Palermo Historical Center, a neighborhood in Palermo, is home to La Serenissima Hotel. Teatro Massimo and Palermo Cathedral are notable landmarks, and the area's natural beauty can be seen at Mondello Beach. Madonna Annunciate and Palermo Botanical Garden are also worth visiting. Visit our Palermo travel guide
Via dei Cassari 24, Palermo, PA, 90133
What's nearby
Palermo Harbour
1 min walk - 0.1 km
Via Vittorio Emanuele
1 min walk - 0.1 km
Via Roma
3 min walk - 0.3 km
Teatro Massimo
10 min walk - 0.9 km
Quattro Canti
7 min walk - 0.6 km
Getting around
Imperatore Federico Station
6 min drive
Palermo Central Station
13 min walk
Punta Raisi Airport (PMO)
48 min drive
Restaurants
Buatta Cucina Popolana
2 min walk
Nni Franco U Vastiddaru
2 min walk
Arancinando Food Factory
1 min walk
Sardina PastaBar
1 min walk
dal Barone
3 min walk
About this property
La Serenissima Hotel
Hotel near Palermo Harbour
Close to Via Roma and Teatro Massimo, La Serenissima Hotel provides a terrace, a bar, and more. Guests can connect to free in-room WiFi.
Other perks at this hotel include:
Buffet breakfast (surcharge), an elevator, and a 24-hour front desk
Smoke-free premises
Guest reviews give top marks for the helpful staff
Room features
All guestrooms at La Serenissima Hotel have thoughtful touches such as laptop-friendly workspaces and air conditioning, as well as amenities like free WiFi and safes.
Other amenities include:
Bathrooms with rainfall showers and bidets
Balconies, free infant beds, and heating
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No, only service animals are welcome at the property.
How much does it cost to stay at La Serenissima Hotel?
As of 24 October 2026, prices found for a 1-night stay for 2 adults at La Serenissima Hotel on 8 November 2026 start from AED 278, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
This property doesn't offer parking.
What time is check-in at La Serenissima Hotel?
Check-in start time: 1:30 PM; Check-in end time: 11:00 PM. Late check-in is available during limited hours.
What time is check-out at La Serenissima Hotel?
Check-out is at 10:30 AM.
Where is La Serenissima Hotel located?
Located in Palermo Historical Center, this hotel is within a 5-minute walk of Palermo Harbour and Via Roma. Teatro Massimo and Palermo Cathedral are also within 15 minutes. Giachery Station is 27 minutes by foot and Palermo Central Station is 13 minutes.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
La Serenissima Hotel Reviews
8.6
Excellent
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.
Staff were lovely but the room was very dirty (hairs everywhere in the bathroom and the bedroom itself with dirt marks on the wall by the bin). The shower head holder was broken both in terms of height and direction, it totally fell down so you had to hold it yourself to take a shower and the cold tap stays lukewarm at all times.
Aircon worked and it was not noisy at all on a Saturday night which was great and the location was fantastic. Appreciate this hotel is a bit of a cheap and cheerful find and we only stayed for one night so it didn’t spoil our trip or anything, but at a minimum the shower should be functional and the room should be clean.
⭐️ Beautiful hotel in the heart of Palermo — but think twice about driving!
The hotel itself is beautiful and perfectly located in Palermo’s historic centre, with easy access to the nightlife, sights and cruise port. Our room was huge, with a separate bedroom and living/family-room area, and had everything we needed. We would absolutely stay here again.
My biggest caution is arriving with a rental car. The hotel is within the ZTL, and Google Maps struggled to navigate us through the extremely narrow and restricted streets. Make sure you carefully read the hotel’s instructions and provide your licence plate and driver information in advance.
We were given contact information for several garages, but had difficulty getting responses and initially received very little assistance from the hotel. After I expressed my frustration through Expedia, the hotel stepped in and arranged the parking for us, which I appreciated. I do think the arrival, ZTL and parking process could be explained more clearly and proactively.
The area is lively and noisy at night, but that’s also part of the charm of staying right in historic Palermo. Bring earplugs if you’re a light sleeper, then step outside and enjoy the nightlife!
