Nuevo Santiago Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AED 148 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Nuevo Santiago Vacation Packages

Nuevo Santiago Hotel Deals

Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is AED 312 per night from Nov 12 to Nov 13
AED 312
AED 343 total
12 Nov - 13 Nov
includes taxes & fees
8.8/10 Excellent! (533 reviews)
Great room, great food and great price

Reviewed on 29 October 2025

Hotel Mykonos Panama
Hotel Galería

Hotel Galería

3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Fully refundableReserve now, pay when you stay
The price is AED 235 per night from Nov 12 to Nov 13
AED 235
AED 259 total
12 Nov - 13 Nov
includes taxes & fees
8.2/10 Very Good! (199 reviews)
Perfect overnight stop
We stayed over night on our way home from Panama City. I used the pool, very clean and refreshing. Everything was clean and comfortable. I couldn’t get hot water in the shower, but my son had no problem. The breakfast was excellent.

Reviewed on 21 June 2025

Hotel Galería
Hotel Plaza

Hotel Plaza

3 out of 5
Interamericana, Nuevo Santiago, Veraguas
It's a 35 $ a night hotel !!

Reviewed on 21 August 2023

Get rates
Hotel Plaza
See all 12 properties in Nuevo Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How do I find cheap flights to Nuevo Santiago that have flexible change policies?
Search for your affordable flights to Nuevo Santiago, then check the "No change fee" box directly under the "Flexible change policies" heading. It's that easy. We appreciate that travel plans change and flexibility matters, so you can book with confidence with Expedia.
How can I find cheap tickets to Nuevo Santiago?
An excellent strategy for scoring cheap airfares is to be flexible with your travel dates. Begin with searching for your flight to Nuevo Santiago, then click on the "flexible dates" box to see prices for nearby days. Another handy tip? Book well ahead of time. For an idea of costs, was the best price for a flight to Nuevo Santiago in the last seven days.
How much is a flight to Nuevo Santiago?
In the last seven days, round-trip flights to Nuevo Santiago sold for as little as and reached a maximum cost of . For one-way fares taking off from (), the lowest price during this time was .
When is the cheapest time to fly to Nuevo Santiago?
Fly out on a Tuesday to boost your chances of scoring the cheapest fare to Nuevo Santiago. Mondays are usually the next most affordable day to take off. Saturday is typically the costliest day to fly anywhere.
How much is a plane ticket to Nuevo Santiago?
Seats to Nuevo Santiago ranged from to in the last seven days. Normally, the sooner you book the better the price.
What months are the cheapest to book a flight to Nuevo Santiago?
February is the best month to bag a terrific deal to Nuevo Santiago. Keep in mind that the most expensive time to book a seat in the U.S. Isn't during the peak of summer, but in December.