Santa Cruz Vacations

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Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is AED 181 per night from Feb 12 to Feb 13
AED 181
AED 181 total
12 Feb - 13 Feb
9.4/10 Exceptional! (85 reviews)
Awesome

Reviewed on 6 February 2026

Ibis Santa Cruz DE LA Sierra
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
The price is AED 465 per night from Feb 27 to Feb 28
AED 465
AED 465 total
27 Feb - 28 Feb
9/10 Wonderful! (213 reviews)
Muy bien exelente

Reviewed on 9 December 2025

Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
The price is AED 529 per night from Feb 22 to Feb 23
AED 529
AED 529 total
22 Feb - 23 Feb
8.8/10 Excellent! (357 reviews)
Welcoming clean rooms, friendly staff, continental breakfast with natural drinks

Reviewed on 29 January 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
See all 293 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz

Ventura Mall

During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.

Ventura Mall

Guembe Biocenter

Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops.

Guembe Biocenter

Santa Cruz Zoo

Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.

Santa Cruz Zoo

Frequently asked questions

How do I find cheap flights to Santa Cruz that have flexible change policies?
We get that travel arrangements can change very quickly, so locking in a flexible airfare with Expedia is always a clever idea. Simply click on "No change fee" directly below the "Flexible change policies" filter. Your low-cost, flexible flight to Santa Cruz is only a few clicks away.
Which airlines fly to Santa Cruz?
BoA is a widely known carrier servicing Santa Cruz. Search for a ticket to Viru Viru Intl. Airport (VVI) and you'll have 30 BoA flights every month to pick from.
How can I find cheap tickets to Santa Cruz?
One of the best ways to get a hold of cheap tickets to Santa Cruz is to be flexible with your travel dates. Search for your flights, then click "flexible dates" at the top of your results. It will reveal the cheapest prices for nearby days. The lowest price for a flight to Santa Cruz in the last seven days was . Booking in advance will usually help you pick up an even bigger bargain.
How much is a flight to Santa Cruz?
There were loads of budget-friendly fares up for grabs in the last seven days, with the price of a return flight to Santa Cruz varying between and . Many lucky travelers scored one-way tickets from () for as low as .
What are the most popular airports to fly into in Santa Cruz?
Fly into Viru Viru Intl. Airport (VVI) and experience all that Santa Cruz has to offer. As the region's main point of entry, around 30 flights land here each month.
When is the cheapest time to fly to Santa Cruz?
If you can be flexible with what day you travel to Santa Cruz, depart earlier in the week. The most economical day to take off is normally Tuesday, followed by Monday. Saturday is typically the most expensive day, with lots of vacationers opting to take off on the weekend.
How much is a plane ticket to Santa Cruz?
In the last seven days, plane fares to Santa Cruz fluctuated between and . Prices tend to go up over time, so book a great deal today.
What months are the cheapest to book a flight to Santa Cruz?
February is the most affordable month to secure a seat for your Santa Cruz escape. Tickets are priciest throughout the month of December, so avoid this time if possible.