Santa Ana

Panama City

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.

Stay near popular Santa Ana attractions


Santa Ana Hotel Deals

Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo

3 out of 5
Plaza De Santa Ana Panama City Provincia di Panama
The price is AED 127 per night from Nov 13 to Nov 14
AED 127
AED 140 total
13 Nov - 14 Nov
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
7.6/10 Good! (31 reviews)
"El lugar es acorde a lo q se paga, esta donde termina el casco viejo y empieza un barrio feo"

Reviewed on 5 November 2026

Hotel Caracas - Casco Viejo
Casco View Life Residences

Casco View Life Residences

4 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is AED 262 per night from Nov 22 to Nov 23
AED 262
AED 402 total
22 Nov - 23 Nov
includes taxes & fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...
9/10 Wonderful! (114 reviews)
"The staff was very friendly and helpful which made our stay very pleasant and enjoyable."

Reviewed on 31 October 2026

Casco View Life Residences
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is AED 485 per night from Dec 1 to Dec 2
AED 485
AED 533 total
1 Dec - 2 Dec
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Riu Plaza Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is AED 475 per night from Nov 18 to Nov 19
AED 475
AED 522 total
18 Nov - 19 Nov
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,018 reviews)
"Muy mala la atención, no fueron amables, no accedieron a mi petición de una habitación en 1 piso por estar con niños pequeños, mala distribución de toallas, papel, etc"

Reviewed on 10 November 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is AED 514 per night from Nov 26 to Nov 27
AED 514
AED 590 total
26 Nov - 27 Nov
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,802 reviews)
"I liked the fact that it was welcoming and the staff was very patient and helpful. The other part was that the door key was why turned the lights on that was cool"

Reviewed on 12 November 2026

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is AED 964 per night from Dec 1 to Dec 2
AED 964
AED 964 total
1 Dec - 2 Dec
includes taxes & fees
Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall ...
Dreams Playa Bonita Panama - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.



Santa Ana

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