Photo by Southernmost Illinois Tourism Bureau
Find Resorts & Hotels with Spas in Southern Illinois, IL
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southern Illinois Resorts & Hotels with Spas
Our top choices for Southern Illinois hotels with a spa
9.4 out of 10, Exceptional, (484 reviews)
- Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
The price is AED 518
AED 575 total
includes taxes & fees
27 Jul - 28 Jul
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
- Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
The price is AED 353
AED 398 total
includes taxes & fees
9 Aug - 10 Aug
9.2 out of 10, Wonderful, (435 reviews)
- Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
The price is AED 205
AED 278 total
includes taxes & fees
29 Jul - 30 Jul
8.6 out of 10, Excellent, (1,020 reviews)
- Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is AED 542
AED 694 total
includes taxes & fees
9 Aug - 10 Aug
The price is AED 441
AED 489 total
includes taxes & fees
26 Jul - 27 Jul
9.0 out of 10, Wonderful, (1,992 reviews)
- Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is AED 528
AED 635 total
includes taxes & fees
23 Aug - 24 Aug
9.4 out of 10, Exceptional, (1,001 reviews)
- Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is AED 1,377
AED 1,611 total
includes taxes & fees
2 Aug - 3 Aug
9.2 out of 10, Wonderful, (575 reviews)
- Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
The price is AED 1,833
AED 2,140 total
includes taxes & fees
26 Jul - 27 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews
Quality Inn O'Fallon IL - St. Louis
8/10 Good
Explore a world of travel with Expedia
- Hotels near Dix Village Hall
- Hilton Hotels in Opdyke
- Cabin Rentals in Hoyleton
- 5 Star Hotels in Salem
- Farmstay in Southern Illinois
- Best Western Hotels in Mulkeytown
- 2 Star Hotels in Belle Rive
- Family Hotels in Okawville
- Pet-Friendly Hotels in West Frankfort
- Aimbridge Hospitality Hotels in Sesser
- Hotels with a Pool in Carlyle
- 3 Star Hotels in Keenes
- America's Best Inns Hotels in Ewing
- America's Best Inns Hotels in Dix
- Wyndham Hotels in Centralia
- Resorts in Mulkeytown
- 5 Star Hotels in Benton
- Cottages in Whittington
- Hotels with Free Parking in Marion
- Hotels near Pheasant Hollow Winery
- Aimbridge Hospitality Hotels in Centralia
- Best Western Hotels in Mount Vernon
- Wyndham Hotels in Keenes
- Independent Hotels in Sims
- 3 Star Hotels in McLeansboro
- Wyndham Hotels in Sesser
- Cabin Rentals in Ewing
- 5 Star Hotels in Bluford
- Wyndham Hotels in Benton
- Resorts & Hotels with Spas in Mount Vernon
- Historic Hotels in Carbondale
- Red Roof Inn Hotels in Centralia
- Benton Hotels
- Wyndham Hotels in Odin
- Condo Rentals in Benton
- 4 Star Hotels in Keenes
- Pet-Friendly Hotels in Carlyle
- Romantic Hotels in Marion
- Motels in Centralia
- 4 Star Hotels in Mount Vernon
- Wyndham Hotels in Opdyke
- Aimbridge Hospitality Hotels in Belle Rive
- Motel 6 Hotels in Opdyke
- Rv Parks in Christopher
- Aimbridge Hospitality Hotels in Ewing
- Marriott Hotels & Resorts in Centralia
- Cabin Rentals in Southern Illinois
- 3 Star Hotels in Hoyleton
- Motel 6 Hotels in Centralia
- Motel 6 Hotels in Odin
- Motels in Tamaroa
- Hotels with WiFi in Mount Vernon
- Red Roof Inn Hotels in Opdyke
- Romantic Hotels in Southern Illinois
- Hotels with Hot Tubs in Salem
- Golf Hotels in Flora
- Cabin Rentals in Mulkeytown
- Pet-Friendly Hotels in Carterville
- Opdyke Hotels
- Pet-Friendly Hotels in Whittington
- Marriott Hotels & Resorts in Christopher
- Apartments in Benton
- Lodges in Salem
- 3 Star Hotels in Sesser
- Independent Hotels in Salem
- Waltonville Hotels
- Family Hotels in Southern Illinois
- 3 Star Hotels in Opdyke
- 3 Star Hotels in Sims
- Hotels with Free Parking in Okawville
- Hotels with WiFi in Flora
- 2 Star Hotels in Keenes
- 4 Star Hotels in McLeansboro
- Pet-Friendly Hotels in Mount Vernon
- 5 Star Hotels in McLeansboro
- 4 Star Hotels in Sims
- Independent Hotels in Ewing
- Adventure Hotels in Mount Vernon
- Cabin Rentals in Salem
- Hotels with Free Parking in Albion
- Resorts & Hotels with Spas in Carbondale
- Marriott Hotels & Resorts in Ina
- Aimbridge Hospitality Hotels in Benton
- Motels in Odin
- 5 Star Hotels in Odin
- Hotels near I-57 Drag Strip
- Hilton Hotels in Centralia
- Flights from Hoyleton
- Flights from Benton
- Flights from Dix
- Flights from Mulkeytown
- Flights from Ewing
- Flights from Waltonville
- Flights from McLeansboro
- Flights from Southern Illinois
- Flights from Mount Vernon Outland
- Flights from Whittington
- Flights from Mount Vernon
- Flights to Mount Vernon
- Flights from Christopher