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Search Vacation Homes in Port Saint Lucie

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Check prices for these dates

In two weeks
26 Dec - 28 Dec
In two months
6 Feb - 8 Feb
In three months
6 Mar - 8 Mar
In four months
3 Apr - 5 Apr

Our top choices for Port Saint Lucie vacation homes

Outdoor pool, pool umbrellas, sun loungers
Sheraton PGA Vacation Resort, Port St. Lucie

Sheraton PGA Vacation Resort, Port St. Lucie

3.5 star property
Port Saint Lucie
9.0 out of 10, Wonderful, (645)
"Was very happy with our stay"
United States
matthew
The price is AED 411
AED 461 total
includes taxes & fees
16 Dec - 17 Dec
Sheraton PGA Vacation Resort, Port St. Lucie
Smart TV
Mini-Apartment

Mini-Apartment

Oak Hammock
8.6 out of 10, Excellent, (4)
"The place was great for me. Quite private and clean. It is close to 95 interstate and close to clover park. I was enjoying spring training and the beach. Host was excellent!"
United States
Robert L.
The price is AED 248
AED 516 total
includes taxes & fees
19 Dec - 20 Dec
Mini-Apartment
Indoor pool, outdoor pool
Cozy Oasis

Cozy Oasis

Port St. Lucie
9.0 out of 10, Wonderful, (59)
"Good host. Nice house. "
United States
Paul T.
The price is AED 327
AED 995 total
includes taxes & fees
10 Dec - 11 Dec
Cozy Oasis
Fridge, microwave, oven, stovetop
CHEERFUL 3 BEDROOM HOME

CHEERFUL 3 BEDROOM HOME

Port St. Lucie
9.0 out of 10, Wonderful, (12)
"Nice home, convenient location, fair price. Communication was very good and very much appreciated."
United States
Dave R.
The price is AED 367
AED 1,157 total
includes taxes & fees
12 Dec - 13 Dec
CHEERFUL 3 BEDROOM HOME
Fridge, microwave, oven, stovetop
BR Tropical Oasis in Port St Lucie

BR Tropical Oasis in Port St Lucie

2.0 star property
Port Saint Lucie
10.0 out of 10, Exceptional, (2)
"We are a construction company that had workers in from out of town and the place was great "
United States
Sabrina B.
The price is AED 451
AED 1,936 total
includes taxes & fees
14 Dec - 15 Dec
BR Tropical Oasis in Port St Lucie
Fridge, microwave, oven, stovetop
Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie

Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie

Sandpiper Bay
10.0 out of 10, Exceptional, (17)
"We threw our daughter's 3 year old birthday party here and the home was perfect for a festive weekend close to her grandparents. The home was exceptionally clean, the pool was awesome, highly recommended!"
United States
Eduardo S.
The price is AED 375
AED 1,154 total
includes taxes & fees
10 Dec - 11 Dec
Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie
Fridge, microwave, oven, stovetop
Treasure Coast-Blue House Relax

Treasure Coast-Blue House Relax

Northport Village
7.6 out of 10, Good, (7)
"Very clean and accommodating. "
United States
Gregory S.
The price is AED 441
AED 1,203 total
includes taxes & fees
10 Dec - 11 Dec
Treasure Coast-Blue House Relax
Fridge, microwave, oven, stovetop
3-bedroom house, 3 bathroom beautiful peaceful home in Port St. Lucie.

3-bedroom house, 3 bathroom beautiful peaceful home in Port St. Lucie.

Sandhill Crossing
9.6 out of 10, Exceptional, (8)
"Great location for us with golf and town nearby. Hostess was responsive and easy to work with. We'd stay again, nice house, clean and well equipped."
United States
Kelly N.
The price is AED 371
AED 1,106 total
includes taxes & fees
9 Jan - 10 January 2026
3-bedroom house, 3 bathroom beautiful peaceful home in Port St. Lucie.
Exterior
La Dolce Vita Studio

La Dolce Vita Studio

Port St. Lucie
9.4 out of 10, Exceptional, (10)
"Great location.Room is excellent with all basic needs.Will book again."
United States
james h.
The price is AED 367
AED 999 total
includes taxes & fees
1 Jan - 2 January 2026
La Dolce Vita Studio
Fridge, stovetop, coffee/tea maker, toaster
Charming 2-bedroom guesthouse with AC, WiFi in popular Port St. Lucie “private”

Charming 2-bedroom guesthouse with AC, WiFi in popular Port St. Lucie “private”

