Find Resorts & Hotels with Spas in Panama City, FL

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels

    Be picky

    Search almost a million properties worldwide

Check availability on Panama City Resorts & Hotels with Spas

This weekend
Next weekend

Top Panama City Resorts & Hotels with Spas

Holiday Inn Resort Panama City Beach by IHG
3.5 star property
9.2 out of 10, Wonderful, (1218)
"Very nice hotel! "
United States
Suzan
The price is AED 415
AED 649 total
includes taxes & fees
10 Nov - 11 Nov
Holiday Inn Resort Panama City Beach by IHG
Embassy Suites by Hilton Panama City Beach Resort
3.5 star property
8.6 out of 10, Excellent, (1092)
"Had a great stay "
United States
Jason
The price is AED 372
AED 512 total
includes taxes & fees
11 Nov - 12 Nov
Embassy Suites by Hilton Panama City Beach Resort
Enjoy amazing ocean views in this 3rd floor condo with same level parking.
9.2 out of 10, Wonderful, (57)
"Walked into a beautiful and clean condo. Had everything we needed. Location was wonderful. "
United States
Sommer W.
The price is AED 420
AED 1,164 total
includes taxes & fees
1 Nov - 2 Nov
Enjoy amazing ocean views in this 3rd floor condo with same level parking.
Carillon Beach Inn by Vacasa
3.5 star property
8.0 out of 10, Very Good, (80)
"The bed was super comfy. Short walk to the beach. Nice pools. The property is so nice to walk around. The coffee and wine shop was excellent!!"
United States
Robert
The price is AED 851
AED 1,163 total
includes taxes & fees
1 Nov - 2 Nov
Carillon Beach Inn by Vacasa
BEACHFRONT CONDO NOW ACCEPTING RENTALS!!
9.2 out of 10, Wonderful, (123)
"We enjoyed staying at this unit. It was perfect for our family and is accurately described on VRBO. The condo could be fixed up a little. There were bulbs not working, light fixtures not working, and some normal wear and tear over time. But I think this was a fair price that made up for it."
United States
Lindsay B.
The price is AED 331
AED 1,588 total
includes taxes & fees
29 Oct - 30 Oct
BEACHFRONT CONDO NOW ACCEPTING RENTALS!!
The Pearl Hotel
4.0 star property
9.4 out of 10, Exceptional, (186)
"Very beautiful hotel with great attentive staff steps away from the beach. "
United States
Madelyn
The price is AED 1,732
AED 2,166 total
includes taxes & fees
12 Nov - 13 Nov
The Pearl Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in Panama City?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers love the array of shops in Panama City. Discover the beaches and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Panama City?
Enjoy all that Panama City has to offer and visit Panama City Marina, Panama City Mall, and Port Panama City. If you have spare time during your trip, you might want to make a stop at St. Andrews State Park and Naval Support Activity Panama City.
What is a Panama City spa hotel?
Spa hotels in Panama City provide lodging and have an on-site spa which offers services including facials as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.