A wooden pier extending into calm water with a sunset in the background.

Search Vacation Homes in Port Saint Lucie

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
30 Oct - 1 Nov
In two months
11 Dec - 13 Dec
In three months
8 Jan - 10 Jan
In four months
5 Feb - 7 Feb

Our top choices for Port Saint Lucie vacation homes

A hot tub with a built-in massage function, surrounded by string lights.

1. Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!

Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
Port St. Lucie
9.8 out of 10, Exceptional, (8 reviews)
"Great hospitality and I had not even a single issue. Everything was smooth and my stay was very comfortable. I’d definitely choose to stay there again in the future."
United States
Jeremiah L.
The price is AED 441
AED 670 total
includes taxes & fees
1 Nov - 2 Nov
Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
A spacious living area with a dining table, sofa, and a kitchen in the background.

2. Cozy Oasis

Cozy Oasis
Port St. Lucie
9.0 out of 10, Wonderful, (91 reviews)
"The house was great"
United States
Carlos
The price is AED 430
AED 1,120 total
includes taxes & fees
26 Oct - 27 Oct
Cozy Oasis
A dining area with a wooden table and chairs, a bench, and a wall-mounted TV.

3. Charming 2-bedroom guest house with Pool in Port St. Lucie

Charming 2-bedroom guest house with Pool in Port St. Lucie
Port St. Lucie
The price is AED 327
AED 666 total
includes taxes & fees
19 Oct - 20 Oct
Charming 2-bedroom guest house with Pool in Port St. Lucie
A bedroom with a bed, bedside table, dresser, and a ceiling fan.

4. Waterfront Canal Retreat w/ Private Entrance

Waterfront Canal Retreat w/ Private Entrance
Oak Hammock
The price is AED 349
AED 526 total
includes taxes & fees
19 Oct - 20 Oct
Waterfront Canal Retreat w/ Private Entrance
A covered outdoor area with a pool, seating, and a kitchen area.

5. Port St. Lucie Poolside Oasis

Port St. Lucie Poolside Oasis
2.0 star property
Port Saint Lucie
The price is AED 592
AED 1,782 total
includes taxes & fees
21 Oct - 22 Oct
Port St. Lucie Poolside Oasis
A residential area with houses, a swimming pool, and a red car parked in the driveway.

6. Private Pool Home Near Beach & Golf in FL

Private Pool Home Near Beach & Golf in FL
Palm Trails
8.0 out of 10, Very good, (1 review)
"Communication was clear and accurate. Pool and house were very nice. The kitchen wasn’t stocked well if you wanted to cook at the house. Very few pots, pans, etc."
United States
Tim A.
The price is AED 290
AED 1,325 total
includes taxes & fees
19 Oct - 20 Oct
Private Pool Home Near Beach & Golf in FL
Private kitchen

7. Marvelous 4-bedroom house with AC in Port St. Lucie

Marvelous 4-bedroom house with AC in Port St. Lucie
Northport Village
The price is AED 826
AED 2,200 total
includes taxes & fees
21 Oct - 22 Oct
Marvelous 4-bedroom house with AC in Port St. Lucie
A bedroom with a bed, a ceiling fan, a window with blinds, a small stool, and a patterned rug.

8. Relaxing 3BR Getaway w/Fire Pit & Close to Beaches

Relaxing 3BR Getaway w/Fire Pit & Close to Beaches
Lyngate
9.6 out of 10, Exceptional, (4 reviews)
"Exactly what we needed and the host is very understanding and worked with my family to make sure we were happy. The location is very convenient and close to local attractions."
United States
AJ H.
The price is AED 430
AED 1,238 total
includes taxes & fees
21 Oct - 22 Oct
Relaxing 3BR Getaway w/Fire Pit & Close to Beaches
An aerial view of a coastal area with a long pier extending into the sea, a beach with a few people, and buildings along the shore.

9. Lush | Tropical | Modern Home w/ Heated Pool & Spa

Lush | Tropical | Modern Home w/ Heated Pool & Spa
Sandhill Crossing
10.0 out of 10, Exceptional, (29 reviews)
"Loved the house and the pool area!"
United States
Brandy
The price is AED 476
AED 1,788 total
includes taxes & fees
19 Oct - 20 Oct
Lush | Tropical | Modern Home w/ Heated Pool & Spa
A bookshelf with various books, a framed picture of the ocean, a desk lamp, and a woven basket.

10. Bohemian Bungalow

Bohemian Bungalow
Port St. Lucie
10.0 out of 10, Exceptional, (8 reviews)
"This was the perfect place to stay. The house had everything we could need and Lisa was wonderful!"
United States
Sydney M.
The price is AED 476
AED 1,272 total
includes taxes & fees
28 Oct - 29 Oct
Bohemian Bungalow
A room with a large window overlooking a wooden deck with a thatched roof, a pool, and outdoor seating.

