A calm lake with mountains in the background.

Seneca Vacation Rentals

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Check prices for these dates

In two weeks
7 Aug - 9 Aug
In two months
18 Sep - 20 Sep
In three months
16 Oct - 18 Oct
In four months
13 Nov - 15 Nov

Our top choices for Seneca vacation rentals

View from property

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (90 reviews)
"Cabin very cozy, pet friendly… great place to be disconnected for a couple days!! "
United States
LUIS EDUARDO
The price is AED 309
AED 501 total
includes taxes & fees
23 Aug - 24 Aug
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Exterior

Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Beautiful Tiny home! Quiet area where you can sit and enjoy nature, yet convenient to all of the needs you may have while escaping from the hustle & bustle of busy cities. Highly recommend for a quiet honey getaway that beats any hotel experience one could have! 10/10 "
United States
Charlotte C.
The price is AED 459
AED 800 total
includes taxes & fees
26 Jul - 27 Jul
Cozy Clemson TIny House Cabin
Smart TV, video games, table tennis

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Seneca
10.0 out of 10, Exceptional, (25 reviews)
"Very nice accommodations and great location for stay in Clemson. "
United States
Marisa G.
The price is AED 497
AED 1,436 total
includes taxes & fees
28 Jul - 29 Jul
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Property grounds

Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (14 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
The price is AED 900
AED 1,927 total
includes taxes & fees
24 Jul - 25 Jul
Waterfront 3br home on Lake Hartwell near Clemson
Smart TV, fireplace, books

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (20 reviews)
"Immaculate home very close to cute shops and restaurants. Perfect setup for our dog! "
United States
Joy B.
The price is AED 648
AED 1,421 total
includes taxes & fees
27 Jul - 28 Jul
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Coffee/tea maker, fridge, microwave, oven

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.6 out of 10, Exceptional, (10 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is AED 918
AED 1,515 total
includes taxes & fees
29 Jul - 30 Jul
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Coffee/tea maker, fridge, microwave, oven

Carolina Cottage Retreat-12 Minutes from Clemson University

Carolina Cottage Retreat-12 Minutes from Clemson University
Seneca
10.0 out of 10, Exceptional, (1 review)
"We were very pleased with our stay. Four bedrooms was perfect for us. The little coffee bar was an enjoyable perk!"
United States
Karen S.
The price is AED 740
AED 1,392 total
includes taxes & fees
3 Aug - 4 Aug
Carolina Cottage Retreat-12 Minutes from Clemson University
1 bedroom, WiFi, bed sheets

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (14 reviews)
"Very clean and comfortable - very close to Clemson and easy access. "
United States
Jim A.
The price is AED 551
AED 739 total
includes taxes & fees
27 Jul - 28 Jul
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Outdoor dining

South Cove Cottage 5 bedroom

South Cove Cottage 5 bedroom
Indian Oaks
9.6 out of 10, Exceptional, (11 reviews)
"Cozy house on the lake that was perfect for our family’s visit to the Clemson area. So many beds and room to spread out with a beautiful sunrise over the lake in the morning. "
United States
Richard M.
The price is AED 878
AED 2,501 total
includes taxes & fees
4 Aug - 5 Aug
South Cove Cottage 5 bedroom
Terrace/patio

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
The price is AED 672
AED 1,277 total
includes taxes & fees
23 Aug - 24 Aug
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Dining

Iroquois Crossroads - 10 min from Clemson & lakes

Iroquois Crossroads - 10 min from Clemson & lakes
Seneca
The price is AED 536
AED 1,369 total
includes taxes & fees
23 Aug - 24 Aug
Iroquois Crossroads - 10 min from Clemson & lakes
Microwave, oven, stovetop, dishwasher

The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is AED 1,238
AED 2,614 total
includes taxes & fees
18 Aug - 19 Aug
The Big Golf House- 10 miles to Clemson
Interior

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.4 out of 10, Exceptional, (10 reviews)
"Everything was lovely."
United States
Allison C.
The price is AED 1,199
AED 2,552 total
includes taxes & fees
26 Jul - 27 Jul
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
4 bedrooms, desk, iron/ironing board, WiFi (surcharge)

Johnsons Cove - Lakefront Retreat With EV Charger

Johnsons Cove - Lakefront Retreat With EV Charger
Seneca
10.0 out of 10, Exceptional, (1 review)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
The price is AED 1,212
AED 2,807 total
includes taxes & fees
3 Aug - 4 Aug
Johnsons Cove - Lakefront Retreat With EV Charger
Exterior

Tucker Farm Cottage on Century Farm

Tucker Farm Cottage on Century Farm
Seneca
10.0 out of 10, Exceptional, (36 reviews)
"Excellent stay, beautiful area!"
United States
Barbara W.
The price is AED 430
AED 1,409 total
includes taxes & fees
6 Aug - 7 Aug
Tucker Farm Cottage on Century Farm
Terrace/patio

Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
The price is AED 839
AED 1,607 total
includes taxes & fees
6 Aug - 7 Aug
Renovated 3BR near Lake Keowee & Clemson
Outdoor dining

Charming 2-bedroom home in Easley

Charming 2-bedroom home in Easley
Easley
9.2 out of 10, Wonderful, (5 reviews)
"We were in town visiting family friends, we enjoyed exploring downtown Greenville and all of the good local eats! The house was perfect, very charming! I loved the character. I would book again next time I’m in the area. "
United States
Maegan L.
The price is AED 496
AED 722 total
includes taxes & fees
5 Aug - 6 Aug
Charming 2-bedroom home in Easley
Dining

Peaceful 3-bedroom house with AC in charming Easley

Peaceful 3-bedroom house with AC in charming Easley
Easley
9.8 out of 10, Exceptional, (7 reviews)
"House was perfect for what we needed and the property manager was very accommodating and communicated well. Would definitely stay again if we’re back in the area. "
United States
Melanie D.
Peaceful 3-bedroom house with AC in charming Easley
Property grounds

Holly Trail Treehouse in Anderson w/WIFI, AC, Smart TV, Full Bath and washer

Holly Trail Treehouse in Anderson w/WIFI, AC, Smart TV, Full Bath and washer
Anderson
9.8 out of 10, Exceptional, (7 reviews)
"Really enjoyed our tree house stay. Renee had everything just right for us, including the beautiful weather!"
United States
Heather D.
The price is AED 909
AED 1,148 total
includes taxes & fees
27 Jul - 28 Jul
Holly Trail Treehouse in Anderson w/WIFI, AC, Smart TV, Full Bath and washer
Living area

Downtown Easley Home

Downtown Easley Home
Easley
8.0 out of 10, Very Good, (10 reviews)
"Comfortable beds, nice linens. Well stocked kitchen. Very clean!"
United States
Maura B.
The price is AED 364
AED 926 total
includes taxes & fees
17 Aug - 18 Aug
Downtown Easley Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"The only place we will stay!"
Alisha 3-night trip
Posted 2 days ago
Lakeside Lodge Clemson

Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals in Seneca close to Blue Ridge Arts Center, or you can go with a more secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.: This highly rated vacation home rental in Seneca is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 9 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Seneca include 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly! and Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson..

How many vacation rentals are there in Seneca?

Choose from 206 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Lake Keowee and Lake Hartwell are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Oconee County Library Seneca Branch are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.