An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Find Business Hotels in Santee, SC

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Check availability on Santee Business Hotels

Tonight
26 Sep - 27 Sep
Tomorrow
27 Sep - 28 Sep
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

Our top choices for Santee business-friendly hotels

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)
Lobby
Free daily continental breakfast
Exterior

1. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Yomerys
AED 275
AED 306 total
includes taxes & fees
27 Sep - 28 Sep
Baymont by Wyndham Santee
Exterior
Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi (surcharge)
Lobby
Free daily continental breakfast

2. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Johnny
AED 437
AED 485 total
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus Santee Inn
Children's activities
Point of interest
Exterior
Exterior

3. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
United States
Dennis
AED 404
AED 448 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Santee by IHG
Lobby
Exterior
Desk, blackout drapes, soundproofing, iron/ironing board (on request)
Seasonal outdoor pool

4. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
United States
William
AED 234
AED 260 total
includes taxes & fees
4 Oct - 5 Oct
Super 8 by Wyndham Santee/I-95
Free daily full breakfast
Desk, WiFi (free), bed sheets
Lobby
Lobby

5. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
United States
Mark
AED 227
AED 272 total
includes taxes & fees
26 Oct - 27 Oct
Quality Inn & Suites Santee I-95
Lobby lounge
Free daily continental breakfast
In-room safe, desk, laptop workspace, iron/ironing board
Vending machine

6. Red Roof Inn Santee

Red Roof Inn Santee
Santee
United States
Tiffany
AED 231
AED 257 total
includes taxes & fees
29 Sep - 30 Sep
Red Roof Inn Santee
Lobby
Meeting facility
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Property amenity

7. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
Santee
United States
Stevenson
AED 298
AED 330 total
includes taxes & fees
27 Sep - 28 Sep
Ramada by Wyndham Santee I-95
Lobby lounge
Property amenity
Reception
Property amenity

8. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
Orangeburg
United States
Percy
AED 372
AED 412 total
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn by Marriott Orangeburg
Desk, laptop workspace, iron/ironing board, WiFi (free)
Exterior
BBQ/picnic area
Lobby

9. SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
Manning
United States
Bruce
AED 331
AED 368 total
includes taxes & fees
27 Sep - 28 Sep
SureStay Hotel by Best Western Manning
Snack bar
Lobby
Lobby
Lobby

10. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
Orangeburg
United States
Deborah
AED 419
AED 465 total
includes taxes & fees
11 Oct - 12 Oct
Tru by Hilton Orangeburg
View all properties

Top Santee Hotel Reviews

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

8/10 Good
"Very convenient"
David 1-night trip
Posted 2 days ago
Hampton Inn Santee-I-95
Best Western Plus Santee Inn

Best Western Plus Santee Inn

10/10 Excellent
"Nice location and very convenient parking, Breakfast was very good."
Johnny 1-night trip
Posted 3 days ago
Best Western Plus Santee Inn
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

10/10 Excellent
"Room was very clean and large. Staff were very friendly and enjoyed the breakfast."
Rita 1-night trip
Posted 12 days ago
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Great service"
Kunjan 1-night trip
Posted 2 weeks ago
Travelodge by Wyndham Santee