A sunset over a calm lake with red autumn leaves on the right.

Poplar Bluff Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
28 Aug - 30 Aug
In two months
9 Oct - 11 Oct
In three months
6 Nov - 8 Nov
In four months
4 Dec - 6 Dec

Our top choices for Poplar Bluff vacation rentals

Exterior detail

1. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
8.8 out of 10, Excellent, (15 reviews)
"House was great. Will definitely be back."
United States
Anonymous traveler
The price is AED 422
AED 1,058 total
includes taxes & fees
15 Aug - 16 Aug
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Coffee/tea maker, fridge, microwave, oven

2. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
The price is AED 477
AED 591 total
includes taxes & fees
12 Aug - 13 Aug
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Front of property

3. Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
9.0 out of 10, Wonderful, (4 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is AED 281
AED 296 total
includes taxes & fees
12 Aug - 13 Aug
Lake Wappapello
Property grounds

4. Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (99 reviews)
"Gorgeous property, wonderful hosts. Would love to visit again "
United States
Anonymous traveler
The price is AED 386
AED 481 total
includes taxes & fees
12 Aug - 13 Aug
Get Away Acres 1/2 mile off highway 60 extra sanitized
Interior

5. Cozy hobby farm cabin under the stars!

Cozy hobby farm cabin under the stars!
Greenville
10.0 out of 10, Exceptional, (8 reviews)
"Easy check in, very quiet, very calming and relaxing. Overall great stay and great property manager. "
United States
Wyatt S.
The price is AED 272
AED 439 total
includes taxes & fees
9 Sep - 10 Sep
Cozy hobby farm cabin under the stars!
Property grounds

6. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
10.0 out of 10, Exceptional, (1 review)
"Very cozy"
United States
Shea E.
The price is AED 526
AED 1,009 total
includes taxes & fees
18 Aug - 19 Aug
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Exterior

7. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
8.0 out of 10, Very Good, (36 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
The price is AED 393
AED 800 total
includes taxes & fees
19 Aug - 20 Aug
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Exterior

8. Secluded Private Beautiful Cabin in Mill Spring MO

Secluded Private Beautiful Cabin in Mill Spring MO
Mill Spring
10.0 out of 10, Exceptional, (3 reviews)
"This was the perfect little place! The host was amazing and left us muffins and a welcome note. It was a super cute little place!"
United States
Sara A.
The price is AED 465
AED 566 total
includes taxes & fees
16 Aug - 17 Aug
Secluded Private Beautiful Cabin in Mill Spring MO
Smart TV, books

9. Doc's Cottage - A-Frame in Piggott, AR

Doc's Cottage - A-Frame in Piggott, AR
Piggott
10.0 out of 10, Exceptional, (14 reviews)
"Excellent! Will stay again!"
United States
Michael M.
The price is AED 485
AED 851 total
includes taxes & fees
12 Aug - 13 Aug
Doc's Cottage - A-Frame in Piggott, AR
Coffee/tea maker, fridge, microwave, oven

10. The Morning Glory - Country Cottage

The Morning Glory - Country Cottage
Piggott
10.0 out of 10, Exceptional, (8 reviews)
"House was clean and had everything we needed for a comfortable stay!"
United States
Justin C.
The price is AED 485
AED 898 total
includes taxes & fees
12 Aug - 13 Aug
The Morning Glory - Country Cottage
Coffee/tea maker, fridge, microwave, oven

11. Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
The price is AED 679
AED 1,369 total
includes taxes & fees
12 Aug - 13 Aug
Hunting / Fishing Cabin at Lake Wappapello
1 bedroom

12. 2 Queen Beds|Non-Smoking

2 Queen Beds|Non-Smoking
Malden MO
The price is AED 327
AED 401 total
includes taxes & fees
1 Sep - 2 Sep
2 Queen Beds|Non-Smoking
Interior

13. Secluded Shop-House Retreat - Walk to Heritage Park!

Secluded Shop-House Retreat - Walk to Heritage Park!
Piggott
The price is AED 547
AED 815 total
includes taxes & fees
11 Sep - 12 Sep
Secluded Shop-House Retreat - Walk to Heritage Park!
Coffee/tea maker, fridge, microwave, oven

14. Scotty's sunny spot

Scotty's sunny spot
Doniphan
10.0 out of 10, Exceptional, (10 reviews)
"Beautiful home, comfortable, and convenient to everything"
United States
Mickey S.
The price is AED 613
AED 1,532 total
includes taxes & fees
8 Sep - 9 Sep
Scotty's sunny spot
Property grounds

15. Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing

Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing
Grandin
10.0 out of 10, Exceptional, (22 reviews)
"The lodge was a wonderful place for the ten adults and two small children in our family to gather and spend a long weekend! We had everything we needed in the lodge. "
United States
Mitchell W.
The price is AED 1,484
AED 2,673 total
includes taxes & fees
12 Aug - 13 Aug
Rustic Lodge Near Current River: Pond + Fire pit + Trails + Pickleball + Fishing
Lobby

16. King Bed|Non-Smoking

King Bed|Non-Smoking
Malden MO
The price is AED 295
AED 363 total
includes taxes & fees
1 Sep - 2 Sep
King Bed|Non-Smoking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Poplar Bluff Hotel Reviews

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent
"The rooms were clean and the breakfast was great!"
Arsenia 3-night trip
Posted 10 hours ago
Fairfield Inn & Suites by Marriott Poplar Bluff

Frequently asked questions

Can I find a vacation rental in Poplar Bluff?

Yes, we offer vacation rentals in Poplar Bluff near Mo-Ark Regional Railroad Museum, or you can select a secluded option if you want a relaxing stay. Our travelers say Poplar Bluff has a good selection of restaurants. Make sure you have time to check out the water park and waterfalls during your trip.

What are some of the best vacation rentals that Poplar Bluff has to offer?

Home Sweet Home, Spacious Sunroom & Fun Deck!: This highly rated vacation home rental in Poplar Bluff offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Our travelers also rate 40-Acre Poplar Bluff Nature Lovers Paradise! as a favorite home for rent in Poplar Bluff.

How many vacation rentals are there in Poplar Bluff?

Choose from 7 Expedia vacation rentals in Poplar Bluff for a memorable vacation.

What can I see and do in Poplar Bluff?

Cultural attractions include Mo-Ark Regional Railroad Museum and Margaret Harwell Art Museum, whereas Mark Twain National Forest is one spot to enjoy nature. Other places in town to visit include Black River Coliseum and North Main Street Historic District.

What are vacation rentals like in Poplar Bluff?

Vacation rentals are private properties you can book for a short or long stay in Poplar Bluff. Vacation rentals offer extras like laundry facilities and kitchens so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for family gatherings.