San Francisco

Panama City

A bridge over a body of water with several boats.
A city skyline with a flag, a river, and a park.
A coastal cityscape with high-rise buildings and a beach.
A cityscape with a prominent twisted skyscraper in the center, surrounded by various other buildings and a distant mountain range.
A beach with a large driftwood piece, calm water, and a few people in the distance.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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San Francisco Hotel Deals

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is AED 437 per night from Nov 16 to Nov 17
AED 437
AED 481 total
16 Nov - 17 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,432 reviews)
"The reception staff was very nice and helpful Kitchen staff 10/10 The buildings is very well maintained the property is spotless Rooms are cleaned on a daily basis,clean linen 10/10 My only challenge was the toilet there was a slight odor other than that it exceeded my expectations Proximity to the ..."

Reviewed on 12 November 2026

Ramada Plaza by Wyndham Panama Punta Pacifica
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is AED 553 per night from Nov 18 to Nov 19
AED 553
AED 609 total
18 Nov - 19 Nov
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (1,875 reviews)
"-Good value for money -Good breakfast buffet -Spacious suites -Nice hotel but needs refurbishing and lots of maintenance I would stay there again."

Reviewed on 12 November 2026

Megapolis Hotel Panamá
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is AED 347 per night from Dec 13 to Dec 14
AED 347
AED 384 total
13 Dec - 14 Dec
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,741 reviews)
"Breakfast was excellent."

Reviewed on 10 November 2026

Decapolis Hotel Panama City
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is AED 479 per night from Nov 21 to Nov 22
AED 479
AED 527 total
21 Nov - 22 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,014 reviews)
"Everything"

Reviewed on 9 November 2026

Aloft by Marriott Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is AED 551 per night from Nov 22 to Nov 23
AED 551
AED 606 total
22 Nov - 23 Nov
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,146 reviews)
"Long check in lines and front desk staff was not so friendly."

Reviewed on 12 November 2026

Las Americas Golden Tower Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is AED 482 per night from Nov 28 to Nov 29
AED 482
AED 530 total
28 Nov - 29 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Courtyard by Marriott Panama Multiplaza Mall
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.

San Francisco

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