Find hotels in Santo Tomas, Mexico City from AED 127

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Check prices for these dates

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10 Dec - 11 Dec
Tomorrow
11 Dec - 12 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Santo Tomas hotels

Food and drink
Verticca Hotel

Verticca Hotel

Verticca Hotel
3.0 star property
29.6 km from Santo Tomas
9.2 out of 10, Wonderful, (241)
"Excelente Hotel"
Mexico
juan Ricardo
Verticca Hotel
Breakfast, lunch, dinner served; Mexican cuisine
Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City
4.0 star property
Historic Center, 7.2 km from Santo Tomas
9.8 out of 10, Exceptional, (2630)
"Always a great stay. Great staff, food and comfortable room."
Canada
John
The price is AED 611
AED 730 total
includes taxes & fees
14 Dec - 15 Dec
Zocalo Central & Rooftop Mexico City
Breakfast, lunch, dinner served; Mexican cuisine
Hotel Catedral

Hotel Catedral

Hotel Catedral
4.0 star property
Historic Center, 7.2 km from Santo Tomas
9.4 out of 10, Exceptional, (2595)
"The room was very clean and the location was great"
United States
Michele
The price is AED 739
AED 883 total
includes taxes & fees
11 Dec - 12 Dec
Hotel Catedral
Lobby
Hotel Bellas Artes

Hotel Bellas Artes

Hotel Bellas Artes
4.0 star property
Historic Center, 6.9 km from Santo Tomas
9.6 out of 10, Exceptional, (544)
"Very nice staff, the location is perfect, amenities definitely will consider to stay in the future "
United States
Nelson
The price is AED 321
AED 384 total
includes taxes & fees
18 Dec - 19 Dec
Hotel Bellas Artes
Lobby
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham

Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham

Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
3.5 star property
20.7 km from Santo Tomas
9.2 out of 10, Wonderful, (587)
"Great Team"
United States
Fangchu
The price is AED 207
AED 248 total
includes taxes & fees
14 Dec - 15 Dec
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
2 bars/lounges
Hotel Parque Satelite

Hotel Parque Satelite

Hotel Parque Satelite
3.0 star property
6.7 km from Santo Tomas
9.2 out of 10, Wonderful, (1001)
"Good place to stay nice and clean"
United States
guillermo
The price is AED 179
AED 215 total
includes taxes & fees
11 Dec - 12 Dec
Hotel Parque Satelite
Indoor pool, outdoor pool
Hilton Mexico City Reforma

Hilton Mexico City Reforma

Hilton Mexico City Reforma
4.5 star property
Reforma, 6.5 km from Santo Tomas
9.4 out of 10, Exceptional, (1051)
"great place . friendly staff and everything was to perfection."
United States
Adriana
The price is AED 652
AED 780 total
includes taxes & fees
1 Jan - 2 January 2026
Hilton Mexico City Reforma
Interior
Hotel Juarez

Hotel Juarez

Hotel Juarez
2.5 star property
Historic Center, 7.2 km from Santo Tomas
9.0 out of 10, Wonderful, (1787)
"Excelente hotel"
Mexico
César augusto
The price is AED 106
AED 127 total
includes taxes & fees
15 Dec - 16 Dec
Hotel Juarez
Standard Room, 2 Double Beds, Non Smoking | Pillowtop beds, in-room safe, desk, laptop workspace
Sleep Inn Ciudad de México

Sleep Inn Ciudad de México

Sleep Inn Ciudad de México
3.0 star property
17 km from Santo Tomas
8.4 out of 10, Very Good, (1006)
"Nice hotel. "
United States
Alejandra
The price is AED 254
AED 303 total
includes taxes & fees
13 Dec - 14 Dec
Sleep Inn Ciudad de México
Front of property
Historico Central Hotel

Historico Central Hotel

Historico Central Hotel
4.0 star property
Historic Center, 7.1 km from Santo Tomas
9.8 out of 10, Exceptional, (2393)
"Location was great and hotel was clean and comfortable "
United States
Daniela
The price is AED 530
AED 633 total
includes taxes & fees
18 Dec - 19 Dec
Historico Central Hotel
View from room
Hotel Punto MX

Hotel Punto MX

Hotel Punto MX
3.5 star property
Historic Center, 7.4 km from Santo Tomas
9.0 out of 10, Wonderful, (1421)
"Excellent staff and gorgeous hotel "
United States
Fernando
The price is AED 219
AED 262 total
includes taxes & fees
7 Jan - 8 January 2026
Hotel Punto MX
Deluxe Studio Suite | Minibar, desk, laptop workspace, iron/ironing board
Colmena Hotel CDMX Centro

Colmena Hotel CDMX Centro

Colmena Hotel CDMX Centro
3.0 star property
Historic Center, 7.2 km from Santo Tomas
8.6 out of 10, Excellent, (286)
"I enjoyed my stay. Nice food and location "
United States
Mike
The price is AED 233
AED 279 total
includes taxes & fees
7 Jan - 8 January 2026
Colmena Hotel CDMX Centro
Reception
Hotel & Villas Panamá