Overall, a wonderful hotel in a fantastic location. I would happily stay again—but next time I’d arrive by taxi rather than rental car! 🇮🇹
what a find!!!!!!!!spotless and excellent rooms ,good breakfast but best of all staff who are very helpful and welcoming. I have stayed at Italian 5 star hotels who could learn from this one--thanks
we are a group of well travelled 'older' guys who enjoy short breaks --100% satisfied with this hotel and indeed Palermo
The location was perfect for walking about with lots cute little shops and restaurants. The breakfast menu was great with a helpful staff. It felt a lot like Bourbon Street in Louisiana during the weekend with the street lined with happy people until the early morning. I ended up joining in my last night and had a fantastic time. The room was nice with a cute balcony looking over the cobblestone streets. I would definitely stay there again.
Stayed 3 nights in Oct 2025
Verified review
8/10 Good
Hayden
16 July 2025
Liked: Cleanliness, staff & service
Great location, lots of lively options for food and drink. Bed is a little hard and shower very little but staff were very friendly and helpful. Let me check in at 10am because the the room was ready which was fantastic
The hotel iand staff are great. The pubs in the area when they are open Wednesday, Friday, Saturday and Sunday are very loud and even with the windows closed you better be a heavy sleeper or you will have to wait until 5am to get some sleep. Other than that the staff is there when needed breakfast was good.
Beautifully clean room and common area. Conveniently located to great restaurants, fish market and shopping. Excellent staff service and breakfast service for 10£.
Very comfortable room. The street side room is above restaurants so noise volumes are a bit louder but i was so tired that it did not keep me up.
This location is in the heart of the entertainment District. Great access to bars, clubs and restaurants with a wide variety of each. Can get a little loud if you want to go to bed early but other than that a great location.
I liked the location of the property.
The hotel was very dated. They were very rigid, I was specifically told that if i was not at the reception by check out time then I will charged extra.
Stay elsewhere, there are plenty of hotels around the area.
Stayed 1 night in Jul 2025
Verified review
2/10 Terrible
Yuri
6 November 2025
Disliked: Amenities
I could list numerous issues with both the hotel and its service. For example, throughout our entire two-week stay, the internet was not working due to unexplained reasons, and the hotel offered no compensation or attempt to address the inconvenience. The only positive aspect of this place is its location.
Stayed 14 nights in Oct 2025
Verified review
6/10 Okay
Morgan
12 March 2025
Liked: Staff & service
Cheap rate, dated room, friendly service, terrible bed. You get what you pay for.
Stayed 1 night in Mar 2025
Verified review
6/10 Okay
C
15 June 2024
Liked: Staff & service
The hotel is in average condition: there is no web access in the rooms and only one AC (of 2) units worked. Otherwise, it is nicely located in the historic center of Palermo with walking distance to all attractions.
The staff was awesome and very helpful.
Street noise a bit loud.
Shower door needs attention. Step down in extra room needs signage. Room 103.
Can be very dangerous
The property itself was nice and conveniently located. I just felt there were too many rules, sort of like being held under the watchful eye of catholic nuns and priests. There are several other hotels in the area, so I would recommend choosing another hotel with less restrictions.
The staff are very friendly and helpful. It’s a great location for exploring the Centro Storico, but it does get noisy on weekend nights.
The building is well-maintained and clean.
We stayed in an attic room. It is a good size, with a nice terrace, but in a portion if the room, where the desk is, the ceiling is so low you will hit your head. The showers are very small (barely bigger than a slender person) and the bathroom is tight.
Overall an excellent hotel. The glaring issue with me was the filthy entrance carpet and área immediately outside the front door. It gives one the impression that the place is poorly maintained on the inside, which is not the case. Just not a very welcoming appearance. Our shower wand was leaking, so the maids need to pay more attention to the conditions in the room. Very well designed interiors and great location . Certainly would stay again!
Stayed 3 nights in Oct 2023
Verified review
6/10 Okay
Dr. Stefan
11 August 2024
Liked: Cleanliness, staff & service
Nice and spacious rooms wirh large bed - but if you stay here at the weekend, be sure that you won't sleep more than two hours! A noisy lane with lots of pubs - and they don't think about stopping open-air music before 5 a m.! The explication of the hotel owners that they cannot change that is completely unsatisfying. Maybe the wrong place to run a hotel.
Absolute great location-lots of food and drink choices right outside the door. Reasonable walking distance to major landmarks and close access to Uber or taxi.