A large brick church with two bell towers and palm trees in front.

Santa Cruz de la Sierra Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Cruz de la Sierra vacation rentals

1. Plaza Sandra

Plaza Sandra
3.0 star property
Trujillo
9.6 out of 10, Exceptional, (58 reviews)
"Easy to follow check in instructions. Parking on the street nearby. Beautiful property right in the old town. Highly recommended!"
United States
Ismael
The price is AED 231
AED 254 total
includes taxes & fees
14 Oct - 15 Oct
Plaza Sandra

2. Plaza Mayor Trujillo Rooms

Plaza Mayor Trujillo Rooms
Trujillo
The price is AED 151
AED 151 total
includes taxes & fees
28 Sep - 29 Sep
Plaza Mayor Trujillo Rooms

3. Plaza Mayor Trujillo Rooms

Plaza Mayor Trujillo Rooms
Trujillo
The price is AED 151
AED 151 total
includes taxes & fees
27 Sep - 28 Sep
Plaza Mayor Trujillo Rooms

4. Tictágora House: House 1

Tictágora House: House 1
Plasenzuela
The price is AED 4,200
AED 4,759 total
includes taxes & fees
25 Sep - 26 Sep
Tictágora House: House 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz de la Sierra Hotel Reviews

Frequently asked questions

Can I find vacation rentals in Santa Cruz de la Sierra?

Yes, there are vacation rentals close to top sights in Santa Cruz de la Sierra, or you can select a more remote option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Santa Cruz de la Sierra has to offer?

Rural house with swimming pool El Huerto del Olivo, Plasenzuela, Trujillo, Cáceres: This vacation home near Santa Cruz de la Sierra is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop, and a microwave.

What can I see and do in Santa Cruz de la Sierra?

While exploring the area, visit the sights like Plaza Mayor, Church of Santa Maria la Mayor Trujillo, and Pizarro House Museum. In the larger area, you’ll find Trujillo Castle and Juan Pizarro de Orellana Palace.

What are vacation rentals like in Santa Cruz de la Sierra?

Vacation rentals are privately owned properties you can book for several days or longer in Santa Cruz de la Sierra. Vacation rentals feature amenities like laundry facilities and kitchens so your stay will be comfortable. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.