O Brien, FL

Travel Guide

Photo by Dr__Vlad
Photo by Dr__Vlad
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD, Alachua, FL
The price is AED 430 per night from Nov 23 to Nov 24
AED 430
AED 483 total
23 Nov - 24 Nov
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
We stopped here on our way to the Florida Keys and it was a nice stay. No complaints!

Reviewed on 20 October 2025

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr, Lake City, FL
The price is AED 296 per night from Nov 2 to Nov 3
AED 296
AED 333 total
2 Nov - 3 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,036 reviews)
Friendly staff , comfortable beds and decent. Breakfast .

Reviewed on 24 October 2025

Best Western Plus Lake City
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE, Lake City, FL
The price is AED 347 per night from Oct 26 to Oct 27
AED 347
AED 391 total
26 Oct - 27 Oct
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,025 reviews)
Clean room

Reviewed on 22 October 2025

La Quinta Inn & Suite by Wyndham Lake City
See all 334 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien
Book a stay at this beach vacation home in O Brien. Enjoy free WiFi, a beach locale, and a fitness center. Popular attractions Wes Skiles Peacock Springs State ...
9.8/10 Exceptional! (27 reviews)
This was an absolutely delightful house on the water. Plenty of room for the kids to run, it didn't feel sketchy with the river nearby (if you're anxious like me and worried about kids near a river, there's a decent land barrier), tons of stuff to do at the house and nearby, gorgeous area and great ...

Reviewed on 12 October 2025

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

O'Brien
Stay at this vacation home in O Brien. Enjoy a garden, laundry facilities, and patios. Popular attractions Wes Skiles Peacock Springs State Park and Telford ...
9.4/10 Exceptional! (59 reviews)
A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!

Reviewed on 1 September 2025

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337, High Springs, FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
9.8/10 Exceptional! (129 reviews)
Such a happy experience and makes having a pet even more fun. Can wait to do it again!

Reviewed on 23 October 2025

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
See all properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.