11. Waterfront Tiki Oasis - Dock & Ocean Access

Waterfront Tiki Oasis - Dock & Ocean Access
River Park
10.0 out of 10, Exceptional, (1 review)
"Great place to stay. Clean and a perfect location. We will definitely stay here again. "
United States
Shaun B.
The price is AED 496
AED 1,547 total
includes taxes & fees
25 Oct - 26 Oct
Waterfront Tiki Oasis - Dock & Ocean Access
A beach with clear water, a sandy shore, and a clear sky.

12. Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!

Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!
Port St. Lucie
10.0 out of 10, Exceptional, (6 reviews)
"Muy acogedor , excelente para pasar en familia , con todas las condiciones 👌"
United States
Jeiny
The price is AED 771
AED 1,903 total
includes taxes & fees
16 Nov - 17 Nov
Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!
A kitchen with wooden cabinets, stainless steel appliances, and a tiled backsplash.

13. Casa del Sol PSL — Newly Remodeled Pool Retreat

Casa del Sol PSL — Newly Remodeled Pool Retreat
Lyngate
Casa del Sol PSL — Newly Remodeled Pool Retreat
A bedroom with a bed, a dresser, a nightstand, a lamp, a ceiling fan, a window with blinds, and a round mirror on the wall.

14. Lovely 4-bedroom house in Port St Lucie

Lovely 4-bedroom house in Port St Lucie
Gatlin Pines
The price is AED 608
AED 1,496 total
includes taxes & fees
19 Oct - 20 Oct
Lovely 4-bedroom house in Port St Lucie
A modern kitchen with dark cabinetry, stainless steel appliances, and a granite countertop.

15. Modern 4 Bdr Home near Tradition Town Center

Modern 4 Bdr Home near Tradition Town Center
Oak Hammock
9.6 out of 10, Exceptional, (5 reviews)
"This is a modern, well equipped home in a nice neighborhood. Its close to everything. Beach, golf, restaurants and pubs. "
United States
Scott B.
Modern 4 Bdr Home near Tradition Town Center
A residential area with houses, lawns, and a clear sky.

16. The Glentry - Your Home Away From Home

The Glentry - Your Home Away From Home
Northport Village
The price is AED 579
AED 1,573 total
includes taxes & fees
19 Oct - 20 Oct
The Glentry - Your Home Away From Home
A coastal road with palm trees, a sign for South Causeway State Park, and a sunset in the background.

17. Coastal Haven Retreat

Coastal Haven Retreat
Becker Ridge
The price is AED 600
AED 1,626 total
includes taxes & fees
19 Oct - 20 Oct
Coastal Haven Retreat
A residential property with a garage, a driveway, and a well-maintained lawn.

18. Modern 4-bedroom House Very Spacious with Pool Table Game

Modern 4-bedroom House Very Spacious with Pool Table Game
Floresta Gardens
10.0 out of 10, Exceptional, (1 review)
"Super Clean, Very Responsive,"
United States
edixander t.
The price is AED 735
AED 2,215 total
includes taxes & fees
16 Nov - 17 Nov
Modern 4-bedroom House Very Spacious with Pool Table Game
A bedroom with a bed, a television on a stand, a closet with hanging clothes, and a door leading to another room.

19. Port St. Lucie Poolside Oasis

Port St. Lucie Poolside Oasis
Port St. Lucie
The price is AED 705
AED 1,908 total
includes taxes & fees
19 Oct - 20 Oct
Port St. Lucie Poolside Oasis
Private kitchen

20. Villa Blue - Private Heated Pool - Sleeps 8

Villa Blue - Private Heated Pool - Sleeps 8
Sandpiper Bay
10.0 out of 10, Exceptional, (23 reviews)
"Amazing place! So many fun things to do and was so beautiful on the inside!"
United States
Victoria K.
The price is AED 735
AED 1,649 total
includes taxes & fees
26 Oct - 27 Oct
Villa Blue - Private Heated Pool - Sleeps 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Port Saint Lucie Hotel Reviews

voco Sandpiper All-Inclusive Resort by IHG

voco Sandpiper All-Inclusive Resort by IHG

10/10 Excellent
"La habitación muy limpia,el personal atento,los bartender,en el restaurante,el frontdesk,Dakota y Claire,las instalaciones muy bonita,muchas actividades juegos,la verdad,sencillo pero acogedor"
Yamileidy 2-night trip
Posted 1 hour ago
voco Sandpiper All-Inclusive Resort by IHG