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Check prices for these dates

Next weekend
9 May - 11 May
In two weeks
16 May - 18 May
In one month
30 May - 1 Jun
In two months
27 Jun - 29 Jun

Compare 76 Vacation Homes in Sikeston with updated reviews, rates, and availability.

Serenity South -- Gardens, River-Views, and Refreshing Space
Fridge, microwave, oven, stovetop

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (130)
"Great place."
The price is AED 551
AED 889 total
includes taxes & fees
4 May - 5 May
Serenity South -- Gardens, River-Views, and Refreshing Space
Notting Hill Cottage
Exterior

Notting Hill Cottage

9.6 out of 10, Exceptional, (310)
"Got away with wife and kids (10 and 8). Perfect stay!"
Notting Hill Cottage
Beautiful location in the secluded woods
Outdoor dining

Beautiful location in the secluded woods

9.8 out of 10, Exceptional, (26)
"This property is wonderful for BBQs and having family in town. "
The price is AED 422
AED 680 total
includes taxes & fees
4 May - 5 May
Beautiful location in the secluded woods
* On the Wine Trail * Hot Tub * Wi-Fi *
TV

* On the Wine Trail * Hot Tub * Wi-Fi *

9.8 out of 10, Exceptional, (227)
"Thank you for your hospitality and quick assistance to any need. The apartment was cozy, clean and comfortable. We enjoy very much our stay and would love to be back for sure."
* On the Wine Trail * Hot Tub * Wi-Fi *
Wine Trail, Cozy Cabin plus hot tub
Terrace/patio

Wine Trail, Cozy Cabin plus hot tub

9.8 out of 10, Exceptional, (94)
"Loved our weekend away at this little gem! It was so quiet and the hot tub was so relaxing! We definitely plan on returning."
Wine Trail, Cozy Cabin plus hot tub
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Exterior detail

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

10.0 out of 10, Exceptional, (91)
"Centrally located to all the wineries. "
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
TV, fireplace, DVD player, books

Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

10.0 out of 10, Exceptional, (115)
"We enjoyed our stay! House was perfect for us, location was great for the planned visits. Great communication from host along with a nice welcome basket on the table. Looking forward to our return trip in April!!"
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
Brick Estate with pool in Quiet Carbondale Neighborhood
Terrace/patio

Brick Estate with pool in Quiet Carbondale Neighborhood

9.4 out of 10, Exceptional, (85)
"We enjoyed our stay here very much. The home is large yet cozy and located in a lovely quiet neighborhood. Perfect for visiting local family and friends!"
Brick Estate with pool in Quiet Carbondale Neighborhood
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Exterior

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.6 out of 10, Excellent, (29)
"Not bad but Hot tub was not accessible and the hotwater in the 2nd bedroom had no hot water."
The price is AED 731
AED 1,081 total
includes taxes & fees
5 May - 6 May
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Exterior

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.4 out of 10, Exceptional, (3)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
The price is AED 1,286
AED 1,962 total
includes taxes & fees
18 May - 19 May
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Dexter Homestead. Very Cozy & NEW Remodel !
Smart TV, fireplace, stereo

Dexter Homestead. Very Cozy & NEW Remodel !

8.0 out of 10, Very Good, (23)
"Plenty of room to move about. Quiet neighborhood. Host took care of all our needs."
The price is AED 364
AED 746 total
includes taxes & fees
5 May - 6 May
Dexter Homestead. Very Cozy & NEW Remodel !
Private lake, beach & hot tub, romantic getaway or family vaca
Private kitchen

Private lake, beach & hot tub, romantic getaway or family vaca

10.0 out of 10, Exceptional, (23)
"Love the peace. "
Private lake, beach & hot tub, romantic getaway or family vaca
'The Lakehouse' Lovely Wappapello Country Home!
Miscellaneous

'The Lakehouse' Lovely Wappapello Country Home!

9.8 out of 10, Exceptional, (16)
"Home was as describe and we enjoyed a memorable stay."
'The Lakehouse' Lovely Wappapello Country Home!
Charming 2-bedroom house in delightful Jackson with AC, WiFi
Fridge, microwave, oven, stovetop

Charming 2-bedroom house in delightful Jackson with AC, WiFi

10.0 out of 10, Exceptional, (4)
"Nice clean property second stay."
Charming 2-bedroom house in delightful Jackson with AC, WiFi
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Fridge, microwave, oven, stovetop

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (5)
"A large and comfortable house with cool historical details and just about everything you need to have a great, easy, smooth-running vacation. Great location for downtown exploring."
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Quaint, Beautiful Home next to SEMO and Hospital
Exterior

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (34)
"Great stay, great location! "
Quaint, Beautiful Home next to SEMO and Hospital
Welcome campers, hikers, fishermen, girls' weekend wine getaways!!
Property grounds

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

2.0 star property
10.0 out of 10, Exceptional, (10)
"Was a great property for our duck hunting trip to the area for four adults and four children. Great communication and friendly hosts! We love the place and we’ll be back for any future trips. Outside gazebo is fantastic as well."
The price is AED 735
AED 900 total
includes taxes & fees
6 May - 7 May
Welcome campers, hikers, fishermen, girls' weekend wine getaways!!
"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
Fridge, microwave, oven, stovetop

"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau

10.0 out of 10, Exceptional, (14)
"Chip, thanks for our stay in your beautiful house. We had a wonderful Christmas visit thanks to you."
"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
Embers of Murphysboro - 5 Star Cabin Sleeps up to 12 - GREAT AMMENITIES!
Bar (on property)

Embers of Murphysboro - 5 Star Cabin Sleeps up to 12 - GREAT AMMENITIES!

10.0 out of 10, Exceptional, (10)
"This was our 2nd time enjoying this home. We got to enjoy the pool this time. It was lovely! If you are looking for an expertly equipped, perfectly arranged, exquisitely comfortable home…THIS IS IT!"
Embers of Murphysboro - 5 Star Cabin Sleeps up to 12 - GREAT AMMENITIES!
StarView Vineyards Winery Retreat
Smart TV

StarView Vineyards Winery Retreat

10.0 out of 10, Exceptional, (33)
"The house was clean and nicely updated. There was plenty of room for us. The area is easily accessible to activities. "
StarView Vineyards Winery Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Sikeston

New cabin in the woods with private hot tub
Outdoor spa tub

New cabin in the woods with private hot tub

10.0 out of 10, Exceptional, (111)
"Very clean and cozy loved the hot tub!!"
New cabin in the woods with private hot tub
Beautiful location in the secluded woods
Outdoor dining

Beautiful location in the secluded woods

9.8 out of 10, Exceptional, (26)
"This property is wonderful for BBQs and having family in town. "
The price is AED 422
AED 680 total
includes taxes & fees
4 May - 5 May
Beautiful location in the secluded woods
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

10.0 out of 10, Exceptional, (380)
"We enjoyed our stay at this cozy cabin. Its in a quiet setting and accommodations were perfect for us!! "
The price is AED 430
AED 754 total
includes taxes & fees
4 May - 5 May
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.