Search Vacation Homes in Sikeston
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Our top choices for Sikeston vacation homes
1. Little Blue Cottage on Spanish
Little Blue Cottage on SpanishCape Girardeau
8.4 out of 10, Very good, (58 reviews)
"Great cute place. "
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
20 Sep - 21 Sep
2. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & CozyDexter
8.0 out of 10, Very good, (36 reviews)
"This was very convenient for our group - thank you!"
Kathryn T.
The price is AED 393
AED 796 total
includes taxes & fees
20 Sep - 21 Sep
3. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MODexter
The price is AED 477
AED 591 total
includes taxes & fees
20 Sep - 21 Sep
4. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Romantic Creekside Retreat | Fireplace | Deck | Pet FriendlyCape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
Sara C.
The price is AED 570
AED 834 total
includes taxes & fees
24 Sep - 25 Sep
5. The Little Cape Lofted Cottage | Creek & Nature
The Little Cape Lofted Cottage | Creek & NatureCape Girardeau
10.0 out of 10, Exceptional, (1 review)
"The tiny house was adorable, clean, and everything we expected. We can’t wait to stay in the others. We definitely recommend staying here. Lisa and Holly have done a wonderful job. Holly was great at getting back to me. Loved everything about our stay and the trip. Thank you so much"
Kim K.
The price is AED 532
AED 783 total
includes taxes & fees
19 Sep - 20 Sep
6. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer PoolCape Girardeau
8.8 out of 10, Excellent, (44 reviews)
"Will definitely book again! Great location, comfortable stay."
Pynktoria !.
The price is AED 658
AED 1,158 total
includes taxes & fees
21 Sep - 22 Sep
The price is AED 513
AED 763 total
includes taxes & fees
19 Sep - 20 Sep
8. Beautifully Renovated Farmhouse in Jackson, MO
Beautifully Renovated Farmhouse in Jackson, MOJackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
Sandy S.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find vacation rentals that suit your style
Cabins
Apartments
Save an average of 15% on thousands of hotels when you're signed in
Top Sikeston Hotel Reviews
Super 8 by Wyndham Sikeston/Miner Area
10/10 Excellent
