A calm lake with mountains in the background.

Seneca Vacation Rentals

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Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for Seneca vacation rentals

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

1. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (116 reviews)
"My wife and I enjoyed our stay here. 10/10 experience."
United States
Winston
The price is AED 400
AED 602 total
includes taxes & fees
3 Nov - 4 Nov
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A living room with a large tiger mural, a fireplace, a sofa, and a coffee table.

2. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (23 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is AED 591
AED 1,351 total
includes taxes & fees
10 Nov - 11 Nov
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
A dining area with a wooden table and metal chairs, a ceiling fan, and a view of the outdoors through large windows.

3. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is AED 635
AED 1,350 total
includes taxes & fees
29 Oct - 30 Oct
Renovated 3BR near Lake Keowee & Clemson
A modern kitchen with a central island, wooden cabinets, and a built-in refrigerator.

4. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (13 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is AED 918
AED 1,523 total
includes taxes & fees
1 Nov - 2 Nov
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
A modern kitchen with white cabinetry, a central island, and a large window.

5. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is AED 932
AED 2,230 total
includes taxes & fees
29 Oct - 30 Oct
The Big Golf House- 10 miles to Clemson
A blue building with a wooden deck and two Adirondack chairs.

6. Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Extremely clean and well maintained, suited our needs for a long weekend just fine. We even cooked a couple of meals. We enjoyed using the fire pit for the first campfire of the season."
United States
Rebecca J.
The price is AED 459
AED 800 total
includes taxes & fees
29 Oct - 30 Oct
Cozy Clemson TIny House Cabin
A spacious living room with a high ceiling and a ceiling fan, a kitchen with modern appliances, and a dining area with a table and chairs.

7. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
The price is AED 397
AED 1,038 total
includes taxes & fees
1 Nov - 2 Nov
Peaceful 3-bedroom home 4 miles from Clemson.
A living room with a sofa, a coffee table, and a TV mounted on the wall.

8. Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Seneca
10.0 out of 10, Exceptional, (33 reviews)
"Great place to stay. The rooms were clean and we had plenty of space. Definitely would come back!"
United States
Brandon P.
The price is AED 441
AED 1,410 total
includes taxes & fees
17 Nov - 18 Nov
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
A bedroom with a wooden headboard, white bedding, and a dark blue throw blanket.

9. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (16 reviews)
"Perfect pet friendly spot to enjoy a weekend getaway! Quiet campground, homey vibe, and awesome location!"
United States
Josie G.
The price is AED 551
AED 739 total
includes taxes & fees
2 Nov - 3 Nov
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
A wooden deck with a railing overlooking a forested area during sunset.

10. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (19 reviews)
"Planning was super simple and the host is very responsive!"
United States
Trevor&Shaya Z.
The price is AED 944
AED 1,996 total
includes taxes & fees
19 Nov - 20 Nov
Waterfront 3br home on Lake Hartwell near Clemson
A wooden deck with a bench, table, and chairs, surrounded by a wooden railing and trees.

11. Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock

Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock
Seneca
9.6 out of 10, Exceptional, (13 reviews)
"We had a great time at Seneca Lake House. We would definitely stay here again. "
United States
Scott M.
The price is AED 1,157
AED 2,840 total
includes taxes & fees
29 Oct - 30 Oct
Lakefront Retreat l Near Clemson, Hot Tub, Game Room, Kayaks, Private Dock
A covered porch with wicker furniture, a wooden table, and a ceiling fan.

12. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (14 reviews)
"Everything was lovely."
United States
Allison C.
The price is AED 1,199
AED 2,552 total
includes taxes & fees
29 Oct - 30 Oct
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
A spacious living room with a sofa, chairs, a wooden coffee table, and a fireplace.

13. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.0 out of 10, Very good, (7 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is AED 603
AED 1,067 total
includes taxes & fees
29 Oct - 30 Oct
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
A compact living space with a sofa, a chair, a coffee table, and a kitchenette area.

14. Camping on Fancy-Perfect for small family getaway or couples retreat!

Camping on Fancy-Perfect for small family getaway or couples retreat!
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Perfect space for me and my husband to stay for family weekend at Clemson. Perfectly located, comfortable, and the hostess was incredibly kind and thoughtful.We will definitely be staying here again."
United States
Regina J.
The price is AED 496
AED 897 total
includes taxes & fees
17 Nov - 18 Nov
Camping on Fancy-Perfect for small family getaway or couples retreat!
A modern kitchen with wooden cabinets, stainless steel appliances, granite countertops, and pendant lighting.

15. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
2.0 out of 10, (1 review)
The price is AED 469
AED 1,567 total
includes taxes & fees
9 Nov - 10 Nov
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

16. Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is AED 327
AED 872 total
includes taxes & fees
29 Oct - 30 Oct
Clemson Memorabilia House
A compact, cozy interior with a dining area, a sofa, and a TV.

17. Tiny House - Slice of Heaven Walhalla

Tiny House - Slice of Heaven Walhalla
Walhalla
9.6 out of 10, Exceptional, (35 reviews)
"It was a nice stay "
United States
Anthony D.
The price is AED 496
AED 820 total
includes taxes & fees
29 Oct - 30 Oct
Tiny House - Slice of Heaven Walhalla
A white house with a sloped roof, surrounded by trees and a garden.

18. Clemson Game Day Cottage w/ Fire Pit

Clemson Game Day Cottage w/ Fire Pit
3.0 star property
Clemson
10.0 out of 10, Exceptional, (1 review)
The price is AED 665
AED 1,137 total
includes taxes & fees
29 Oct - 30 Oct
Clemson Game Day Cottage w/ Fire Pit
A lakeside deck with chairs and tables, overlooking a calm lake with boats and a dock.

19. Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option

Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
West Union
9.6 out of 10, Exceptional, (17 reviews)
"We had a great stay and all agreed it was an incredible week (ages 1-69.) The house was clean and well maintained, the amenities were terrific, very easy check in and check out, and we had great communication with the host. The lake view is beautiful and it is an easy walk down to the dock. One child said the place was better than Disney World."
United States
Helen B.
The price is AED 2,122
AED 4,742 total
includes taxes & fees
9 Nov - 10 Nov
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
A covered outdoor area with wicker furniture, a glass table, and ceiling fans.

20. Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina

Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina
Walhalla
9.8 out of 10, Exceptional, (16 reviews)
"Perfect home away from home. "
United States
Christine
The price is AED 606
AED 1,095 total
includes taxes & fees
29 Oct - 30 Oct
Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

8/10 Good
"Bit of a damp smell in our room which was on the first floor. Room was clean though. Staff were nice and very helpful. Further from Clemson than we imagined unfortunately."
David 2-night trip
Posted 1 day ago
Hampton Inn & Suites Seneca-Clemson Area

Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals in Seneca close to Blue Ridge Arts Center, or you can go with a more secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water: This highly rated vacation home rental in Seneca is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You can relax into your vacation with a garden and a selection of games. Some other homes for rent in Seneca include Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!.

How many vacation rentals are there in Seneca?

Choose from 217 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Lake Keowee and Lake Hartwell are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Oconee County Library Seneca Branch are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.