South Fort Myers Vacations
Book a Hotel + Flight together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to AEDĀ 5,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Where to stay in South Fort Myers
Find the best South Fort Myers areas and neighborhoods for the activities you enjoy most. Learn more about South Fort Myers
Iona
While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.
South Fort Myers Hotel Deals
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is AEDĀ 757 per night from Jul 30 to Jul 31
AEDĀ 757
AEDĀ 1,028 total
30 Jul - 31 Jul
includes taxes & fees
9/10 Wonderful! (2,327 reviews)
"From the moment you check in, you are greeted with a smile and a margarita drink! Luggage is taken directly to your room. Beautiful, spacious, clean rooms. The pool area is gorgeous. All the bars and restaurants serve delicious food and drinks, with a smile. Love that if you stay, beach chairs and ..."
Reviewed on 16 July 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is AEDĀ 702 per night from Aug 11 to Aug 12
AEDĀ 702
AEDĀ 912 total
11 Aug - 12 Aug
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
"Hotel was pretty the yacht wasnāt running the lobby stuff was rude unknown charges at check in 600 plus no beach access big disappointment had to pay parking an toll fees to go to a beach told them we were there to celebrate my husbands birthday they done nothing special to help us celebrate just ..."
Reviewed on 16 July 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is AEDĀ 546 per night from Jul 19 to Jul 20
AEDĀ 546
AEDĀ 691 total
19 Jul - 20 Jul
includes taxes & fees
9/10 Wonderful! (1,747 reviews)
"We had a great vacation at the Lani Kai resort. The room was clean, comfortable, and spacious. The view from the room was great. We also took advantage of several amenities associated with the property. Specifically dolphin watching and parasailing. In addition to that, the food available on the ..."
Reviewed on 16 July 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.