Puxico Vacations

Book a Hotel + Flight together to unlock savings

Photo by Mike McClain

  • Plan, book, travel with confidence

  • Better together

    Save up to AEDĀ 5,000 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Find the Best Puxico Vacation Packages

Puxico Hotel Deals

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
The price is AEDĀ 257 per night from Jul 30 to Jul 31
AEDĀ 257
AEDĀ 288 total
30 Jul - 31 Jul
includes taxes & fees
8/10 Very Good! (1,000 reviews)
"Really clean, in a decent area, great vaue"

Reviewed on 28 July 2026

Motel 6 Poplar Bluff, MO
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3 out of 5
3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
The price is AEDĀ 387 per night from Aug 6 to Aug 7
AEDĀ 387
AEDĀ 437 total
6 Aug - 7 Aug
includes taxes & fees
9.4/10 Exceptional! (943 reviews)
"Nice clean area and motel."

Reviewed on 29 July 2026

Fairfield Inn & Suites by Marriott Poplar Bluff
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
The price is AEDĀ 359 per night from Aug 13 to Aug 14
AEDĀ 359
AEDĀ 402 total
13 Aug - 14 Aug
includes taxes & fees
9.4/10 Exceptional! (909 reviews)
"The property was very well maintained. Staff was very friendly. Very clean. Only complaint was cleaning ladies threw away a razor my daughter had in shower. It was not a disposable one. They could have just left it where it was."

Reviewed on 28 July 2026

Hampton Inn Poplar Bluff
See all 56 properties in Puxico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Puxico vacation package cost?
You can pick up a vacation package to this destination on Expedia. But how much your vacation to Puxico costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Puxico?
January, February and November are great times to look for cheap Puxico vacation packages. Choosing to travel in less busy months means you'll typically find reduced prices on flights and hotels.
How to find the best Puxico package deals?
Use Expedia's filter tool to help you find some of the best Puxico package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or browse for Puxico package deals in the off-peak season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Puxico vacation as a package?
You can enjoy significant savings on your next Puxico escape by booking a personalized vacation package. Check the "Package" heading, then select your destination and travel dates to see some great airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Puxico?
If you've got your Puxico vacation dates confirmed, book as soon as you can to score some outstanding deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous getaways? Our last-minute deals are perfect for setting off on a whim.
How to plan a trip to Puxico?

  1. Pick the best time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to travel to Puxico.
  2. Set your budget: Consider expenses such as flights, food and transportation when calculating how much to save for your trip to Puxico. Then, pick a hotel that suits your budget, whether that's an affordable stay or a deluxe getaway.
  3. Decide how many days away: Start by making a list of all the attractions and activities you'd like to experience in Puxico. Then, estimate how long you'll need for each, including any travel time.
  4. Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left now is to choose a Puxico vacation package that brings all your bookings together.