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Discover 1,278 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Front of property
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (2444)
"This hotel was very clean. There are three restaurants in it. The food was excellent. I had to call the housekeeping staff several times to get a laundry bag. I had to call Reception to get the hand soap and shower gel replaced when both obviously needed a refill. "
The price is AED 437
AED 481 total
includes taxes & fees
29 May - 30 May
Hotel Riu Plaza Panama
Pool
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1001)
"Nice place to stay in Panama"
The price is AED 673
AED 729 total
includes taxes & fees
16 Jun - 17 Jun
JW Marriott Panama
Exterior
W Panama
5.0 star property
8.8 out of 10, Excellent, (989)
"Nice place to stay in Panama"
The price is AED 621
AED 673 total
includes taxes & fees
7 Jun - 8 Jun
W Panama
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Pool
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1001)
"The only place I stay when visiting or passing thru the city.."
The price is AED 528
AED 580 total
includes taxes & fees
14 Jun - 15 Jun
Marriott Panama Hotel
Exterior detail
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (221)
"Staff was extremely friendly and helpful. Everything was perfect and beautiful. Caleta restaurant served highly quality and delicious meals!"
The price is AED 1,074
AED 1,182 total
includes taxes & fees
6 Jun - 7 Jun
Sofitel Legend Casco Viejo, Panama City
Room
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, (873)
"excellent condition, great service and staff"
The price is AED 550
AED 605 total
includes taxes & fees
26 May - 27 May
Las Americas Golden Tower Panama
Pool
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (267)
"Nice"
The price is AED 186
AED 205 total
includes taxes & fees
23 Jun - 24 Jun
Hospedium Princess Hotel Panama
Exterior
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1002)
"."
The price is AED 468
AED 515 total
includes taxes & fees
24 May - 25 May
Ramada Plaza By Wyndham Panama Punta Pacífica
Outdoor pool
Euro Hotel
3.0 star property
7.6 out of 10, Good, (523)
"The hotel was well worth the money I paid. Restaurant was nice for breakfast. The hotel was clean and staff was friendly. "
The price is AED 157
AED 173 total
includes taxes & fees
22 Jun - 23 Jun
Euro Hotel
Pool
AC Hotel by Marriott Panama City
3.5 star property
9.0 out of 10, Wonderful, (414)
"Hotel muy bien ubicado, staff muy amable y con una ubicación excelente muy cerca de Vía España."
The price is AED 350
AED 380 total
includes taxes & fees
14 Jun - 15 Jun
AC Hotel by Marriott Panama City
Rooftop pool
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, (684)
"Best place to stay in the old town."
The price is AED 1,094
AED 1,203 total
includes taxes & fees
24 May - 25 May
Central Hotel Panama Casco Viejo
Outdoor pool
Summit Rainforest & Golf Resort
4.0 star property
8.4 out of 10, Very Good, (1001)
"The hotel is clean , food isn’t good,"
The price is AED 255
AED 280 total
includes taxes & fees
24 May - 25 May
Summit Rainforest & Golf Resort
Exterior
Holiday Inn Panama Distrito Financiero, an IHG Hotel
4.0 star property
8.8 out of 10, Excellent, (1001)
"All "
The price is AED 298
AED 368 total
includes taxes & fees
25 May - 26 May
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Sundeck
Hotel Coral Suites
3.5 star property
8.8 out of 10, Excellent, (959)
"staff was great"
The price is AED 279
AED 307 total
includes taxes & fees
24 May - 25 May
Hotel Coral Suites
Room
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1000)
"The best parts were cleanliness, and one of the best restaurants he 5th floor. The food was outstanding. "
The price is AED 732
AED 805 total
includes taxes & fees
22 Jun - 23 Jun
Bristol Panama, a Registry Collection Hotel
Exterior
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (323)
"Nos encantó, muy cómodas habitaciones, muy bien equipadas, todo funcionó muy bien, excelente trato, las encargadas de limpieza muy amables. Excelente ubicación, sin duda de ahora en adelante será nuestra mejor opción cuando viajemos a Panamá."
The price is AED 496
AED 540 total
includes taxes & fees
8 Jun - 9 Jun
Residence Inn by Marriott Panama City
Exterior
Torres de Alba Hotel & Suites
3.5 star property
8.8 out of 10, Excellent, (362)
"Washer and dryer in too "
The price is AED 346
AED 380 total
includes taxes & fees
24 May - 25 May
Torres de Alba Hotel & Suites
Pool
Marriott Executive Apartments Panama City, Finisterre
4.0 star property
8.8 out of 10, Excellent, (509)
"Pool, gym and sauna are really nice. Healthy breakfast options. Nice and spacious rooms. Friendly staff"
The price is AED 350
AED 380 total
includes taxes & fees
7 Jun - 8 Jun
Marriott Executive Apartments Panama City, Finisterre
Terrace/patio
Hotel Ojos del Rio
3.5 star property
8.2 out of 10, Very Good, (582)
"Verynice place "
The price is AED 184
AED 203 total
includes taxes & fees
24 May - 25 May
Hotel Ojos del Rio
Aerial view
Gamboa Rainforest Reserve
3.5 star property
7.6 out of 10, Good, (538)
"Breathtaking and incredible experience, the staff go above and beyond. If you are vegan make sure to let the buffet know when you arrive and they make every accommodation."
The price is AED 459
AED 505 total
includes taxes & fees
30 May - 31 May
Gamboa Rainforest Reserve
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Other neighborhoods around San Francisco

Hotels in top Panama City neighborhoods Learn more about San Francisco

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

How many hotels will I find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 200 San Francisco hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.

What is there to do in this Panama City neighborhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Multicentro Panama, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Omar Torrijos Recreational Park are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Panama Canal Murals, Colonial Religious Art Museum, and Bingo 90. When you're sightseeing in Panama City, Pacific Center and Soho City Center are also worth a stop.

Recent reviews of San Francisco hotels