Hotel & Villas Panamá

Hotel & Villas Panamá
3.0 star property
2.5 km from Santo Tomas
8.6 out of 10, Excellent, (937)
"As in the last 14 or more visits throughout the last 11 years I am very happy with my visit and highly recommend villas Panama. safe, clean, great location, very well kept, flexible and warm staff Thank you to the staff and management. "
United States
Jose
Hotel & Villas Panamá
Deluxe Double Room | In-room safe, blackout drapes, soundproofing, iron/ironing board
Punta Alameda

Punta Alameda

Punta Alameda
2.0 star property
Downtown Mexico City, 6.9 km from Santo Tomas
9.4 out of 10, Exceptional, (202)
"Regular cleaning, friendly staff"
Canada
Mukul
Punta Alameda
Exterior
Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico
3.0 star property
Historic Center, 7.6 km from Santo Tomas
9.0 out of 10, Wonderful, (1077)
"Great location and customer services "
Canada
Hernan
The price is AED 282
AED 337 total
includes taxes & fees
5 Jan - 6 January 2026
Hampton Inn & Suites Mexico City - Centro Historico
Reception
Royal Pedregal Hotel

Royal Pedregal Hotel

Royal Pedregal Hotel
4.0 star property
Tlalpan, 20.4 km from Santo Tomas
9.0 out of 10, Wonderful, (1825)
"Excellent option if you need to be in the southern part of CDMX"
United States
Carlos
The price is AED 246
AED 294 total
includes taxes & fees
1 Jan - 2 January 2026
Royal Pedregal Hotel
Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes
Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG
3.0 star property
6 km from Santo Tomas
9.2 out of 10, Wonderful, (1040)
"Excellent stay!"
United States
Derek
The price is AED 254
AED 304 total
includes taxes & fees
5 Jan - 6 January 2026
Holiday Inn Express Mexico Basilica by IHG
Sundeck
Galeria Plaza San Jeronimo

Galeria Plaza San Jeronimo

Galeria Plaza San Jeronimo
4.0 star property
17.9 km from Santo Tomas
9.2 out of 10, Wonderful, (1005)
"Very peaceful and staff was great "
United States
Magiver
The price is AED 392
AED 468 total
includes taxes & fees
26 Dec - 27 Dec
Galeria Plaza San Jeronimo
Terrace/patio
Hotel Brasilia

Hotel Brasilia

Hotel Brasilia
3.0 star property
4.2 km from Santo Tomas
9.0 out of 10, Wonderful, (1005)
"Super clean hotel and the staff very pleasant and friendly."
United States
Emanuel
The price is AED 219
AED 261 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Brasilia
Exterior
Hotel Plaza Revolución

Hotel Plaza Revolución

Hotel Plaza Revolución
3.5 star property
6.2 km from Santo Tomas
8.8 out of 10, Excellent, (1001)
"A very walkable distance to the Historic Center"
United States
RAUL E
Hotel Plaza Revolución
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santo Tomas

Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Polanco featuring a church or cathedral, a park and heritage architecture

Polanco

Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.

La Condesa featuring cafe lifestyle

La Condesa

Fashionable and popular with young professionals, Condesa boasts international restaurants, bars, and nightclubs. Stroll along tree-lined avenues, admire Art Deco architecture, and visit landmarks like Edificio San Martín and Basurto Building.

Metropolitan Cathedral showing street scenes, heritage elements and a church or cathedral

Historic Center

Historic center with 1,550 significant buildings, the neighborhood offers museums like MUNAL and Palacio de Bellas Artes. Enjoy upscale eateries, fashionable stores, and pedestrianized streets for easy exploration.

Reforma featuring city views, a city and night scenes

Reforma

Consider a visit to Paseo de la Reforma and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Tomas Hotel Reviews

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

10/10 Excellent
"Yes"
Eduardo 1-night trip
Posted 14 hours ago
Camino Real Aeropuerto Mexico

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Frequently asked questions

What is Santo Tomas like?
Travelers will be sure to find plenty to entertain them in Mexico City's Santo Tomas neighborhood. Consider a visit to Hospital de Jesus Nazareno as part of your Santo Tomas travel plans.
If I need to cancel my hotel reservation in Santo Tomas, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to review the best options available in Santo Tomas.
Where can I learn more about changing or cancelling my trip to Santo Tomas?
For additional details about rescheduling or cancelling your trip to Santo Tomas, go to https://www.expedia.com/service/.
What is there to do around this Mexico City neighborhood?
Hospital de Jesus Nazareno is an attraction you might want to check out while you're in Santo Tomas. While you're out sightseeing, Mexico City Arena and TecnoParque are a couple of additional sights to visit in Mexico City.