A person in a red jacket and black boots standing on a sandy beach, a dog walking beside them, and another person paddling a kayak in calm water.

Search Vacation Homes in Salem

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for Salem vacation homes

An aerial view of a marina with multiple docks, a swimming pool, and a building with a dock extending into the water.

1. Lake Keowee: Resort Pools & Spa, Family Game Room, Golf, Clemson

Lake Keowee: Resort Pools & Spa, Family Game Room, Golf, Clemson
Salem
9.8 out of 10, Exceptional, (60 reviews)
"The place was clean and as described. Host was very responsive and pleasant. Thank you!"
United States
Heather D.
The price is AED 701
AED 2,383 total
includes taxes & fees
15 Oct - 16 Oct
Lake Keowee: Resort Pools & Spa, Family Game Room, Golf, Clemson
A two-story house with a covered porch and a small gazebo.

2. Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park

Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park
Salem
10.0 out of 10, Exceptional, (32 reviews)
"Beautiful home. Loved our stay and hope to be back!"
United States
Erin L.
The price is AED 1,286
AED 2,291 total
includes taxes & fees
19 Oct - 20 Oct
Lake Jocassee retreat on two acres!! New hot tub, Devil’s Fork State Park
A hallway with wooden flooring, white walls, and a white door on the right.

3. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
The price is AED 485
AED 1,585 total
includes taxes & fees
19 Oct - 20 Oct
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
A wooden porch with a rocking chair and a table, a stone wall, and a welcome sign.

4. “The Happy Place” River front cabin with dock

“The Happy Place” River front cabin with dock
Mountain Rest
9.4 out of 10, Exceptional, (35 reviews)
"Cabin was wonderful"
United States
William W.
The price is AED 632
AED 1,455 total
includes taxes & fees
14 Oct - 15 Oct
“The Happy Place” River front cabin with dock
A bedroom with a bed, a nightstand, a lamp, a window with blinds, a ceiling fan, and a painting on the wall.

5. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
The price is AED 397
AED 1,046 total
includes taxes & fees
12 Oct - 13 Oct
Peaceful 3-bedroom home 4 miles from Clemson.
A lakeside cabin with a dock, a floating platform, and a house in the background.

6. Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option

Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
West Union
9.6 out of 10, Exceptional, (17 reviews)
"Great home. Neat and Clean. We had family 3-70 and there was something for everyone to do and enjoy during our stay. Host was very prompt with communication and answering my questions. Would stay here again."
United States
April O.
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
A modern kitchen with a central island, wooden cabinets, and a built-in refrigerator.

7. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (12 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is AED 777
AED 1,347 total
includes taxes & fees
11 Oct - 12 Oct
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
A dining area with a wooden table, chairs, and a hanging light fixture.

8. Iroquois Crossroads - 10 min from Clemson & lakes

Iroquois Crossroads - 10 min from Clemson & lakes
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Couldn't have been an easier process. Place was immaculate. Would recommend."
United States
Steve M.
Iroquois Crossroads - 10 min from Clemson & lakes
A covered patio with a brick wall, a large tree, a wicker sofa, a metal chair, and a tiled floor.

9. Welcome To Downtown Pickens close to Clemson and Lake Keowee

Welcome To Downtown Pickens close to Clemson and Lake Keowee
Pickens
10.0 out of 10, Exceptional, (41 reviews)
"Everything was as described"
United States
Sandy J.
The price is AED 397
AED 966 total
includes taxes & fees
21 Oct - 22 Oct
Welcome To Downtown Pickens close to Clemson and Lake Keowee
A bedroom with a bed, a dresser, a nightstand, a lamp, and a painting on the wall.

10. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
The price is AED 635
AED 1,350 total
includes taxes & fees
11 Oct - 12 Oct
Renovated 3BR near Lake Keowee & Clemson
A cozy living room with two armchairs, a dark wooden mantelpiece with decorative items, and a kitchen in the background.

