Southeastern Indiana Vacations

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Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

Find hotels in West Main Historic District

Find the Best Southeastern Indiana Vacation Packages

Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North
Radisson Hotel Louisville North
3 out of 5
505 Marriott Drive, Clarksville, IN
Fully refundableReserve now, pay when you stay
The price is AED 217 per night from Jun 18 to Jun 19
AED 217
AED 245 total
18 Jun - 19 Jun
includes taxes & fees
6.8/10 (2,071 reviews)
"Nice"

Reviewed on 16 May 2025

Radisson Hotel Louisville North
Sheraton Louisville Riverside by Marriott
Sheraton Louisville Riverside by Marriott
3.5 out of 5
700 West Riverside Drive, Jeffersonville, IN
Fully refundableReserve now, pay when you stay
The price is AED 342 per night from May 26 to May 27
AED 342
AED 386 total
26 May - 27 May
includes taxes & fees
8/10 Very Good! (1,008 reviews)
"Didnt have a mini fridge in room or even a microwave. Breakfast bar wasnt ready right at 630 like it should have been."

Reviewed on 10 May 2025

Sheraton Louisville Riverside by Marriott
Comfort Inn & Suites Clarksville - Louisville North
Comfort Inn & Suites Clarksville - Louisville North
2.5 out of 5
1485 Broadway St, Clarksville, IN
Fully refundableReserve now, pay when you stay
The price is AED 372 per night from Jun 1 to Jun 2
AED 372
AED 420 total
1 Jun - 2 Jun
includes taxes & fees
8.8/10 Excellent! (873 reviews)
"I liked the location and the room was sufficient. Did not like they didn’t change out towels and empty trash daily."

Reviewed on 12 May 2025

Comfort Inn & Suites Clarksville - Louisville North
See all 1,031 properties in Southeastern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southeastern Indiana

Louisville Slugger Museum showing interior views

Louisville Slugger Museum

4.5/5(606 reviews)

You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.

Louisville Slugger Museum
Helped celebrate the Belle of Louisville's 100th birthday with a cruise up the Ohio River.

Louisville Waterfront Park

4.5/5(301 reviews)

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its great live music.

Louisville Waterfront Park
Doc Crow's is perfect downtown spot for brisket and barbeque and has the tastiest drinks, especially the Man on Fire

Whiskey Row

Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

Whiskey Row