A wooden pier extending into calm water with a sunset in the background.

Search Vacation Homes in Port Saint Lucie

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Port Saint Lucie vacation homes

1. Charming 2-bedroom guest house with Pool in Port St. Lucie

Charming 2-bedroom guest house with Pool in Port St. Lucie
Port St. Lucie
2.0 out of 10, (1 review)
The price is AED 360
AED 715 total
includes taxes & fees
16 Nov - 17 Nov
Charming 2-bedroom guest house with Pool in Port St. Lucie

2. Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!

Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
Port St. Lucie
9.8 out of 10, Exceptional, (9 reviews)
"Friendly host, great room and amazing pool and hot tub. "
United States
Matthew B.
The price is AED 419
AED 673 total
includes taxes & fees
14 Nov - 15 Nov
Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!

3. Relaxing 3BR Getaway w/Fire Pit & Close to Beaches

Relaxing 3BR Getaway w/Fire Pit & Close to Beaches
Lyngate
9.8 out of 10, Exceptional, (9 reviews)
"We had a wonderful stay! The home was very clean, comfortable, and exactly as described. The location was perfect. The host was responsive and made everything easy from check-in to check-out. The property felt family-friendly and welcoming, and we would definitely stay here again."
United States
JENNY U.
The price is AED 389
AED 1,127 total
includes taxes & fees
15 Nov - 16 Nov
Relaxing 3BR Getaway w/Fire Pit & Close to Beaches

4. Waterfront Canal Retreat w/ Private Entrance

Waterfront Canal Retreat w/ Private Entrance
Oak Hammock
Waterfront Canal Retreat w/ Private Entrance

5. Private Pool Home Near Beach & Golf in FL

Private Pool Home Near Beach & Golf in FL
Palm Trails
8.0 out of 10, Very good, (1 review)
"Communication was clear and accurate. Pool and house were very nice. The kitchen wasn’t stocked well if you wanted to cook at the house. Very few pots, pans, etc."
United States
Tim A.
Private Pool Home Near Beach & Golf in FL

6. Cozy Oasis

Cozy Oasis
Port St. Lucie
9.0 out of 10, Wonderful, (93 reviews)
"The house was great"
United States
Carlos
The price is AED 588
AED 1,264 total
includes taxes & fees
10 Dec - 11 Dec
Cozy Oasis

7. La Dolce Vita Studio

La Dolce Vita Studio
Port St. Lucie
9.6 out of 10, Exceptional, (11 reviews)
"Great location.Room is excellent with all basic needs.Will book again."
United States
james h.
La Dolce Vita Studio

8. CHEERFUL 3 BEDROOM HOME

CHEERFUL 3 BEDROOM HOME
Port St. Lucie
8.4 out of 10, Very good, (16 reviews)
"The location was very convenient and they accept pets! "
United States
CATHERINE M.
CHEERFUL 3 BEDROOM HOME

9. Bohemian Bungalow

Bohemian Bungalow
Port St. Lucie
10.0 out of 10, Exceptional, (8 reviews)
"This was the perfect place to stay. The house had everything we could need and Lisa was wonderful!"
United States
Sydney M.
The price is AED 494
AED 1,262 total
includes taxes & fees
19 Nov - 20 Nov
Bohemian Bungalow

10. Waterfront Tiki Oasis - Dock & Ocean Access

Waterfront Tiki Oasis - Dock & Ocean Access
River Park
10.0 out of 10, Exceptional, (1 review)
"Great place to stay. Clean and a perfect location. We will definitely stay here again. "
United States
Shaun B.
Waterfront Tiki Oasis - Dock & Ocean Access

11. Modern 3BR Pool Home with Lanai: PSL Coastal Calm Retreat! Beach! Golf! Boating!

Modern 3BR Pool Home with Lanai: PSL Coastal Calm Retreat! Beach! Golf! Boating!
Port St. Lucie
10.0 out of 10, Exceptional, (6 reviews)
"This is a great property, close to everything . The view from the kitchen to the pool it’s so nice. Communication with the owner was great. Super clean house ."
United States
Karla N.
The price is AED 551
AED 1,550 total
includes taxes & fees
14 Nov - 15 Nov
Modern 3BR Pool Home with Lanai: PSL Coastal Calm Retreat! Beach! Golf! Boating!

12. Chic & Peaceful Retreat Close to It All

Chic & Peaceful Retreat Close to It All
Port St. Lucie
The price is AED 479
AED 1,084 total
includes taxes & fees
27 Nov - 28 Nov
Chic & Peaceful Retreat Close to It All

13. Modern 4-bedroom House Very Spacious with Pool Table Game

Modern 4-bedroom House Very Spacious with Pool Table Game
Floresta Gardens
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful stay! The property was spotless, beautiful, and very comfortable. The host was amazing, and everything exceeded our expectations. Highly recommended—we would love to return! "
United States
Maylin M.
The price is AED 826
AED 2,325 total
includes taxes & fees
1 Dec - 2 Dec
Modern 4-bedroom House Very Spacious with Pool Table Game

14. The Great Escape - 4 BR golf villa in paradise

The Great Escape - 4 BR golf villa in paradise
Port St. Lucie
9.8 out of 10, Exceptional, (27 reviews)
"A very bright clean, spotless home easy access to Golf Course. Everything was just great."
United States
Dino M.
The Great Escape - 4 BR golf villa in paradise

15. Beach like you've never seen! Heated pool/spa!

Beach like you've never seen! Heated pool/spa!
Port St. Lucie
10.0 out of 10, Exceptional, (42 reviews)
"Great house with everything you want for a vacation home. The hosts were very responsive when we reached out. We plan to stay there again next year."
United States
Kenneth C.
The price is AED 915
AED 2,174 total
includes taxes & fees
30 Nov - 1 Dec
Beach like you've never seen! Heated pool/spa!

16. Villa Blue - Private Heated Pool - Sleeps 8

Villa Blue - Private Heated Pool - Sleeps 8
Sandpiper Bay
10.0 out of 10, Exceptional, (24 reviews)
"Amazing place! So many fun things to do and was so beautiful on the inside!"
United States
Victoria K.
The price is AED 668
AED 1,501 total
includes taxes & fees
10 Dec - 11 Dec
Villa Blue - Private Heated Pool - Sleeps 8

17. Lovely 4-bedroom house in Port St Lucie

Lovely 4-bedroom house in Port St Lucie
Gatlin Pines
Lovely 4-bedroom house in Port St Lucie

18. 4BR, 2BA with Heated Pool, BBQ, Fire pit in Port St. Lucie

4BR, 2BA with Heated Pool, BBQ, Fire pit in Port St. Lucie
Lyngate
9.6 out of 10, Exceptional, (7 reviews)
"I really love this place very clean and my family love everything about it will staying there again"
United States
suanna c.
The price is AED 621
AED 1,587 total
includes taxes & fees
17 Nov - 18 Nov
4BR, 2BA with Heated Pool, BBQ, Fire pit in Port St. Lucie

19. Charming 9-bed house in lovely Port St. Lucie with AC

Charming 9-bed house in lovely Port St. Lucie with AC
Northport Village
The price is AED 727
AED 1,793 total
includes taxes & fees
15 Nov - 16 Nov
Charming 9-bed house in lovely Port St. Lucie with AC

20. golf view villa near beach

golf view villa near beach
Sandpiper Bay
9.0 out of 10, Wonderful, (2 reviews)
"Host was very responsive and followed up on any issues that arose. "
United States
Joseph M.
golf view villa near beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Port Saint Lucie Hotel Reviews