11. Birch Cabin | Pet-Friendly Stay at Cashier's Lake

Birch Cabin | Pet-Friendly Stay at Cashier's Lake
Cashiers
9.4 out of 10, Exceptional, (10 reviews)
The price is AED 558
AED 1,359 total
includes taxes & fees
13 Oct - 14 Oct
Birch Cabin | Pet-Friendly Stay at Cashier's Lake
A spacious living area with a high ceiling, a stone fireplace, and large windows offering views of the outdoors.

12. Happy Trails: Jacuzzi, Lookout Tower, Views!

Happy Trails: Jacuzzi, Lookout Tower, Views!
Pickens
9.8 out of 10, Exceptional, (13 reviews)
"Great stay!"
United States
Anonymous traveler
The price is AED 851
AED 3,236 total
includes taxes & fees
22 Oct - 23 Oct
Happy Trails: Jacuzzi, Lookout Tower, Views!
A living room with a large tiger mural, a fireplace, a sofa, and a coffee table.

13. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (22 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is AED 591
AED 1,327 total
includes taxes & fees
27 Oct - 28 Oct
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
A deck with four Adirondack chairs and a small table, overlooking a mountainous landscape.

14. Spacious 5-BR House with Long Range Views of Mtns. & Lake Jocassee,Near Brevard!

Spacious 5-BR House with Long Range Views of Mtns. & Lake Jocassee,Near Brevard!
Brevard
10.0 out of 10, Exceptional, (6 reviews)
"We enjoyed our stay here very much. If you’re looking for a rustic cabin to unplug and enjoy top notch views, this is the place for you. It is a bit remote which was a positive for us but keep that in mind if you book. We grilled out in the evenings and enjoyed spending time with our family. "
United States
Monica
The price is AED 1,308
AED 2,606 total
includes taxes & fees
18 Oct - 19 Oct
Spacious 5-BR House with Long Range Views of Mtns. & Lake Jocassee,Near Brevard!
An outdoor seating area with red plastic chairs arranged around a central fire pit, surrounded by a forested area with blue string lights overhead.

15. Black Bear Hideaway

Black Bear Hideaway
Pickens
9.6 out of 10, Exceptional, (11 reviews)
"Great place. "
United States
Sarah J.
Black Bear Hideaway
A small, dark green, triangular-shaped cabin with a red roof, a white door, and two windows on each side.

16. Hilda’s Hideaway- a charming little A-frame

Hilda’s Hideaway- a charming little A-frame
Rosman
10.0 out of 10, Exceptional, (6 reviews)
"Beautiful cabin. Nice proximity to Brevard"
United States
Josh G.
The price is AED 441
AED 1,096 total
includes taxes & fees
9 Nov - 10 Nov
Hilda’s Hideaway- a charming little A-frame
A lodge with a gravel driveway, wooden steps, and a stone pathway leading to the entrance.

17. Dogwood Cabin | Lake-View Stay at Cashiers Lake

Dogwood Cabin | Lake-View Stay at Cashiers Lake
Cashiers
9.8 out of 10, Exceptional, (14 reviews)
"We had the best time, and will definitely be back!"
United States
Amanda J.
Dogwood Cabin | Lake-View Stay at Cashiers Lake
A cozy living room with a fireplace, a dining area with a table and chairs, and a kitchen in the background.

18. Clemson Memorabilia House Frank Howard III’s Home

Clemson Memorabilia House Frank Howard III’s Home
Clemson
8.4 out of 10, Very good, (20 reviews)
The price is AED 316
AED 970 total
includes taxes & fees
11 Oct - 12 Oct
Clemson Memorabilia House Frank Howard III’s Home
A covered outdoor seating area with wicker furniture and a fireplace.

19. Cozy-Family Friendly-Game Room-

Cozy-Family Friendly-Game Room-
Highlands
9.6 out of 10, Exceptional, (32 reviews)
"We had a great time. It is perfect for a quiet escape & it is close to enough to Main Street, if you desire to go. The covered deck & fireplace was our spot we never left."
United States
Derek
The price is AED 635
AED 2,112 total
includes taxes & fees
3 Nov - 4 Nov
Cozy-Family Friendly-Game Room-
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Salem Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"lovely hotel and wonderful staff"
MartinandHeather 1-night trip
Posted 9 hours ago
The Shepherd Hotel Downtown Clemson