Port St. Lucie
7.4 out of 10, Good, (6)
"Private quaint"
United States
Jack H.
The price is AED 349
AED 629 total
includes taxes & fees
10 Dec - 11 Dec
Charming 2-bedroom guesthouse with AC, WiFi in popular Port St. Lucie “private”
Indoor spa tub
Poolside King Private Room in PSL

Poolside King Private Room in PSL

Port St. Lucie
10.0 out of 10, Exceptional, (2)
"David's home is very clean, with up-to-date interior decorating that is really attractive and calming. The screened in pool is lovely to use and relaxing just to watch from the dining area. The electronic keyless entry is the best I've ever experienced! Same for the washer and dryer. And David is such a wonderful person and REALLY cares that you are comfortable. He responded very quickly the couple of times I texted. And he met me at check in which I really appreciated."
United States
mary t.
The price is AED 419
AED 645 total
includes taxes & fees
10 Dec - 11 Dec
Poolside King Private Room in PSL
1 bedroom, iron/ironing board, free WiFi, bed sheets
Treasure Coast 1/1 Apartment - Beach, Golf & Relax

Treasure Coast 1/1 Apartment - Beach, Golf & Relax

Woodland Trails
9.6 out of 10, Exceptional, (9)
"Brand new property, convenient location."
United States
Jason M.
The price is AED 437
AED 748 total
includes taxes & fees
1 Jan - 2 January 2026
Treasure Coast 1/1 Apartment - Beach, Golf & Relax
Fridge, microwave, oven, stovetop
Beautiful and spacious 4BR house in Port St. Lucie, FL

Beautiful and spacious 4BR house in Port St. Lucie, FL

Port St. Lucie
8.4 out of 10, Very Good, (6)
"Very nice house great staying "
United States
Mario T.
The price is AED 569
AED 1,173 total
includes taxes & fees
14 Dec - 15 Dec
Beautiful and spacious 4BR house in Port St. Lucie, FL
Smart TV, computer monitors
Peaceful Cozy Modern 3 Bed Home

Peaceful Cozy Modern 3 Bed Home

Sandhill Crossing
10.0 out of 10, Exceptional, (7)
"We loved our stay here! The home was beautiful and clean and even nicer than the photos. Communication was easy and answered very quickly. I would definitely recommend this place. "
United States
Carmen
The price is AED 496
AED 1,239 total
includes taxes & fees
10 Dec - 11 Dec
Peaceful Cozy Modern 3 Bed Home
Interior
Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly

Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly

Lyngate
8.8 out of 10, Excellent, (5)
"We had an excellent stay as the house was very clean and the check in process was seamless. We appreciated all of Key's assistance."
United States
jmozden M.
The price is AED 474
AED 604 total
includes taxes & fees
10 Dec - 11 Dec
Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly
Outdoor pool, a heated pool
Beach like you've never seen! Heated pool/spa!

Beach like you've never seen! Heated pool/spa!

Port St. Lucie
10.0 out of 10, Exceptional, (31)
"The house was amazing. Despite not being close to the beach it felt beachy, which we really liked. We had everything we needed. "
United States
Betsy G.
The price is AED 661
AED 1,902 total
includes taxes & fees
16 Dec - 17 Dec
Beach like you've never seen! Heated pool/spa!
Interior
River Park Marine-House Vacation, 3B, 2B.

River Park Marine-House Vacation, 3B, 2B.

River Park
8.0 out of 10, Very Good, (1)
The price is AED 529
AED 1,312 total
includes taxes & fees
10 Dec - 11 Dec
River Park Marine-House Vacation, 3B, 2B.
Pool
The Poolside Escape (Near Beaches)

The Poolside Escape (Near Beaches)

2.0 star property
Floresta Gardens
The Poolside Escape (Near Beaches)
Dining
Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie

Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie

Lyngate
9.0 out of 10, Wonderful, (4)
"The house was comfortable. "
United States
C M.
The price is AED 547
AED 1,310 total
includes taxes & fees
1 Jan - 2 January 2026
Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie
Fridge, microwave, oven, stovetop
Lush | Tropical | Modern Home w/ Heated Pool & Spa

Lush | Tropical | Modern Home w/ Heated Pool & Spa

Sandhill Crossing
10.0 out of 10, Exceptional, (18)
"Great place to stay, private and relaxing. Location is close to just about everything. Will stay again :)"
United States
Scott T.
The price is AED 630
AED 2,072 total
includes taxes & fees
11 Dec - 12 Dec
Lush | Tropical | Modern Home w/ Heated Pool & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Port Saint Lucie Hotel Reviews

Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie

10/10 Excellent
"Great stay! Very friendly staff "
Giovanni 2-night trip
Posted 10 hours ago
Residence Inn by Marriott Port St. Lucie