A dense cluster of vibrant pink azaleas in full bloom.

Semmes Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
28 Aug - 30 Aug
In two months
9 Oct - 11 Oct
In three months
6 Nov - 8 Nov
In four months
4 Dec - 6 Dec

Our top choices for Semmes vacation rentals

Smart TV

1. Charming 3-bedroom cottage with WiFi, AC nears parks and shopping

Charming 3-bedroom cottage with WiFi, AC nears parks and shopping
Mobile
9.8 out of 10, Exceptional, (9 reviews)
"The host was amazing very clean and beautiful property close to everything. The set up and welcome was great i would definitely stay again. "
United States
Welton M.
The price is AED 511
AED 951 total
includes taxes & fees
7 Sep - 8 Sep
Charming 3-bedroom cottage with WiFi, AC nears parks and shopping
Smart TV, offices

2. Modern Chic 2BR | Downtown Living & Pet-Friendly

Modern Chic 2BR | Downtown Living & Pet-Friendly
Mobile
10.0 out of 10, Exceptional, (1 review)
"We were late to check in do to a storm. We contacted the owner and they was more than understanding. They even turned the porch light on for us so when we arrived we would be able to see. This was very thoughtful . The house was clean a good layout. They had rolls of trash bags complimentary waters coffee sugar and creamer for weeks if I needed to stay longer. They had enough toilet paper dish soap laundry consumables. The had silverware plates cups coffee cups cookware to cook for a army. They...
United States
Mary B.
Modern Chic 2BR | Downtown Living & Pet-Friendly
Coffee/tea maker, fridge, microwave, oven

3. West Mobile Farmhouse Fun

West Mobile Farmhouse Fun
Mobile
West Mobile Farmhouse Fun
Outdoor dining

4. Cozy Modern 2BR Home | Patio & Pet-Friendly

Cozy Modern 2BR Home | Patio & Pet-Friendly
Mobile
10.0 out of 10, Exceptional, (2 reviews)
" Great location "
United States
Edwin G.
Cozy Modern 2BR Home | Patio & Pet-Friendly
Smart TV

5. Relax & Unwind at This Charming West Mobile Getaway! 2BR/2BA Guesthouse Retreat!

Relax & Unwind at This Charming West Mobile Getaway! 2BR/2BA Guesthouse Retreat!
Mobile
10.0 out of 10, Exceptional, (2 reviews)
"House was clean & just as listed. Host was very easy to communicate with. Would definitely recommend!!"
United States
Laurie H.
Relax & Unwind at This Charming West Mobile Getaway! 2BR/2BA Guesthouse Retreat!
Smart TV

6. Convenient 2BR Escape | Easy Walk to MOB

Convenient 2BR Escape | Easy Walk to MOB
Mobile
Convenient 2BR Escape | Easy Walk to MOB
Interior

7. Comfortable 2BR Escape | Chic & Cozy

Comfortable 2BR Escape | Chic & Cozy
Mobile
10.0 out of 10, Exceptional, (1 review)
"Joshua was so helpful and accommodating to our family for our stay. There are not many options other than hotels for the west mobile area so we were happy to find this one. The property was clean, comfortable and we enjoyed our stay. The neighborhood it is in felt safe and it was a great central location for us, though it is an older neighborhood with lower priced homes. Overall would give 5 stars for the actual home and owner. "
United States
Lisa M.
The price is AED 353
AED 1,206 total
includes taxes & fees
12 Aug - 13 Aug
Comfortable 2BR Escape | Chic & Cozy
Pool

8. Small Studio Condo -Private balcony -Free Parking

Small Studio Condo -Private balcony -Free Parking
Old Dauphin Way Historic District
9.4 out of 10, Exceptional, (117 reviews)
"Everything was wonderful, such a cute relaxing place."
United States
Cynthia W.
The price is AED 248
AED 574 total
includes taxes & fees
12 Aug - 13 Aug
Small Studio Condo -Private balcony -Free Parking
Outdoor dining

9. Cozy 2BR Retreat | Close to Top Mobile Attractions

Cozy 2BR Retreat | Close to Top Mobile Attractions
Mobile
7.8 out of 10, Good, (7 reviews)
"Great place central to area of Univ South Alabama All amenities where available Comfortable place So if of stay in the place again"
United States
Eduardo M.
Cozy 2BR Retreat | Close to Top Mobile Attractions
Exterior

10. King Bed Accessible|OYO Hotel Mobile

King Bed Accessible|OYO Hotel Mobile
Llanfair
10.0 out of 10, Exceptional, (107 reviews)
"Super convenient access to major roads but still felt peaceful and calm inside."
United States
Anonymous traveler
The price is AED 169
AED 220 total
includes taxes & fees
9 Sep - 10 Sep
King Bed Accessible|OYO Hotel Mobile
Interior

11. Large, comfortable home, great location, 4 bedroom, washer/dryer, pet friendly

Large, comfortable home, great location, 4 bedroom, washer/dryer, pet friendly
Mobile
6.0 out of 10, (2 reviews)
"This property was a WASTE OF TIME‼‼ Claim it was double book, yard was not presentable nor was the grass cut. The people that they choose to let stay broke the key box when they gave me the code for it."
United States
Gabriel S.
The price is AED 446
AED 1,182 total
includes taxes & fees
12 Aug - 13 Aug
Large, comfortable home, great location, 4 bedroom, washer/dryer, pet friendly
Property grounds

12. Private Charming Small Apartment

Private Charming Small Apartment
The Loop
9.6 out of 10, Exceptional, (64 reviews)
"Loved this apartment "
United States
Jenelle R.
The price is AED 275
AED 606 total
includes taxes & fees
12 Aug - 13 Aug
Private Charming Small Apartment
1 bedroom, WiFi, bed sheets

