A beach with waves and a sky with clouds.

Search Vacation Homes in Port Saint Lucie

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
9 Oct - 11 Oct
In two months
20 Nov - 22 Nov
In three months
18 Dec - 20 Dec
In four months
15 Jan - 17 Jan

Our top choices for Port Saint Lucie vacation homes

Smart TV, DVD player

1. Cozy Oasis

Cozy Oasis
Port St. Lucie
9.0 out of 10, Wonderful, (90 reviews)
"The house was great"
United States
Carlos
The price is AED 496
AED 1,194 total
includes taxes & fees
12 Oct - 13 Oct
Cozy Oasis
Indoor spa tub

2. Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!

Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
Port St. Lucie
9.8 out of 10, Exceptional, (8 reviews)
"Friendly host, great room and amazing pool and hot tub. "
United States
Matthew B.
The price is AED 419
AED 645 total
includes taxes & fees
26 Sep - 27 Sep
Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
2 bedrooms, iron/ironing board, WiFi, bed sheets

3. Charming 2-bedroom guest house with Pool in Port St. Lucie

Charming 2-bedroom guest house with Pool in Port St. Lucie
Port St. Lucie
The price is AED 327
AED 666 total
includes taxes & fees
29 Sep - 30 Sep
Charming 2-bedroom guest house with Pool in Port St. Lucie
1 bedroom, WiFi, bed sheets

4. Waterfront Canal Retreat w/ Private Entrance

Waterfront Canal Retreat w/ Private Entrance
Oak Hammock
The price is AED 349
AED 526 total
includes taxes & fees
29 Sep - 30 Sep
Waterfront Canal Retreat w/ Private Entrance
Beach

5. Lush | Tropical | Modern Home w/ Heated Pool & Spa

Lush | Tropical | Modern Home w/ Heated Pool & Spa
Sandhill Crossing
10.0 out of 10, Exceptional, (28 reviews)
"Loved the house and the pool area!"
United States
Brandy
The price is AED 519
AED 1,850 total
includes taxes & fees
28 Sep - 29 Sep
Lush | Tropical | Modern Home w/ Heated Pool & Spa
1 bedroom, WiFi, bed sheets

6. La Dolce Vita Studio

La Dolce Vita Studio
Port St. Lucie
9.6 out of 10, Exceptional, (11 reviews)
"Great location.Room is excellent with all basic needs.Will book again."
United States
james h.
The price is AED 367
AED 1,032 total
includes taxes & fees
26 Sep - 27 Sep
La Dolce Vita Studio
Iron/ironing board, internet, bed sheets

7. Salt Coast Pool Side Retreat

Salt Coast Pool Side Retreat
Floresta Gardens
Salt Coast Pool Side Retreat
Interior

8. Cozy 2-bedroom house in nice Port St. Lucie with AC

Cozy 2-bedroom house in nice Port St. Lucie with AC
Port St. Lucie
10.0 out of 10, Exceptional, (2 reviews)
"Communication was great! House was nice and clean apon arrival will be booking again"
United States
Shantalae J.
The price is AED 327
AED 776 total
includes taxes & fees
29 Sep - 30 Sep
Cozy 2-bedroom house in nice Port St. Lucie with AC
Coffee/tea maker, fridge, microwave, oven

9. BR Tropical Oasis in Port St Lucie

BR Tropical Oasis in Port St Lucie
Port Saint Lucie
8.6 out of 10, Excellent, (4 reviews)
"We are a construction company that had workers in from out of town and the place was great "
United States
Sabrina B.
The price is AED 382
AED 1,851 total
includes taxes & fees
27 Sep - 28 Sep
BR Tropical Oasis in Port St Lucie
House, 3 Bedrooms, Private Pool, Garden View | Pool | Outdoor pool

10. Port St. Lucie Poolside Oasis

Port St. Lucie Poolside Oasis
2.0 star property
Port Saint Lucie
The price is AED 592
AED 1,782 total
includes taxes & fees
1 Oct - 2 Oct
Port St. Lucie Poolside Oasis
Smart TV, fireplace

11. Comfortable 3BR Home Base in a Prime Location

Comfortable 3BR Home Base in a Prime Location
Northport Village
Comfortable 3BR Home Base in a Prime Location
Exterior

