Panacea, FL Vacation Homes

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Our top choices for Panacea vacation homes

1. Panacea Treehouse⭐️ Waterfront-Boat Friendly

Panacea

kind h.

AED 1,201 total

includes taxes & fees

4 Aug - 5 Aug

2. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

Panacea

william C.

AED 1,784 total

includes taxes & fees

5 Aug - 6 Aug

3. Point & Paddle Waterfront Retreat @Alligator Point

Alligator Point

Scott A.

AED 1,789 total

includes taxes & fees

3 Aug - 4 Aug

4. The Best Beach-Front House “Get-A-Way” in Florida

Panacea

Juliet H.

AED 2,496 total

includes taxes & fees

31 Aug - 1 Sep

5. NEW - St. Teresa Beach Escape w/ Private Beach Acc

Lanark Village

Debra M.

AED 2,514 total

includes taxes & fees

3 Aug - 4 Aug

6. Bill's Bay Breeze- relax on the porch and enjoy the view!

Alligator Point

Lee Ann K.

AED 1,660 total

includes taxes & fees

4 Aug - 5 Aug

7. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

Alligator Point

V G.

AED 8,040 total

includes taxes & fees

16 Aug - 17 Aug

8. Relax at Shell Point Beach! Bring your boat to park at the dock.

Crawfordville

Anonymous traveler

AED 1,863 total

includes taxes & fees

20 Aug - 21 Aug

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Top Panacea Hotel Reviews

Your Private Slice of the Forgotten Coast—Steps to Sand

10/10 Excellent

"We enjoyed our stay here so much and we were very sad to go! The place was AMAZING! It is family friendly and pet friendly. The beach and ocean are right where you can see them and easy to access. Utilize the outdoor shower to helo with sand tracking in and out. The laundry room is located down stairs next to the outdoor shower. Bring extra big spray!!! The flies bite pretty good right before a rain. We aren't a super wealthy family so our main chunk of money went to the house so we cooked everything at the house. The trash service runs once a week so it was a tight squeeze for 6 people for a whole week but we made it work! There are beautiful views and breathtaking sunrises and you can sit on the deck or in the living room and see it because of the massive windows in the living room! When the tide goes out at night you can go explore and find all kinds of creatures in thw shallows. Wear sunscreen! And we made sure to have hats on and that helped alot! Overall we highly recommend this place and it is private as well. It was well worth the money and it was a wonderful experience!"

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

10/10 Excellent

"Ohana shack is a luxury vacation home that you don’t want to miss out on! We have already scheduled a return next year.Our whole family had a wonderful time in the house and at the secluded beach. We may have seen 4 people on the beach the whole week. The guys enjoyed fishing off the beach, and crabbing. We felt very safe in the secluded beach area, that was literally a few steps from the house, for our little 2, almost 3, year old granddaughters splashing in the surf.All of the rooms were well done. The beds were so comfortable. The pictures can’t do any of it justice. The room with the king sized bed and 4 built in bunks were perfect for our son’s family. The girls slept on the bottom bunks. Their brother and cousin on the top bunks. My husband and I had the master bedroom across the hall. Our daughter and her husband and their daughter and best friend had the two suites on the lower floor.The kitchen was well equipped. We even invested in it by adding a waffle iron and a few other things. The appliances were top notch!The living area had very comfortable seating. We even looked up the two chairs to see if we could get some.There is a fridge/freezer in the very lower level to hold extra stuff you may need during your stay, to keep you from having to run into town for supplies. You may as well buy extra ice, because you will need it. There are also beach chairs. We even added a couple more to the collection. The hot tub is enormous. The elevator is awesome!"

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

10/10 Excellent

"Charming beach house just steps away from the beach. The beach was quiet which is a great alternative to crowded beaches. Robin was very responsive and helpful. Would love to come back!"

