Find hotels in Santa Clara from AED 81

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Compare 1,490 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (962)
"Love the location and the restaurant inside the hotel was phenomenal."
The price is AED 750
AED 825 total
includes taxes & fees
8 Aug - 9 Aug
Central Hotel Panama Casco Viejo

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1003)
"Great location "
The price is AED 337
AED 371 total
includes taxes & fees
24 Aug - 25 Aug
TRYP by Wyndham Panamá Centro

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1008)
"Very nice hotel and servise excellent."
The price is AED 566
AED 622 total
includes taxes & fees
15 Aug - 16 Aug
The Westin Playa Bonita Panama

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1892)
"Great place to stay while overnight in Panama"
The price is AED 491
AED 540 total
includes taxes & fees
7 Aug - 8 Aug
Riande Aeropuerto Hotel & Casino

Hotel Coral Suites

3.5 star property
9.0 out of 10, Wonderful, (1003)
"Nice Hotel "
The price is AED 255
AED 280 total
includes taxes & fees
6 Aug - 7 Aug
Hotel Coral Suites

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1001)
"Lovely stay "
The price is AED 790
AED 869 total
includes taxes & fees
23 Aug - 24 Aug
Waldorf Astoria Panama

Hospedium Princess Hotel Panama

3.5 star property
7.6 out of 10, Good, (572)
"Nice clean ambiance"
The price is AED 159
AED 175 total
includes taxes & fees
10 Aug - 11 Aug
Hospedium Princess Hotel Panama

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1424)
"Great Hotell , super location safe "
The price is AED 215
AED 236 total
includes taxes & fees
6 Aug - 7 Aug
Principe Hotel and Suites

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (830)
"Great location "
The price is AED 423
AED 465 total
includes taxes & fees
15 Aug - 16 Aug
Aloft Panama

Ramada Panama Centro Via Argentina

3.0 star property
7.4 out of 10, Good, (245)
"Normally dont do budget hotels but this place was very good for the price and a proper breakfast."
The price is AED 218
AED 240 total
includes taxes & fees
6 Aug - 7 Aug
Ramada Panama Centro Via Argentina

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1006)
"This was a amazing property extremely clean very hospitable"
The price is AED 736
AED 809 total
includes taxes & fees
5 Sep - 6 Sep
Bristol Panama, a Registry Collection Hotel

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1008)
"Great value great rooms and breakfast "
The price is AED 347
AED 382 total
includes taxes & fees
24 Aug - 25 Aug
Novotel Panama City

SAND DIAMOND HOTEL

3.0 star property
8.4 out of 10, Very Good, (170)
"The staff is top tier"
The price is AED 437
AED 481 total
includes taxes & fees
6 Aug - 7 Aug
SAND DIAMOND HOTEL

Gamboa Rainforest Reserve

3.5 star property
7.8 out of 10, Good, (634)
"Great hotel with many tours to enjoy the Rainforest"
The price is AED 395
AED 447 total
includes taxes & fees
12 Aug - 13 Aug
Gamboa Rainforest Reserve

Exe Oriental Panama

4.0 star property
8.0 out of 10, Very Good, (1000)
"Nice hotel. Good price. Disappointed that they charge for the 2 water bottles in the room, but still a good value hotel option."
The price is AED 235
AED 259 total
includes taxes & fees
9 Aug - 10 Aug
Exe Oriental Panama

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (998)
"Lovely hotel "
The price is AED 467
AED 513 total
includes taxes & fees
29 Aug - 30 Aug
Megapolis Hotel Panamá

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1003)
"I really enjoyed my stay there. "
The price is AED 459
AED 505 total
includes taxes & fees
12 Aug - 13 Aug
Courtyard by Marriott Panama Metromall

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (593)
"The staff was very friendly. "
The price is AED 780
AED 858 total
includes taxes & fees
15 Aug - 16 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
8.8 out of 10, Excellent, (1009)
"Really good experience. Staff was very friendly and helpful. "
The price is AED 261
AED 307 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Panama Distrito Financiero by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

Culebra Cut

Culebra Cut

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history, and more!

Top Santa Clara Hotel Reviews

Frequently asked questions

What's the best place for a stay in Santa Clara?

Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Dreams Playa Bonita Panama - All Inclusive and Sheraton Grand Panama. See all available top hotels, or vacation rentals in Santa Clara.

What's the top vacation rental in Santa Clara?

Panama View House – A Hilltop Retreat with Stunning Canal Views: This vacation home rental outside of Santa Clara has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Clara.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.

What's the best place to stay near Culebra Cut?

Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.

What is staying in Santa Clara like?

Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1484 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.

What is there to see in Santa Clara?

A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.

What's the seasonal weather like in Santa Clara?

The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.