A calm lake with mountains in the background.

Seneca Vacation Rentals

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Check prices for these dates

In two weeks
25 Sep - 27 Sep
In two months
6 Nov - 8 Nov
In three months
4 Dec - 6 Dec
In four months
1 Jan - 3 Jan

Our top choices for Seneca vacation rentals

View from property

1. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (102 reviews)
"Me and my family had a great time"
United States
Nirumol
The price is AED 340
AED 536 total
includes taxes & fees
14 Sep - 15 Sep
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Exterior

2. Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
10.0 out of 10, Exceptional, (3 reviews)
"The property was very clean and well maintained. The living space is large and the bathroom quite large as well. It was perfect for our needs. It is close to everything in the area. Jim was extremely helpful and super quick with his responses to our questions."
United States
Peter M.
The price is AED 459
AED 800 total
includes taxes & fees
15 Sep - 16 Sep
Cozy Clemson TIny House Cabin
Fridge, microwave, oven, stovetop

3. The Nest Above - Sparrow Suite

The Nest Above - Sparrow Suite
Downtown
10.0 out of 10, Exceptional, (1 review)
"Charming stay in the downtown area. Walking distance to restaurants and events on Ramcat Alley. We enjoyed our stay and wipp stay again on our next trip to the upstate."
United States
Deborah R.
The Nest Above - Sparrow Suite
Coffee/tea maker, fridge, microwave, oven

4. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (12 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is AED 826
AED 1,410 total
includes taxes & fees
15 Sep - 16 Sep
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Terrace/patio

5. Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
10.0 out of 10, Exceptional, (1 review)
"Beautiful home, no complaints."
United States
Brenda
The price is AED 585
AED 1,197 total
includes taxes & fees
13 Sep - 14 Sep
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Smart TV, fireplace, books

6. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (22 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is AED 629
AED 1,401 total
includes taxes & fees
13 Sep - 14 Sep
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Coffee/tea maker, fridge, microwave, oven

7. Carolina Cottage Retreat-12 Minutes from Clemson University

Carolina Cottage Retreat-12 Minutes from Clemson University
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"We were very pleased with our stay. Four bedrooms was perfect for us. The little coffee bar was an enjoyable perk!"
United States
Karen S.
The price is AED 612
AED 1,230 total
includes taxes & fees
13 Sep - 14 Sep
Carolina Cottage Retreat-12 Minutes from Clemson University
Property grounds

8. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (15 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
The price is AED 900
AED 1,935 total
includes taxes & fees
11 Sep - 12 Sep
Waterfront 3br home on Lake Hartwell near Clemson
1 bedroom, WiFi, bed sheets

9. Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (15 reviews)
"Perfect pet friendly spot to enjoy a weekend getaway! Quiet campground, homey vibe, and awesome location!"
United States
Josie G.
The price is AED 551
AED 739 total
includes taxes & fees
14 Sep - 15 Sep
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
3 bedrooms, WiFi (free)

10. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is AED 676
AED 1,404 total
includes taxes & fees
23 Sep - 24 Sep
Renovated 3BR near Lake Keowee & Clemson
Interior

11. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (11 reviews)
"Everything was lovely."
United States
Allison C.
The price is AED 1,199
AED 2,552 total
includes taxes & fees
13 Sep - 14 Sep
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
House (3 Bedrooms) | Interior

12. Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit

Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit
3.0 star property
Seneca
The price is AED 1,429
AED 2,881 total
includes taxes & fees
27 Sep - 28 Sep
Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit
Iron/ironing board, travel crib, WiFi, bed sheets

13. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
The price is AED 533
AED 1,442 total
includes taxes & fees
14 Sep - 15 Sep
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Coffee/tea maker, fridge, microwave, oven

14. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is AED 993
AED 2,308 total
includes taxes & fees
13 Sep - 14 Sep
The Big Golf House- 10 miles to Clemson
Smart TV

15. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.0 out of 10, Very Good, (7 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is AED 603
AED 1,067 total
includes taxes & fees
13 Sep - 14 Sep
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
4 bedrooms, desk, iron/ironing board, WiFi (surcharge)

16. Johnsons Cove - Lakefront Retreat With EV Charger

Johnsons Cove - Lakefront Retreat With EV Charger
Seneca
10.0 out of 10, Exceptional, (1 review)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
The price is AED 1,212
AED 2,807 total
includes taxes & fees
14 Sep - 15 Sep
Johnsons Cove - Lakefront Retreat With EV Charger
Dining

17. Iroquois Crossroads - 10 min from Clemson & lakes

Iroquois Crossroads - 10 min from Clemson & lakes
Seneca
The price is AED 496
AED 1,317 total
includes taxes & fees
23 Sep - 24 Sep
Iroquois Crossroads - 10 min from Clemson & lakes
Living area

18. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
The price is AED 397
AED 1,079 total
includes taxes & fees
15 Sep - 16 Sep
Peaceful 3-bedroom home 4 miles from Clemson.
Property grounds

19. Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson

Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Seneca
10.0 out of 10, Exceptional, (24 reviews)
"Great home and host"
United States
Anonymous traveler
The price is AED 2,571
AED 5,309 total
includes taxes & fees
13 Sep - 14 Sep
Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"Always amazing"
Charles 2-night trip
Posted 12 hours ago
Lakeside Lodge Clemson

Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals in Seneca close to Blue Ridge Arts Center, or you can go with a more secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!: This highly rated vacation home rental in Seneca is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade game room. Some other homes for rent in Seneca include New to VRBO! Big water views, private dock, pool table, 15 min Clemson! and Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock.

How many vacation rentals are there in Seneca?

Choose from 219 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Keowee Reservoir and Lake Keowee are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Lake Hartwell are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.