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"We had a wonderful stay at this beautiful home on the bay in Panacea! The waterfront views were absolutely stunning, and it was so peaceful to sit outside and enjoy the scenery. The house was clean, comfortable, and had everything we needed for a relaxing getaway. It was exactly as described and made for the perfect place to unwind. The host was great to work with and made the entire experience easy from start to finish. We would definitely stay here again and highly recommend this property to anyone looking for a peaceful escape with incredible bay views."

Secluded Florida Beach Bungalow BEST OF BOTH WORLDS BEACH TIME & FISHING TIME!!

10/10 Excellent

"We love the Spotted Grouper! We have returned for several years. The cottage is cozy with so many amenities—washer/dryer, beach wagon, great supply of towels. Booking is so easy and Sheree is a marvelous host."

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

10/10 Excellent

"Our family of 12 had an amazing stay! The house is absolutely beautiful, thoughtfully decorated, and had everything we could have needed. We spent most of our time relaxing on the screened-in porch enjoying the incredible ocean views.The kitchen was one of the best-stocked we’ve ever seen, and we really appreciated all of the beach gear, chairs, toys, and wagon that were available. The huge DVD collection was also a lifesaver during the tropical storm while our kids were stuck inside.The host was fantastic. Communication was excellent from start to finish, with quick responses and helpful information that made our stay even easier.The location is definitely secluded, which was exactly what we were looking for. We highly recommend The Salty Donkey and Angelo’s for eating out, and My Way Seafood Market for fresh seafood to cook at the house."

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Check prices for these dates

Our top choices for Panacea vacation homes

1. Panacea Treehouse⭐️ Waterfront-Boat Friendly

2. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

3. Point & Paddle Waterfront Retreat @Alligator Point

4. The Best Beach-Front House “Get-A-Way” in Florida

5. NEW - St. Teresa Beach Escape w/ Private Beach Acc

6. Bill's Bay Breeze- relax on the porch and enjoy the view!

7. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

8. Relax at Shell Point Beach! Bring your boat to park at the dock.

9. Dragonfly on the Canal with golf cart included beginning 7/12/26

10. Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching

11. McMahon's Tail-Waggin' Retreat in the Heart of Crawfordville with AC, Fenced.

12. The Oyster Bed- Riverwalk Cottages Unit 204 B

13. The Sand Dollar - Riverwalk Cottages Unit 204 A

14. The Blue Crab at Riverwalk Cottages Unit 202B

Find vacation rentals that suit your style

Top Panacea Hotel Reviews

Your Private Slice of the Forgotten Coast—Steps to Sand

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

Best deal at Alligator Point

The Panacea Motel

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

40% off for monthly rate, Views of the gulf & bay, 4 porches w/panoramic views.

Hideaway Beach Cottage on waterfront with amazing views.

Secluded Florida Beach Bungalow BEST OF BOTH WORLDS BEACH TIME & FISHING TIME!!

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Search Vacation Homes in Panacea

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Panacea vacation homes

1. Panacea Treehouse⭐️ Waterfront-Boat Friendly

2. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

3. Point & Paddle Waterfront Retreat @Alligator Point

4. The Best Beach-Front House “Get-A-Way” in Florida

5. NEW - St. Teresa Beach Escape w/ Private Beach Acc

6. Bill's Bay Breeze- relax on the porch and enjoy the view!

7. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

8. Relax at Shell Point Beach! Bring your boat to park at the dock.

9. Dragonfly on the Canal with golf cart included beginning 7/12/26

10. Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching

11. McMahon's Tail-Waggin' Retreat in the Heart of Crawfordville with AC, Fenced.

12. The Oyster Bed- Riverwalk Cottages Unit 204 B

13. The Sand Dollar - Riverwalk Cottages Unit 204 A

14. The Blue Crab at Riverwalk Cottages Unit 202B

Find vacation rentals that suit your style

Top Panacea Hotel Reviews

Your Private Slice of the Forgotten Coast—Steps to Sand