12. Private Pool Home Near Beach & Golf in FL

Private Pool Home Near Beach & Golf in FL
Palm Trails
8.0 out of 10, Very good, (1 review)
"Communication was clear and accurate. Pool and house were very nice. The kitchen wasn’t stocked well if you wanted to cook at the house. Very few pots, pans, etc."
United States
Tim A.
The price is AED 294
AED 1,330 total
includes taxes & fees
5 Oct - 6 Oct
Private Pool Home Near Beach & Golf in FL
Interior

13. Bohemian Bungalow

Bohemian Bungalow
Port St. Lucie
10.0 out of 10, Exceptional, (8 reviews)
"This was the perfect place to stay. The house had everything we could need and Lisa was wonderful!"
United States
Sydney M.
The price is AED 494
AED 1,284 total
includes taxes & fees
2 Oct - 3 Oct
Bohemian Bungalow
Interior

14. Waterfront Tiki Oasis - Dock & Ocean Access

Waterfront Tiki Oasis - Dock & Ocean Access
River Park
10.0 out of 10, Exceptional, (1 review)
"Great place to stay. Clean and a perfect location. We will definitely stay here again. "
United States
Shaun B.
The price is AED 496
AED 1,459 total
includes taxes & fees
2 Oct - 3 Oct
Waterfront Tiki Oasis - Dock & Ocean Access
Sun loungers, beach towels

15. Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!

Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!
Port St. Lucie
10.0 out of 10, Exceptional, (5 reviews)
"Muy acogedor , excelente para pasar en familia , con todas las condiciones 👌"
United States
Jeiny
The price is AED 566
AED 1,552 total
includes taxes & fees
2 Oct - 3 Oct
Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!
Coffee/tea maker, fridge, microwave, oven

16. CHEERFUL 3 BEDROOM HOME

CHEERFUL 3 BEDROOM HOME
Port St. Lucie
8.4 out of 10, Very good, (16 reviews)
"The location was very convenient and they accept pets! "
United States
CATHERINE M.
The price is AED 367
AED 1,124 total
includes taxes & fees
16 Oct - 17 Oct
CHEERFUL 3 BEDROOM HOME
4 bedrooms, iron/ironing board, WiFi, bed sheets

17. Lovely 4-bedroom house in Port St Lucie

Lovely 4-bedroom house in Port St Lucie
Gatlin Pines
The price is AED 592
AED 1,474 total
includes taxes & fees
27 Sep - 28 Sep
Lovely 4-bedroom house in Port St Lucie
Exterior

18. Villa Blue - Private Heated Pool - Sleeps 8

Villa Blue - Private Heated Pool - Sleeps 8
Sandpiper Bay
10.0 out of 10, Exceptional, (23 reviews)
"Amazing place! So many fun things to do and was so beautiful on the inside!"
United States
Victoria K.
The price is AED 705
AED 1,580 total
includes taxes & fees
27 Sep - 28 Sep
Villa Blue - Private Heated Pool - Sleeps 8
Outdoor pool, a heated pool

19. golf view villa near beach

golf view villa near beach
Sandpiper Bay
9.0 out of 10, Wonderful, (2 reviews)
"Host was very responsive and followed up on any issues that arose. "
United States
Joseph M.
The price is AED 720
AED 1,831 total
includes taxes & fees
2 Oct - 3 Oct
golf view villa near beach
3 bedrooms, iron/ironing board, internet, bed sheets

20. Relaxing 3BR Getaway w/Fire Pit & Close to Beaches

Relaxing 3BR Getaway w/Fire Pit & Close to Beaches
Lyngate
9.4 out of 10, Exceptional, (3 reviews)
"We had a wonderful stay! The home was very clean, comfortable, and exactly as described. The location was perfect. The host was responsive and made everything easy from check-in to check-out. The property felt family-friendly and welcoming, and we would definitely stay here again."
United States
JENNY U.
The price is AED 444
AED 1,188 total
includes taxes & fees
4 Oct - 5 Oct
Relaxing 3BR Getaway w/Fire Pit & Close to Beaches
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Port Saint Lucie Hotel Reviews

Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG

8/10 Good
"Solid stay. The staff was the best part! Very kind and hard working!"
Aaron 2-night trip
Posted 3 hours ago
Holiday Inn Express & Suites Port St. Lucie West by IHG