Santa Cruz Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AED 148 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

3.5 out of 5
# 37-40 Calle 9A Medellín
Fully refundable
The price is AED 312 per night from Feb 10 to Feb 11
AED 312
AED 312 total
10 Feb - 11 Feb
9/10 Wonderful! (447 reviews)
Espectacular

Reviewed on 7 February 2026

Calle Flora Hotel by Jalo
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is AED 286 per night from Mar 8 to Mar 9
AED 286
AED 286 total
8 Mar - 9 Mar
9/10 Wonderful! (1,167 reviews)
Clean well appointed room, amazing staff so friendly and kind, great pool and gym, lovely breakfast with great views and super bar and food. Seriously one of the best hotel experiences I ever had. Special thanks to Camilo, Johnathan, Juliet y Laura. Xx

Reviewed on 5 February 2026

Heiss Hotel By Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (1,833 reviews)
Awsome

Reviewed on 1 February 2026

Get rates
Hotel Dorado La 70
See all 4,163 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How do I find cheap flights to Santa Cruz that have flexible change policies?
At Expedia, we've been channeling our inner acrobat to offer you the most flexible airfares on the market. Just mark the "No change fee" box right under the filter heading "Flexible change policies" to find your ideal flight to Santa Cruz.
How can I find cheap tickets to Santa Cruz?
An useful strategy for scoring cheap airfares is to be flexible with your travel dates. Begin with searching for your flight to Santa Cruz, then click on the "flexible dates" link to compare prices for nearby days. Another helpful hint? Book well ahead of time. For an idea of fares, was the best price for a flight to Santa Cruz in the last seven days.
How much is a flight to Santa Cruz?
In the last seven days, return airfares to Santa Cruz sold from just and reached a maximum of . For one-way trips leaving (), the lowest amount paid during this same period was only .
When is the cheapest time to fly to Santa Cruz?
If you're not fixed on your travel dates to Santa Cruz, depart earlier in the week. The most affordable day to take off is normally Tuesday, followed by Monday. Saturday is typically the priciest day, with lots of vacationers preferring to fly on weekends.
How much is a plane ticket to Santa Cruz?
In the last seven days, fares to Santa Cruz varied from to .
What months are the cheapest to book a flight to Santa Cruz?
To land a low-cost flight to Santa Cruz, try to book during the month of February when airfares are at their cheapest. When's the most expensive time? In the USA, it's the month of December.