A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

Puxico Vacation Rentals

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Check prices for these dates

In two weeks
28 Aug - 30 Aug
In two months
9 Oct - 11 Oct
In three months
6 Nov - 8 Nov
In four months
4 Dec - 6 Dec

Our top choices for Puxico vacation rentals

Property grounds

1. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
10.0 out of 10, Exceptional, (1 review)
"Very cozy"
United States
Shea E.
The price is AED 512
AED 991 total
includes taxes & fees
17 Aug - 18 Aug
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Front of property

2. Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
9.0 out of 10, Wonderful, (4 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is AED 281
AED 296 total
includes taxes & fees
24 Aug - 25 Aug
Lake Wappapello
Property grounds

3. Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided

Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided
Greenville
10.0 out of 10, Exceptional, (8 reviews)
"This place is amazing! We've stayed at a lot of different VRBOs and this is by far one of the best! Thanks for having us and we'll definitely be back"
United States
Joshua H.
The price is AED 694
AED 1,125 total
includes taxes & fees
24 Aug - 25 Aug
Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided
Exterior

4. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
8.0 out of 10, Very Good, (36 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
The price is AED 393
AED 796 total
includes taxes & fees
17 Aug - 18 Aug
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Coffee/tea maker, fridge, microwave, oven

5. Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
The price is AED 679
AED 1,369 total
includes taxes & fees
17 Aug - 18 Aug
Hunting / Fishing Cabin at Lake Wappapello
Exterior detail

6. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
8.8 out of 10, Excellent, (15 reviews)
"House was great. Will definitely be back."
United States
Anonymous traveler
The price is AED 422
AED 1,051 total
includes taxes & fees
19 Aug - 20 Aug
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Interior

7. Cozy hobby farm cabin under the stars!

Cozy hobby farm cabin under the stars!
Greenville
10.0 out of 10, Exceptional, (8 reviews)
"Easy check in, very quiet, very calming and relaxing. Overall great stay and great property manager. "
United States
Wyatt S.
The price is AED 272
AED 439 total
includes taxes & fees
9 Sep - 10 Sep
Cozy hobby farm cabin under the stars!
Coffee/tea maker, fridge, microwave, oven

8. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
The price is AED 477
AED 591 total
includes taxes & fees
17 Aug - 18 Aug
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Puxico Hotel Reviews

Econo Lodge Dexter

Econo Lodge Dexter

10/10 Excellent
"Pretty much just slept, but it all was peaceful!"
chuck 1-night trip
Posted 1 hour ago
Econo Lodge Dexter

Frequently asked questions

Are there vacation rentals in Puxico?

Yes, we offer vacation rentals close to popular sights in Puxico, or you can go with a more remote option if you're looking for a relaxing stay.

What's the top vacation rental that Puxico has to offer?

Private lake, beach & hot tub, romantic getaway or family vaca: This vacation home rental near Puxico is equipped with a hot tub, air-conditioning, and laundry facilities to help you feel comfortable during your stay.

What’s there to see and do in Puxico?

While exploring the area, visit family-friendly sights like Dexter Welcome Center Depot and Museum, or get outside and enjoy nature at Mark Twain National Forest. In the larger area, you’ll find Mingo Wilderness and Lake Wappapello.

What’s a vacation rental in Puxico like?

A vacation rental is a private property where you can stay for a couple of days or more in Puxico. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family getaway.