A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Find Business Hotels in Southeast Iowa

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Iowa Business Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Southeast Iowa business-friendly hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.
A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.
A spacious lobby with a leather sofa, dining area, and a TV mounted on a stone wall.
A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.

1. Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison
Fort Madison
United States
Hunter
AED 349
AED 391 total
includes taxes & fees
26 Oct - 27 Oct
Cobblestone Inn & Suites - Fort Madison
A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.
A reception area with a stone wall, wooden reception desk, and a sign that reads "Quality".
A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.
An indoor swimming pool with clear water, surrounded by a white fence, and equipped with multiple entry points and seating areas.

2. Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61
Fort Madison
United States
Sharon
AED 298
AED 334 total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Fort Madison near Hwy 61
A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.
A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.
A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.
An indoor swimming pool with wooden walls and a balcony.

3. AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant
Mount Pleasant
United States
brian
AED 278
AED 311 total
includes taxes & fees
8 Nov - 9 Nov
AmericInn by Wyndham Mount Pleasant
An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.
A spa area with a hot tub, wooden ceiling, and tiled walls.
A multi-story hotel with a central entrance, a parking lot, and a clear sky.
A hotel room with a large bed, a desk with a computer, a chair, a window with curtains, and a view of the city.

4. Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North
Keokuk
United States
Bradley
AED 333
AED 373 total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Keokuk North
A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.
A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.
A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.
A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.

5. Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn
Mount Pleasant
United States
Paul
AED 286
AED 321 total
includes taxes & fees
8 Nov - 9 Nov
Best Western Mt. Pleasant Inn
A hotel room with two beds, a desk, a chair, and a large window.
A small, clean room with a kitchenette, a coffee machine, a microwave, and a TV mounted on the wall. There are two tables and chairs, and a window providing natural light.
A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.
A bathroom with a bathtub, toilet, and sink.

6. Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant
Mount Pleasant
United States
JOSE
AED 257
AED 288 total
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Mt Pleasant
An indoor swimming pool with a wooden ceiling and walls, a bench, and a rack of towels.
A brick building with a sign for Nauvoo Family Inn & Suites, featuring a traditional design with a tower and arched windows.
A hotel room with a bed, bedside lamps, a nightstand, a refrigerator, and a wooden headboard.
A guest registration area with a counter, informational signs, and various items on shelves.

7. The Inn at Old Nauvoo

The Inn at Old Nauvoo
Nauvoo
United States
Hollie
AED 449
AED 508 total
includes taxes & fees
1 Nov - 2 Nov
The Inn at Old Nauvoo
A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.
A modern hotel room with a large bed, two bedside tables with lamps, a small sofa, and a desk.
A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.
A reception desk with a "Welcome to the Hawk Eye State" sign, a digital kiosk, and a "Manager On Duty" sign.

8. Hampton Inn Keokuk

Hampton Inn Keokuk
Keokuk
United States
Kristopher
AED 372
AED 416 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Keokuk
A room with a large window, a sofa, and a chair.
A living room with a flat-screen TV on a white console, a grey sofa, and a framed picture on the wall.
A brick building with a balcony, a staircase, and a sign reading "Zions Mercantile".
A bedroom with two beds, a ceiling fan, a TV, and a dresser.

9. Nauvoo Temple House Hotel

Nauvoo Temple House Hotel
Nauvoo
United States
Miranda
AED 337
AED 396 total
includes taxes & fees
10 Nov - 11 Nov
Nauvoo Temple House Hotel
A room with a dark-colored sofa, a small wooden desk with a lamp, and a window with blinds.
A bedroom with a large bed, a bedside table with a lamp, a window with blinds, and a framed picture on the wall.
A living room with a sofa, a patterned armchair, a dining table with chairs, a kitchen area with wooden cabinets and a refrigerator, and a television on a stand.
A row of single-family homes with a well-maintained lawn and a tree in the foreground.

10. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
Nauvoo
United States
Renae
AED 460
AED 488 total
includes taxes & fees
21 Nov - 22 Nov
Nauvoo Vacation Villas & Condos
View all properties

Top Southeast Iowa Hotel Reviews

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk

10/10 Excellent
"Did not stay in motel except to sleep but it was perfect for that. Nice cool room and comfy bed"
Katie 2-night trip
Posted 10 hours ago
Baymont by Wyndham Keokuk
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

10/10 Excellent
"Great place to stay. Very convenient location, as there's a Walmart, Aldi's, dollar store and other shops in walking distance. Hotel was clean, had a heated pool and nice hot tub (good after a day of geode hunting). The staff was super friendly and helpful. I'd stay there again."
Heather 1-night trip
Posted 1 day ago
Quality Inn & Suites Keokuk North
Super 8 by Wyndham Burlington

Super 8 by Wyndham Burlington

8/10 Good
"Room was clean, staff was nice. Its a budget hotel. If you manage your expectations you will be fine."
Dustin 2-night trip
Posted 2 days ago
Super 8 by Wyndham Burlington