Panama City Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AEDĀ 5,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
A flagpole with the American flag, palm trees, and a sign that reads "Panama City Marina".

Downtown Panama City

1 out of top 10 points of interest in this area

While visiting Downtown Panama City, you might make a stop by sights like Panama City Marina and St. Andrews Bay.

Find hotels in Downtown Panama City

Find the Best Panama City Vacation Packages

Panama City Hotel Deals

La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
Fully refundableReserve now, pay when you stay
The price is AEDĀ 206 per night from Nov 29 to Nov 30
AEDĀ 206
AEDĀ 233 total
29 Nov - 30 Nov
includes taxes & fees
La Quinta Inn & Suites by Wyndham Panama City
Red Roof Inn Panama City

Red Roof Inn Panama City

2 out of 5
217 North US Hwy 231 Panama City FL
Fully refundableReserve now, pay when you stay
The price is AEDĀ 231 per night from Nov 15 to Nov 16
AEDĀ 231
AEDĀ 261 total
15 Nov - 16 Nov
includes taxes & fees
Red Roof Inn Panama City
Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
Fully refundableReserve now, pay when you stay
The price is AEDĀ 403 per night from Dec 1 to Dec 2
AEDĀ 403
AEDĀ 435 total
1 Dec - 2 Dec
includes taxes & fees
9.4/10 Exceptional! (897 reviews)
"Very clean property with great amenities and so close to the airport. The shuttle was fast and convenient and the staff were all so nice!"

Reviewed on 12 November 2026

Hilton Garden Inn Panama City Airport
See all 15,463 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Panama City attractions

A calm lake surrounded by lush greenery and a wooden bridge.

Harry Edward's Park

8.8/10 (3 reviews)
Explore the great outdoors at Cove Park, a lovely green space in Panama City. Wander the beautiful beaches and seaside in this family-friendly area.
See properties

Frequently asked questions

How much does a Panama City vacation package cost?
Offering great value package deals on Expedia, you'll be thrilled with how little a vacation to Panama City costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Panama City?
You can usually find lower prices and better availability in February, November and December. Take a look at our cheap Panama City vacation packages and you could score some great off-season discounts.
How to find the best Panama City package deals?
Use Expedia's filters to find some of the best Panama City package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Panama City package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as soon as possible.
Is it cheaper to book a Panama City vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging stays and flights separately. Better still, you can tailor your Panama City trip to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Panama City?
Land incredible bargains by booking your flights ahead of time with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for an impromptu Panama City trip.
How to plan a trip to Panama City?

  1. Choose when to get away: Check your calendar and pack your bags. Your preferred time of year and the type of activities on offer will also help you decide when to visit Panama City.
  2. Budget wisely: Besides the price of your hotel, you should factor in other expenses. These include transportation, flights and food. Also, put aside a little extra for unexpected costs that may arise during your trip to Panama City.
  3. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Panama City. Then, estimate how long you'll need at each, as well as any travel time.
  4. Bundle your hotel and flights: Awesome destination, check. Length of stay, check. All that's left now is to find a Panama City vacation package that brings all your bookings together.