Saint Charles Vacations

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Find the Best Saint Charles Vacation Packages

Saint Charles Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
The price is AED 494 per night from Feb 25 to Feb 26
AED 494
AED 553 total
25 Feb - 26 Feb
includes taxes & fees
9.4/10 Exceptional! (1,081 reviews)
The room was very clean

Reviewed on 5 February 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2 out of 5
7625 Office Plaza Dr N West Des Moines IA
Fully refundableReserve now, pay when you stay
The price is AED 215 per night from Mar 11 to Mar 12
AED 215
AED 241 total
11 Mar - 12 Mar
includes taxes & fees
8.2/10 Very Good! (973 reviews)
A very good hotel for the price. Friendly staff. Clean room, but quite old building and interior. The shower in the room was old and squeaky.

Reviewed on 6 February 2026

Sonesta Simply Suites Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
The price is AED 328 per night from Feb 15 to Feb 16
AED 328
AED 368 total
15 Feb - 16 Feb
includes taxes & fees
9.2/10 Wonderful! (1,010 reviews)
Clean, spacious, great amenities, and the sheets were super soft.

Reviewed on 5 February 2026

Home2 Suites by Hilton Des Moines at Drake University
See all 622 properties in Saint Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How do I find cheap flights to Saint Charles that have flexible change policies?
Search for cheap fares to Saint Charles, then select "No change fee" under the "Flexible change policies" filter. It really is that easy. We know that plans can change and flexibility matters, so you can book with confidence with Expedia.
Which airlines fly to Saint Charles?
Grab a seat with one of these airlines and the exciting region of Saint Charles will be yours to discover:

  • American Airlines - 407 flights to or near Saint Charles each month, including 407 flights to Des Moines Intl. Airport (DSM) per month.
  • United Airlines - 294 flights to or near Saint Charles each month, including 294 flights to Des Moines Intl. Airport (DSM) per month.
  • Delta Air Lines - 229 flights to or near Saint Charles each month, including 229 flights to Des Moines Intl. Airport (DSM) per month.

How can I find cheap tickets to Saint Charles?
One of the best ways to snare cheap tickets to Saint Charles is to be flexible with your travel dates. Search for your flights, then click "flexible dates" above the results. It will reveal the cheapest prices for nearby days. The best price for a flight to Saint Charles in the last seven days was . Booking in advance will usually help you get an even bigger bargain.
How much is a flight to Saint Charles?
In the last seven days, round-trip tickets to Saint Charles sold for as little as and reached a maximum cost of . For one-way trips taking off from (), the lowest price during this same period was just .
What are the most popular airports to fly into in Saint Charles?
Start arranging your Saint Charles adventure by reserving one of the 1,200 monthly flights to Des Moines Intl. Airport (DSM). This is the region's main entryway.
When is the cheapest time to fly to Saint Charles?
Try to jet off early in the week to get a bargain fare to Saint Charles. Tuesday is commonly the cheapest day to take off, with Monday a close second. Saturday often has the costliest fares. This is because many travelers choose to kick off their break on a weekend.
How much is a plane ticket to Saint Charles?
Seats ranged anywhere from to over the last seven days. When you're ready to book, we're here to help you lock in an awesome deal to Saint Charles.
What months are the cheapest to book a flight to Saint Charles?
To secure a fabulous deal to Saint Charles, try to book during February when the prices are at their lowest. When's the most costly? In the USA, it's December.
How long is a flight to Saint Charles?
It depends on where you travel from. These in-demand domestic routes and their average flight times will give you a clearer picture of how long it'll take to reach Saint Charles:

  • Denver, CO (DEN-Denver Intl.) to Des Moines Intl. Airport (DSM) - 1 hour and 42 minutes
  • Chicago, IL (ORD-O'Hare Intl.) to Des Moines Intl. Airport (DSM) - 1 hour and 25 minutes
  • Dallas, TX (DFW-Dallas-Fort Worth Intl.) to Des Moines Intl. Airport (DSM) - 1 hour and 54 minutes