An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Find Business Hotels in Santee, SC

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Check availability on Santee Business Hotels

Tonight
12 Sep - 13 Sep
Tomorrow
13 Sep - 14 Sep
Next weekend
18 Sep - 20 Sep
In two weeks
25 Sep - 27 Sep

Our top choices for Santee business-friendly hotels

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)
Lobby
Free daily continental breakfast
Exterior

1. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Yomerys
AED 294
AED 326 total
includes taxes & fees
14 Sep - 15 Sep
Baymont by Wyndham Santee
Exterior
Lobby
Lobby sitting area
Standard Room, 2 Queen Beds, Non Smoking, Jetted Tub | Desk, laptop workspace, iron/ironing board, WiFi (surcharge)

2. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Bonnie
AED 406
AED 451 total
includes taxes & fees
20 Sep - 21 Sep
Best Western Plus Santee Inn
Children's activities
Exterior
In-room safe, desk, laptop workspace, soundproofing
Exterior

3. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
United States
Dennis
AED 404
AED 448 total
includes taxes & fees
20 Sep - 21 Sep
Holiday Inn Santee by IHG
Free daily full breakfast
Desk, WiFi (free), bed sheets
Lobby
Lobby

4. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
United States
Will
AED 212
AED 255 total
includes taxes & fees
20 Sep - 21 Sep
Quality Inn & Suites Santee I-95
Lobby
Lobby
Exterior
Seasonal outdoor pool

5. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
United States
William
AED 234
AED 260 total
includes taxes & fees
20 Sep - 21 Sep
Super 8 by Wyndham Santee/I-95
Exterior
Lobby lounge
In-room safe, desk, laptop workspace, iron/ironing board
In-room safe, desk, laptop workspace, iron/ironing board

6. Red Roof Inn Santee

Red Roof Inn Santee
Santee
United States
Tiffany
AED 231
AED 257 total
includes taxes & fees
16 Sep - 17 Sep
Red Roof Inn Santee
Lobby
Property amenity
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Fitness facility

7. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
Santee
United States
Stevenson
AED 259
AED 288 total
includes taxes & fees
27 Sep - 28 Sep
Ramada by Wyndham Santee I-95
Lobby lounge
Property amenity
Property amenity
Property amenity

8. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
Orangeburg
United States
Percy
AED 387
AED 430 total
includes taxes & fees
17 Sep - 18 Sep
Fairfield Inn by Marriott Orangeburg
Front of property
32-inch TV with satellite channels
Lobby
Free daily continental breakfast

9. Peach Tree Inn

Peach Tree Inn
St. George
United States
Linda
AED 237
AED 256 total
includes taxes & fees
1 Oct - 2 Oct
Peach Tree Inn
Snack bar
Free daily buffet breakfast
Lobby
Lobby

10. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
Orangeburg
Canada
Andrew
AED 419
AED 465 total
includes taxes & fees
27 Sep - 28 Sep
Tru by Hilton Orangeburg
View all properties

Top Santee Hotel Reviews

Baymont by Wyndham Santee

Baymont by Wyndham Santee

8/10 Good
"Comfortable rooms good showers. Definitely ok for a night while traveling"
Robert 1-night trip
Posted 9 hours ago
Baymont by Wyndham Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Great service"
Kunjan 1-night trip
Posted 13 hours ago
Travelodge by Wyndham Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 1 month ago
Ramada by Wyndham Santee I-95