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Check prices for these dates

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Santee hotels

A spacious kitchen with a large island, modern pendant lights, and a ceiling fan.
Two people sitting on Adirondack chairs facing a lake, with picnic tables and benches in the background.
A spacious room with wooden walls and ceiling, featuring a large chandelier, multiple windows, and a central seating area with tables and chairs.
A modern kitchen with stainless steel appliances, dark wood cabinets, and a tiled floor.

1. Lewis and Clark Resort

Lewis and Clark Resort
Yankton
United States
Jeff
AED 417
AED 440 total
includes taxes & fees
1 Nov - 2 Nov
Lewis and Clark Resort
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Top Santee Hotel Reviews

Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.

Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.

10/10 Excellent
"Very nice house and host was very good. saw deer and turkeys from the deck. Close to missouri river and restaurants close by."
Randy A. 2-night trip
Posted 2 days ago
Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.
Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"Had a great time except for the neighbors keeping us up until 2-3:00 am. Kitchen floor was not very clean."
Maranda 2-night trip
Posted 3 days ago
Lewis and Clark Resort
Haven by the Lake

Haven by the Lake

10/10 Excellent
"My children and grandchildren enjoyed the stay. Grandchildren wanted to know when they could come back to stay again. They especially loved watching the turkeys and even got close enough to get a picture of a young buck deer."
Ann K. 2-night trip
Posted 2 weeks ago
Haven by the Lake
Charming Lake House within Walking Distance from Lake

Charming Lake House within Walking Distance from Lake

10/10 Excellent
"It was a great place to stay , it was nice the kids had their own area to hang out"
Eugenia D. 3-night trip
Posted 1 month ago
Charming Lake House within Walking Distance from Lake
Hunters & outdoor lovers charming 4-bedrm house - best Lewis & Clark lake view!

Hunters & outdoor lovers charming 4-bedrm house - best Lewis & Clark lake view!

10/10 Excellent
"The location was perfect and absolutely beautiful. The floor plan is great having the two living rooms and kitchens. We had trucks with trailers and plenty of room to turn around and park. It did seem like they were in the middle of some remodel projects. It was not a big deal but somewhat strange. We did get two different answers regarding having extra family coming to the property but not staying the night, we were also unsure on how many were going to be joining. We will definitely return to this home. It has a welcome home feeling. To be expected the bugs and spiders, we did a quick clean around the doors and wipe down when we got there. The outside cameras were no big deal for us and extra security for our toys."
patricia f. 4-night trip
Posted 1 month ago
Hunters & outdoor lovers charming 4-bedrm house - best Lewis & Clark lake view!
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

10/10 Excellent
"Everything was great!"
Brenna J. 3-night trip
Posted 1 month ago
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Fully furnished lake house with cozy spaces, full kitchen, and lake views.

10/10 Excellent
"Great location to host our company retreat! The house was spacious and offered plenty of room. Appreciated all the outdoor chairs available to use. We enjoyed sitting around the outdoor firepit at night."
Katie K. 3-night trip
Posted 1 month ago
Fully furnished lake house with cozy spaces, full kitchen, and lake views.
Lewis and Clark Lake Home/Loft for Rent/Lake View Property and Lake Access

Lewis and Clark Lake Home/Loft for Rent/Lake View Property and Lake Access

10/10 Excellent
"The view is worth it alone. The space great for all to be together. Well equipped. The location for us worked great! We hope to be back."
karla s. 3-night trip
Posted 1 month ago
Lewis and Clark Lake Home/Loft for Rent/Lake View Property and Lake Access
HotTub, PingPong, Firepit, 2 LivingRooms just .67 mi to beach

HotTub, PingPong, Firepit, 2 LivingRooms just .67 mi to beach

10/10 Excellent
"Great property! Very well stocked. Amazing decor. Quiet neighborhood. Nice spaces for a large group to spread out."
Jeanne J. 3-night trip
Posted 2 months ago
HotTub, PingPong, Firepit, 2 LivingRooms just .67 mi to beach

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive Yankton SD
AED 417
AED 440 total
1 Nov - 2 Nov
includes taxes & fees
9/10 Wonderful! (352 reviews)
Lewis and Clark Resort

Frequently asked questions

Where is the best place for a stay in Santee?
Lewis and Clark Resort, located 16.8 mi (27 km) from the heart of Santee, is a top choice for your stay based on our traveler data. Family, friendly country farm home. Enjoying peace and quiet. is another good choice for your stay in the area. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals that Santee has to offer?
Newly Remodeled Creekside Bungalow on 3 acres with Private Beach Beside Creek: This vacation home rental near Santee is located in a rural location and offers a barbecue grill, air-conditioning, and free WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about rescheduling or cancelling your trip to Santee, click here.
What is staying in Santee like?
Those traveling to Santee are sure to enjoy the sights to see and things to do. There are 68 hotels and other accommodations in the surrounding area. Find out more about Santee.
What are the top places to visit in Santee?
A favorite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Check out what more to see and do in Expedia's Santee guide.
What's the weather like in Santee?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Santee are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.