A calm lake with a wooden pier extending into the water, surrounded by tall grasses.

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Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for Panacea vacation homes

A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

1. Panacea Treehouse- Quiet-Waterfront Pet Friendly Fall Fishing Retreat

Panacea Treehouse- Quiet-Waterfront Pet Friendly Fall Fishing Retreat
Panacea
9.8 out of 10, Exceptional, (28 reviews)
"Great place to stay while fishing"
United States
Benjamin S.
Panacea Treehouse- Quiet-Waterfront Pet Friendly Fall Fishing Retreat
A porch with wicker chairs and a small table, overlooking a lake and trees.

2. Point & Paddle Waterfront Retreat @Alligator Point

Point & Paddle Waterfront Retreat @Alligator Point
Alligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
United States
Scott A.
The price is AED 698
AED 1,708 total
includes taxes & fees
9 Nov - 10 Nov
Point & Paddle Waterfront Retreat @Alligator Point
A modern building with a covered porch, a clear view of the water, and a well-maintained lawn.

3. Winter Escape on Ochlockonee Bay: Private Beach, Dock Fishing, Kayaks, Sunsets

Winter Escape on Ochlockonee Bay: Private Beach, Dock Fishing, Kayaks, Sunsets
Panacea
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful view and beautiful home. Enjoyed making memories at this place"
United States
Toby H.
The price is AED 798
AED 1,761 total
includes taxes & fees
1 Nov - 2 Nov
Winter Escape on Ochlockonee Bay: Private Beach, Dock Fishing, Kayaks, Sunsets
A wooden deck with a table and chairs, a patterned sofa, and an umbrella.

4. 3BR, 2BA Beach Front Peaceful Retreat Recently Renovated with Private Boardwalk

3BR, 2BA Beach Front Peaceful Retreat Recently Renovated with Private Boardwalk
Alligator Point
9.6 out of 10, Exceptional, (10 reviews)
"We had a very restful and relaxing time. The beach is very quiet and only saw a few people on the beach in our 5 days that we were there. The beds were comfy and clean! The kitchen was well stocked. The house needs some TLC but was clean."
United States
Pam m.
3BR, 2BA Beach Front Peaceful Retreat Recently Renovated with Private Boardwalk
A wooden deck with wicker chairs and a long table, overlooking a beach and ocean.

5. The Best Beach-Front House “Get-A-Way” in Florida

The Best Beach-Front House “Get-A-Way” in Florida
Panacea
10.0 out of 10, Exceptional, (101 reviews)
"Wonderful place on the beach. My sister and I had a great time here. I especially love that the beach is dog-friendly!"
United States
Lisa R.
The price is AED 1,055
AED 2,349 total
includes taxes & fees
1 Nov - 2 Nov
The Best Beach-Front House “Get-A-Way” in Florida
A modern kitchen with a central island, bar stools, stainless steel appliances, and a view of the outdoors.

6. Breezy Home w/ Grills, Pool & Beach Access!

Breezy Home w/ Grills, Pool & Beach Access!
Sopchoppy
10.0 out of 10, Exceptional, (28 reviews)
"We enjoyed the home and felt absolute comfort. We enjoyed direct beach access, bikes rides, and the pool access. We visited Alligator Point, Wakulla Springs, and St. George Island while there."
United States
Crystal
The price is AED 804
AED 2,026 total
includes taxes & fees
24 Nov - 25 Nov
Breezy Home w/ Grills, Pool & Beach Access!
A two-story house with a balcony on each floor, a front porch with steps, and a clear sky.

7. NEW - St. Teresa Beach Escape w/ Private Beach Acc

NEW - St. Teresa Beach Escape w/ Private Beach Acc
Lanark Village
10.0 out of 10, Exceptional, (2 reviews)
"This house was very comfortable, beds, pillows, towels, sofa, etc. Quiet, peaceful, serene setting. Close proximity to beach and the pool was an added bonus!Thank you for a very enjoyable stay!"
United States
Debra M.
The price is AED 1,153
AED 2,748 total
includes taxes & fees
1 Nov - 2 Nov
NEW - St. Teresa Beach Escape w/ Private Beach Acc
A wooden deck with outdoor furniture, overlooking a beach and ocean.

8. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
Panacea
9.6 out of 10, Exceptional, (95 reviews)
"Charming beach house just steps away from the beach. The beach was quiet which is a great alternative to crowded beaches. Robin was very responsive and helpful. Would love to come back!"
United States
cyle w.
The price is AED 1,316
AED 2,901 total
includes taxes & fees
23 Nov - 24 Nov
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
A wooden deck with a table and chairs, overlooking a beach.

9. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Alligator Point
10.0 out of 10, Exceptional, (131 reviews)
"The house was perfect for our family, especially my mom who has trouble walking. The elevator worked perfectly, the boardwalk was short and close to the ocean. She and my dad loved sitting on the deck and watching us all on the beach. Communication was great, including updates on the tropical storm. We would definitely recommend this rental. We hope to stay again!"
United States
Lori M.
The price is AED 3,306
AED 8,246 total
includes taxes & fees
1 Nov - 2 Nov
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
A riverside view from a covered deck with wooden docks and a bench.

10. Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching

Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching
Crawfordville
10.0 out of 10, Exceptional, (58 reviews)
"Nice and relaxing"
United States
chad c.
The price is AED 645
AED 1,055 total
includes taxes & fees
1 Nov - 2 Nov
Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching
A modern kitchen with white cabinets, a granite countertop, and pendant lighting.

11. Dragonfly on the Canal Golf cart included!

Dragonfly on the Canal Golf cart included!
Crawfordville
10.0 out of 10, Exceptional, (62 reviews)
"Very welcoming community and lived up to its name with being fully dragonfly & beach themed. Wish we could have fully enjoyed the outside amenities, but the weather had other plans."
United States
Allison
The price is AED 479
AED 1,127 total
includes taxes & fees
3 Nov - 4 Nov
Dragonfly on the Canal Golf cart included!
A bedroom with a bed, a ceiling fan, a nightstand with a lamp, and a window with curtains.

12. The Oyster Bed- Riverwalk Cottages Unit 204 B

The Oyster Bed- Riverwalk Cottages Unit 204 B
Carrabelle
9.8 out of 10, Exceptional, (51 reviews)
"Loved that the property was pet friendly! Enjoyed the stay here as it is close proximity to shopping,dining and sight-seeing!"
United States
Tom K.
The Oyster Bed- Riverwalk Cottages Unit 204 B
A living room with a glass-top table surrounded by wicker chairs, a black sofa, and a coffee table with decorative items.

13. The Sand Dollar - Riverwalk Cottages Unit 204 A

The Sand Dollar - Riverwalk Cottages Unit 204 A
Carrabelle
10.0 out of 10, Exceptional, (31 reviews)
"Great location, clean cute cottage. Very comfortable."
United States
Debi P.
The Sand Dollar - Riverwalk Cottages Unit 204 A
A bedroom with a chandelier, a bed, a dresser, a chair, and a desk.

14. Wedding & Event Residence Sopchoppy 5 bedrooms/Honeymoon Suite

Wedding & Event Residence Sopchoppy 5 bedrooms/Honeymoon Suite
Sopchoppy
The price is AED 18,181
AED 21,183 total
includes taxes & fees
14 Nov - 15 Nov
Wedding & Event Residence Sopchoppy 5 bedrooms/Honeymoon Suite
A living room with two grey armchairs, a teal cabinet, a glass coffee table with wooden legs, and a flat-screen TV on the wall.

15. FISHERMAN'S PARADISE!! Cozy home 2 minutes to the Gulf

FISHERMAN'S PARADISE!! Cozy home 2 minutes to the Gulf
Carrabelle
9.4 out of 10, Exceptional, (3 reviews)
"Everything was as described. We had a great stay."
United States
Jared R.
FISHERMAN'S PARADISE!! Cozy home 2 minutes to the Gulf
A two-story house with a covered porch, a staircase, and a view of the surrounding greenery.

16. Beach/Marina/Walking trails and more…

Beach/Marina/Walking trails and more…
Carrabelle
10.0 out of 10, Exceptional, (4 reviews)
"Nice house, pet friendly, easy parking highly recommend. Thanks for a great vacation!"
United States
Edward H.
The price is AED 496
AED 1,647 total
includes taxes & fees
12 Nov - 13 Nov
Beach/Marina/Walking trails and more…
A hotel room with a bed, a sofa, a dining area with wicker chairs, and a glass table.

17. The Blue Crab at Riverwalk Cottages Unit 202B

The Blue Crab at Riverwalk Cottages Unit 202B
Carrabelle
9.6 out of 10, Exceptional, (15 reviews)
"We enjoyed staying here."
United States
Tammy P.
The Blue Crab at Riverwalk Cottages Unit 202B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panacea Hotel Reviews

Great sunrise view from dining area and decks. Easy beach access.

Great sunrise view from dining area and decks. Easy beach access.

10/10 Excellent
"We really enjoyed our stay. It was a perfect location. A few steps from the beach. Beach house was perfect. We will be back again."
Lynne W. 5-night trip
Posted 2 days ago
Great sunrise view from dining area and decks. Easy beach access.