An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Find Business Hotels in Santee, SC

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Check availability on Santee Business Hotels

Tonight
5 Oct - 6 Oct
Tomorrow
6 Oct - 7 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Santee business-friendly hotels

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.
A gym with treadmills, weight machines, and a wall of dumbbells.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".

1. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
United States
sandra
AED 401
AED 445 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Santee-I-95
A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A reception desk with a wooden panel wall and a circular decorative piece above it.
A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.

2. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
United States
Melissa
AED 509
AED 565 total
includes taxes & fees
11 Oct - 12 Oct
Fairfield Inn & Suites by Marriott Santee
A hotel entrance with a sign reading "Best Western PLISS."
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.

3. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Johnny
AED 481
AED 534 total
includes taxes & fees
14 Oct - 15 Oct
Best Western Plus Santee Inn
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A hotel room with two beds, a desk, and a large window with a view.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A modern lobby with a blue sofa, teal chairs, and a wooden table.

4. Tru By Hilton Santee

Tru By Hilton Santee
Santee
United States
Connor
AED 372
AED 412 total
includes taxes & fees
11 Oct - 12 Oct
Tru By Hilton Santee
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.
A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.
A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.
A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.

5. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Cindy
AED 294
AED 326 total
includes taxes & fees
6 Oct - 7 Oct
Baymont by Wyndham Santee
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

6. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
United States
santa
AED 378
AED 419 total
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn & Suites Santee
A water park with a pool, slides, and umbrellas.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A modern lounge area with seating, tables, and a fireplace.

7. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
United States
roderick
AED 400
AED 444 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Santee by IHG
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A motel with a brick facade, a covered entrance, and a satellite dish.
A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
United States
Joshua
AED 235
AED 261 total
includes taxes & fees
11 Oct - 12 Oct
Travelodge by Wyndham Santee
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A two-story building with a beige facade, large windows, and a central entrance.
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with large windows.

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
United States
William
AED 234
AED 260 total
includes taxes & fees
12 Oct - 13 Oct
Super 8 by Wyndham Santee/I-95
A vending machine with various snacks and drinks, including Pepsi, and a water dispenser labeled 'Ice Cubes'.
A hotel room with a dining area, a TV screen displaying 'Free Wi-Fi All Rooms,' and a kitchen area.
A hotel room with a bed, bedside tables, a desk, a mirror, and a wall-mounted TV.
A hotel lobby with a reception desk, a dining area with tables and chairs, and a view of the outside.

10. Red Roof Inn Santee

Red Roof Inn Santee
Santee
United States
Tiffany
AED 231
AED 257 total
includes taxes & fees
11 Oct - 12 Oct
Red Roof Inn Santee
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Top Santee Hotel Reviews

Baymont by Wyndham Santee

Baymont by Wyndham Santee

8/10 Good
"Clean, comfortable and friendly."
Dorothy 1-night trip
Posted 18 hours ago
Baymont by Wyndham Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

8/10 Good
"Good cleaning room, good ac"
Benjamin 2-night trip
Posted 7 days ago
Travelodge by Wyndham Santee