Search Vacation Homes in Rochester

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Rochester vacation homes

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Rochester
10.0 out of 10, Exceptional, (2 reviews)
"This was a fantastic experience, far better than anticipated! Only a couple of comments: this high tech house was a little over the head of my crew and a guidebook to show us how to use all those remotes would have been most welcome. And one of my folks was looking for a can opener… We had a lovely time and the next convention we have in Rochester I will book here again without hesitation! "
United States
Patricia B.
The price is AED 1,304
AED 1,717 total
includes taxes & fees
26 Mar - 27 Mar
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (141 reviews)
"Great place to stay."
United States
Matthew S.
The price is AED 217
AED 440 total
includes taxes & fees
27 Mar - 28 Mar
Magical Nest Hideaway

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Slatterly Park
10.0 out of 10, Exceptional, (22 reviews)
"This is a great property! Highly recommend!"
United States
Anne G.
The price is AED 663
AED 869 total
includes taxes & fees
26 Mar - 27 Mar
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Luxurious Sweet Escape stunning custom Home!

Luxurious Sweet Escape stunning custom Home!
Rochester
Luxurious Sweet Escape stunning custom Home!

2 Blks St Marys Main Fl Beds Bath CoveredByFaith

2 Blks St Marys Main Fl Beds Bath CoveredByFaith
Kutzky Park
10.0 out of 10, Exceptional, (101 reviews)
"Easy check in and host was very helpful "
United States
Joshua M.
2 Blks St Marys Main Fl Beds Bath CoveredByFaith

Custom Luxury Rambler in Highland Hills, Rochester

Custom Luxury Rambler in Highland Hills, Rochester
Rochester
Custom Luxury Rambler in Highland Hills, Rochester

Close to Mayo & Shops, 1 step entry CoveredByFaith

Close to Mayo & Shops, 1 step entry CoveredByFaith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"The host was so incredibly responsive whenever we had questions, the house was incredibly clean and welcoming, and we enjoyed our stay there."
United States
Anonymous traveler
Close to Mayo & Shops, 1 step entry CoveredByFaith

2 step entry 1 mile to Mayo CoveredByFaith Inspire

2 step entry 1 mile to Mayo CoveredByFaith Inspire
Parkway
2 step entry 1 mile to Mayo CoveredByFaith Inspire

Charming Family 1-level and pet-friendly Home

Charming Family 1-level and pet-friendly Home
Austin
8.8 out of 10, Excellent, (23 reviews)
"The place was perfect. Good location. The host was available when I had a question. Will stay here again. "
United States
Molly M.
The price is AED 298
AED 519 total
includes taxes & fees
28 Mar - 29 Mar
Charming Family 1-level and pet-friendly Home

2.5 miles to Mayo, 4 step entry Covered By Faith

2.5 miles to Mayo, 4 step entry Covered By Faith
Rochester
2.5 miles to Mayo, 4 step entry Covered By Faith

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Slatterly Park
10.0 out of 10, Exceptional, (21 reviews)
"I love staying in their properties. I always know I am going to be comfortable and have a great stay. "
United States
Carissa W.
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

1742 Uptown // Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly

1742 Uptown // Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly
Rochester
10.0 out of 10, Exceptional, (23 reviews)
"The location of the home was perfect and so close to our appointments at the Mayo Clinic. Becca was a great host and provided us with everything we needed. We really enjoyed the home and all of its amenities. It was very comfortable and there was so much space if we would have needed it. We highly recommend staying at this wonderful home!"
United States
Lynn P.
1742 Uptown // Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly

1st Luxury Residential Elevator rooftop deck

1st Luxury Residential Elevator rooftop deck
Rochester
1st Luxury Residential Elevator rooftop deck

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Washington
9.8 out of 10, Exceptional, (24 reviews)
"Beautiful and CLEAN, convenient location. Will definitely stay again!"
United States
Melissa W.
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

4 blks St Marys Main fl beds/bath CoveredByFaith

4 blks St Marys Main fl beds/bath CoveredByFaith
Kutzky Park
9.8 out of 10, Exceptional, (59 reviews)
"We enjoyed our stay."
United States
Joseph V.
4 blks St Marys Main fl beds/bath CoveredByFaith

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
Rochester
10.0 out of 10, Exceptional, (6 reviews)
"This property had everything we needed. Super cute and simple decor, comfortable beds and clean. We would stay here again!! "
United States
Anonymous traveler
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
Rochester
9.8 out of 10, Exceptional, (7 reviews)
"Nice place to stay, close to all the activities we wanted to do."
United States
Kimberly K.
Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith

3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
Folwell
9.6 out of 10, Exceptional, (25 reviews)
"Jessica was more than welcoming and made sure everything was set and perfect for our last minute stay in Rochester. House was in a great location and even the snow was cleared from the driveway so we had no issues getting in. The house was spotless and had everything we needed. Thanks again!"
United States
Jen T.
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith

7 blks Mayo Gonda 8 blks St Marys 3 Bed Main Floor

7 blks Mayo Gonda 8 blks St Marys 3 Bed Main Floor
Kutzky Park
9.4 out of 10, Exceptional, (16 reviews)
"It is an older house but kept in good condition. "
United States
Al G.
The price is AED 422
AED 1,068 total
includes taxes & fees
29 Mar - 30 Mar
7 blks Mayo Gonda 8 blks St Marys 3 Bed Main Floor

1 mile to Mayo 2 step entry Brave Covered By Faith

1 mile to Mayo 2 step entry Brave Covered By Faith
Parkway
9.8 out of 10, Exceptional, (10 reviews)
"This was a PERFECT place to stay if you're going to the Mayo!Jessica is very easy to work with and incredibly responsive!"
United States
Kristin T.
1 mile to Mayo 2 step entry Brave Covered By Faith
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Rochester Hotel Reviews

Explore a world of travel with Expedia