13. Fresh & Comfy Studio Apartment w/ Kitchenette

Fresh & Comfy Studio Apartment w/ Kitchenette
Old Dauphin Way Historic District
10.0 out of 10, Exceptional, (14 reviews)
"Nice and cozy. Perfect for a quick overnight stay!"
United States
Dan B.
The price is AED 268
AED 828 total
includes taxes & fees
12 Aug - 13 Aug
Fresh & Comfy Studio Apartment w/ Kitchenette
Interior

14. 1 Bedroom Apartment at Oak + Fountain - #4

1 Bedroom Apartment at Oak + Fountain - #4
Grand Bay
9.2 out of 10, Wonderful, (9 reviews)
"We planned for a weekend of peace and quiet nothingness and got exactly that very quiet ..and the dog loved it plenty of room to roam . We are already planning for the next trip back , thank you so much for the time at your establishment we had an amazing time , very cost friendly and pet friendly "
United States
fallen c.
1 Bedroom Apartment at Oak + Fountain - #4
Dining

15. Pet Friendly Midtown Mobile Condo

Pet Friendly Midtown Mobile Condo
Old Dauphin Way Historic District
8.8 out of 10, Excellent, (5 reviews)
"The unit was very cute and clean. Loved the bed. Great location"
United States
April
The price is AED 331
AED 953 total
includes taxes & fees
12 Aug - 13 Aug
Pet Friendly Midtown Mobile Condo
Smart TV, books

16. Midtown Guesthouse 15 Minute Walk to Downtown Entertainment

Midtown Guesthouse 15 Minute Walk to Downtown Entertainment
Old Dauphin Way Historic District
9.6 out of 10, Exceptional, (7 reviews)
"Very clean place. Easy to find. Very quiet neighborhood"
United States
Nicole T.
The price is AED 327
AED 592 total
includes taxes & fees
8 Sep - 9 Sep
Midtown Guesthouse 15 Minute Walk to Downtown Entertainment
Exterior detail

17. Charming studio in delightful Midtown Mobile with AC

Charming studio in delightful Midtown Mobile with AC
Mobile
10.0 out of 10, Exceptional, (3 reviews)
"Wonderful place to stay and so close to everything! "
United States
Brittany B.
The price is AED 251
AED 684 total
includes taxes & fees
15 Aug - 16 Aug
Charming studio in delightful Midtown Mobile with AC
Property grounds

18. King Bed |OYO Hotel Mobile

King Bed |OYO Hotel Mobile
Llanfair
10.0 out of 10, Exceptional, (72 reviews)
"Everything was spacious enough for us, great location near shopping too."
United States
Anonymous traveler
The price is AED 169
AED 219 total
includes taxes & fees
9 Sep - 10 Sep
King Bed |OYO Hotel Mobile
Interior

19. Stylish Home | Sleep 6 | Mid Town

Stylish Home | Sleep 6 | Mid Town
Dauphin Acres
9.0 out of 10, Wonderful, (7 reviews)
"Super clean"
United States
Juwannis
The price is AED 621
AED 911 total
includes taxes & fees
7 Sep - 8 Sep
Stylish Home | Sleep 6 | Mid Town
Exterior

20. 2 Full Beds|Mobile AL

2 Full Beds|Mobile AL
Llanfair
10.0 out of 10, Exceptional, (116 reviews)
"The pool is nice, and the variety of amenities was enjoyable."
United States
Anonymous traveler
The price is AED 184
AED 239 total
includes taxes & fees
9 Sep - 10 Sep
2 Full Beds|Mobile AL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Semmes Hotel Reviews

Drury Plaza Hotel Mobile

Drury Plaza Hotel Mobile

10/10 Excellent
"When I booked the room I read the reviews and they stated that this hotel was newly renovated. When I arrived, I was pleasantly surprised that it was not renovated but it was BRAND NEW! You could still smell the fresh paint and drywall when entering the lobby. Landscapers were still laying fresh Sod in the front. Hotel staff confirmed it was in fact a brand new hotel and had only been open for 3 weeks. Everything was brand spanking new. I loved it! The free breakfast was a FULL breakfast with every option you could think of. It was not just a continental breakfast. I also didn’t realize that free dinner was available nightly as well. That was also a nice surprise. Staff were polite and friendly every time we came in contact. I asked the supervisor Mel for a tour of a suite and he obliged with no questions asked. One afternoon Chris brewed me a fresh pot of coffee and popped some fresh popcorn which is also available 24/7 to guest. Just excellent hospitality all the way around. The bed was extremely comfortable and I loved the decor. It was tastefully done,neutral, and modern. This was my first time staying at a Drury hotel and it certainly won’t be my last."
RESHON 2-night trip
Posted 5 hours ago
Drury Plaza Hotel Mobile

Frequently asked questions

Are there vacation rentals in Semmes?

Yes, we offer vacation rentals close to popular sights in Semmes, or you can go with a more secluded option if you'd like a relaxing place to stay. Semmes is known for its shopping and restaurants.

What's the top vacation rental that Semmes has to offer?

Paula's Place - A property with large lot, fully gated for family fun: This vacation home rental outside of Semmes offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Semmes?

Choose from 6 Expedia vacation rentals in Semmes for a memorable vacation.

What’s there to see and do in Semmes?

While exploring the area, visit family-friendly sights like Gulf Coast Exploreum, or get outside and enjoy nature at Bienville Square. Other places in town to visit include Semmes City Hall and Semmes Library.

What’s a vacation rental in Semmes like?

Vacation rentals are privately owned properties where you can stay for short or long periods in Semmes. Vacation rentals offer amenities like WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can provide a sense of seclusion away from shared hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for a small group gathering.