
Santa Cruz Vacations
Book a Hotel + Flight together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to AED 148 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Find the Best Santa Cruz Vacation Packages
Santa Cruz Hotel Deals

Santa Cruz Plaza
Plaza De Armas 286, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
The price is AED 340 per night from Jun 1 to Jun 2
AED 340
AED 340 total
1 Jun - 2 Jun
8.6/10 Excellent! (309 reviews)
"It was great, spa, sauna and heated pool was nice touch"
Reviewed on 19 April 2025

Hotel Cava Colchagua
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
The price is AED 588 per night from May 18 to May 19
AED 588
AED 588 total
18 May - 19 May
8.8/10 Excellent! (155 reviews)
"Fun, interesting, pools ice cold, dogs barking all night. Still you don’t want to miss this opportunity."
Reviewed on 29 March 2025

Hotel Boutique Vendimia Premium
Ismael Valdes 92, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
The price is AED 262 per night from May 11 to May 12
AED 262
AED 262 total
11 May - 12 May
Quirky but nice
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different."
Reviewed on 5 October 2024
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Lapostolle Clos Apalta Winery
5/5(3 reviews)
You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.
Casino Colchagua
Why not roll the dice with a visit to Casino Colchagua during your visit to Santa Cruz? While in this relaxing area, you can savor the wineries and restaurants.
Colchagua Campo y Vino
5/5(1 review)
Enjoy an outing to Colchagua Campo y Vino during your stay in Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.