São Tomé Island Vacations

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Find the Best São Tomé Island Vacation Packages

São Tomé Island Hotel Deals

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
The price is AED 792 per night from Feb 10 to Feb 11
AED 792
AED 930 total
10 Feb - 11 Feb
includes taxes & fees
8/10 Very Good! (78 reviews)
Wonderful stay, great staff, easy, relaxing delightful.

Reviewed on 9 December 2025

Pestana São Tomé
Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
8/10 Very Good! (24 reviews)
On my last night, I was locked out and couldn't open the outside door to enter the hotel. I tried to contact the hotel using the phone number provided on Expedia, but it wasn't updated. As a result, I had to stay at a friend's house for the night.

Reviewed on 7 November 2024

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Hotel Central
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
The price is AED 719 per night from Mar 11 to Mar 12
AED 719
AED 854 total
11 Mar - 12 Mar
includes taxes & fees
9.4/10 Exceptional! (62 reviews)
Staff was very friendly. Food was excellent. Room was clean and well kept.

Reviewed on 4 December 2025

Omali São Tomé – Principe Collection
See all 48 properties in São Tomé Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in São Tomé Island

São Sebastião Museum

You can spend time studying the exhibits at São Sebastião Museum during your travels in São Tomé. Wander the rainforest or discover the area's coral reefs.

São Sebastião Museum

Pico São Tomé

Commune with nature and explore the great outdoors at Pico São Tomé during your travels in Santa Catarina. Wander the rainforest or discover the area's mountain views.

Pico São Tomé

São Nicolau Waterfall

Commune with nature and explore the great outdoors at São Nicolau Waterfall during your travels in Trindade.

São Nicolau Waterfall

Frequently asked questions

How do I find cheap flights to São Tomé Island that have flexible change policies?
It's as easy as 1-2-3 with Expedia. Step 1: Enter your preferred travel dates and hit "Search." Step 2? Check the "No change fee" box below the "Flexible change policies" subheading on the left-hand side of your screen. Step 3. Bag a cheap and flexible airfare to São Tomé Island.
How can I find cheap tickets to São Tomé Island?
One of the easiest ways to score cheap tickets to São Tomé Island is to be flexible with your travel dates. Search for your flights, then click "flexible dates" above the results. You'll see the cheapest prices for nearby days. The lowest price for a flight to São Tomé Island in the last seven days was . Booking ahead will usually help you walk away with an even better deal.
How much is a flight to São Tomé Island?
In the last seven days, return flights to São Tomé Island sold for as little as and reached a maximum cost of . For one-way journeys departing from (), the lowest amount paid during this same period was just .
When is the cheapest time to fly to São Tomé Island?
Take off for São Tomé Island earlier in the week and you'll usually be rewarded with lower fares. Tuesday is generally the cheapest day to jet off, followed closely by Monday. If you'd like to avoid the priciest flights, give Saturdays a wide berth.
How much is a plane ticket to São Tomé Island?
In the last seven days, fares to São Tomé Island ranged between and . The early bird catches the worm, so land yourself a good deal today.
What months are the cheapest to book a flight to São Tomé Island?
February is the perfect month to score cheap flights to São Tomé Island. Bear in mind that the priciest time to make a booking in the U.S. isn't the middle of summer, but the festive month of December.