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Compare 1,572 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1005)
"Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city."
United States
MICHELE
Central Hotel Panama Casco Viejo

Hotel Coral Suites

3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1003)
"Great place for the price. "
United States
Ryan
The price is AED 255
AED 280 total
includes taxes & fees
24 Nov - 25 Nov
Hotel Coral Suites

La Concordia Boutique Hotel

4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (193)
"The staff was very friendly and supportive. The room was spectacular! It was beautifully decorated and very clean. It was just a delight to stay in this lovely hotel!"
United States
Madelaine
La Concordia Boutique Hotel

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very Good, (1004)
"Staff very friendly, clean room, amazing food&drinks"
United States
Ashley Ethel
The price is AED 611
AED 672 total
includes taxes & fees
14 Dec - 15 Dec
The Westin Playa Bonita Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1004)
"Very beautiful room was spotless, and staff was very good with customer service"
United States
Anthony
The price is AED 629
AED 692 total
includes taxes & fees
6 Dec - 7 Dec
Waldorf Astoria Panama

TRYP by Wyndham Panamá Centro

3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1010)
"Staff was helpful, room was clean and I enjoyed my stay. "
United States
Lystra
The price is AED 283
AED 311 total
includes taxes & fees
8 Dec - 9 Dec
TRYP by Wyndham Panamá Centro

Gamboa Rainforest Reserve

3.5 star property
Colon
7.8 out of 10, Good, (656)
"We had a lovely stay, the views and tranquility of the place was my favorite part."
United States
Rebecca
The price is AED 372
AED 418 total
includes taxes & fees
24 Nov - 25 Nov
Gamboa Rainforest Reserve

Principe Hotel and Suites

3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1560)
"Clean from affordable pleasant staff was very nice stay "
United States
Iris
The price is AED 184
AED 202 total
includes taxes & fees
7 Dec - 8 Dec
Principe Hotel and Suites

Ramada Panama Centro Via Argentina

3.0 star property
Bella Vista
7.4 out of 10, Good, (264)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is AED 219
AED 240 total
includes taxes & fees
24 Nov - 25 Nov
Ramada Panama Centro Via Argentina

Hospedium Princess Hotel Panama

3.5 star property
Bella Vista
7.6 out of 10, Good, (681)
"The breakfast was great, I love the pool."
United States
Estefani
The price is AED 204
AED 224 total
includes taxes & fees
25 Nov - 26 Nov
Hospedium Princess Hotel Panama

Riande Aeropuerto Hotel & Casino

4.0 star property
Tocumen
8.6 out of 10, Excellent, (1889)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is AED 459
AED 505 total
includes taxes & fees
24 Nov - 25 Nov
Riande Aeropuerto Hotel & Casino

Novotel Panama City

4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1014)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is AED 331
AED 364 total
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City

Aloft Panama

3.5 star property
San Francisco
8.6 out of 10, Excellent, (881)
"Great staff"
United States
RENE
The price is AED 430
AED 473 total
includes taxes & fees
30 Nov - 1 Dec
Aloft Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1007)
"great stay when in PTY"
United States
Fernando
The price is AED 663
AED 730 total
includes taxes & fees
7 Dec - 8 Dec
Bristol Panama, a Registry Collection Hotel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (632)
"Beautiful property. Excellent lunch, fish tacos were amazing. "
United States
Marc
The price is AED 851
AED 936 total
includes taxes & fees
29 Nov - 30 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Plaza Paitilla Inn Hotel

3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2143)
"Very nice hotel, all amenities met our needs. "
Canada
gordon
The price is AED 457
AED 502 total
includes taxes & fees
24 Nov - 25 Nov
Plaza Paitilla Inn Hotel

Hotel San Felipe

4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (234)
"Really nice staff and property is in amazing location "
United States
Michael
The price is AED 446
AED 491 total
includes taxes & fees
24 Nov - 25 Nov
Hotel San Felipe

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1010)
"It was very clean good friendly staff good food i really love there goong back next time "
United States
Sylvester Keith
The price is AED 403
AED 443 total
includes taxes & fees
7 Dec - 8 Dec
Courtyard by Marriott Panama Metromall

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (249)
"Many shops and restaurants nearby and the hotel is located in a beautiful area "
United States
Jerry
The price is AED 1,140
AED 1,253 total
includes taxes & fees
26 Nov - 27 Nov
Hotel La Compañía Casco Antiguo

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1009)
"Spotless, friendly and great food. Great pools a restaurants. "
Canada
David
The price is AED 878
AED 966 total
includes taxes & fees
10 Dec - 11 Dec
JW Marriott Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Santa Clara attractions

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

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Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Waldorf Astoria Panama and Megapolis Hotel Panamá. See all available top hotels, or vacation rentals in Santa Clara.
What's the top vacation rental in Santa Clara?
Panama View House – A Hilltop Retreat with Stunning Canal Views: This vacation home rental outside of Santa Clara has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1564 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.

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