG
Gulf Breeze
United States
Tori
AED 378
AED 424 total
includes taxes & fees
16 Nov - 17 Nov
HOLIDAY INN EXPRESS & SUITES GULF BREEZE - PENSACOLA AREA by IHG
View all properties

Top Northern Florida Hotel Reviews

Equus Inn Ocala

Equus Inn Ocala

10/10 Excellent
"⭐⭐⭐⭐⭐ This is our second time staying. The hotel was very clean and well-maintained. The room was spotless, the bathroom was clean, and the entire property was neat and comfortable. Housekeeping did an excellent job, and the cleanliness made my stay even more enjoyable. Highly recommend this hotel for its excellent cleanliness and comfort!"
Analyn 1-night trip
Posted 3 hours ago
Equus Inn Ocala
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

10/10 Excellent
"Clean room staff great and beautiful view"
Marvyn 2-night trip
Posted 19 hours ago
The Island Resort at Fort Walton Beach

Explore a world of travel with Expedia