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Compare 35 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Frequently asked questions

Where can I learn more about changing or cancelling my trip to Santa Mission?

For more details about rescheduling or cancelling your trip to Santa Mission, click here.

What's the seasonal weather like in Santa Mission?

The hottest months are usually September and October with an average temp of 80°F, while the coldest months are January and February with an average of 77°F. The rainiest months in Santa Mission are June, May, July, and December, with each month seeing an average of 12 inches of rainfall.

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