Santa Fe Vacations

Book a Hotel + Flight together to unlock savings

Photo by Ministerio de Turismo de la Nación/Argentina Travel

  • Plan, book, travel with confidence

  • Better together

    Save up to AED 148 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santa Fe Vacation Packages

Santa Fe Hotel Deals

InterTower Hotel

InterTower Hotel

4 out of 5
San Jeronimo 2779, Santa Fe, Santa Fe
Fully refundableReserve now, pay when you stay
The price is AED 314 per night from Dec 8 to Dec 9
AED 314
AED 314 total
8 Dec - 9 Dec
8.8/10 Excellent! (207 reviews)
Everything was perfect!!

Reviewed on 4 November 2025

InterTower Hotel
Los Silos Hotel

Los Silos Hotel

4 out of 5
Dique I Puerto Santa Fe, La Ribera Shopping, Santa Fe, Santa Fe
Fully refundableReserve now, pay when you stay
The price is AED 428 per night from Nov 16 to Nov 17
AED 428
AED 428 total
16 Nov - 17 Nov
9.2/10 Wonderful! (27 reviews)
Muy original, un hotel construido en un viejo Silo

Reviewed on 31 March 2024

Los Silos Hotel
Castelar Hotel Santa Fe

Castelar Hotel Santa Fe

3 out of 5
25 de Mayo 2349, Santa Fe, Santa Fe
Fully refundableReserve now, pay when you stay
The price is AED 222 per night from Dec 3 to Dec 4
AED 222
AED 222 total
3 Dec - 4 Dec
7.2/10 Good! (88 reviews)
Great area for walking and dining. Friendly and helpful staff.

Reviewed on 12 July 2025

Castelar Hotel Santa Fe
See all 65 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Fe

Church and Convent of San Francisco

Church and Convent of San Francisco

Church and Convent of San Francisco is just one of the places to see in Santa Fe, so why not enjoy the other things to explore during your travels? Discover the area's museums and monuments.

Church and Convent of San Francisco

April 15 Stadium

Catch an event at April 15 Stadium during your trip to Santa Fe. Experience the area's live music and festivals.

April 15 Stadium

National University of the Littoral

Take a campus tour or just explore the area of National University of the Littoral, during your travels in Santa Fe. Experience the area's live music and festivals.

National University of the Littoral

Frequently asked questions

How do I find cheap flights to Santa Fe that have flexible change policies?
Search for your affordable airfares to Santa Fe, then mark the "No change fee" box directly under the "Flexible change policies" subheading. It really is that easy. We get that things can change and flexibility is essential, so you can book with confidence with Expedia.
How can I find cheap tickets to Santa Fe?
One of the easiest ways to nab cheap tickets to Santa Fe is to be flexible with your dates. Search for your flights, then click "flexible dates" at the top of your results. It'll reveal the cheapest prices for nearby days. The lowest price for a flight to Santa Fe in the last seven days was . Booking in advance will usually help you score an even bigger bargain.
How much is a flight to Santa Fe?
You could have picked up a return ticket to Santa Fe from anywhere between and in the last seven days. For one-way journeys departing from (), the lowest price during this time was just .
When is the cheapest time to fly to Santa Fe?
Fly out on a Tuesday to increase your chances of nabbing the cheapest flight to Santa Fe. Mondays are usually the second most affordable day to depart. Saturday is normally the priciest day to fly anywhere.
How much is a plane ticket to Santa Fe?
In the last seven days, plane tickets to Santa Fe ranged between and . Prices depend on multiple things, particularly the departure time, cabin class, airline and when you make your booking.
What months are the cheapest to book a flight to Santa Fe?
February is the most affordable month to purchase a seat for your Santa Fe vacation. Fares cost the most throughout the month of December, so steer clear of this time if possible.