Find Resorts & Hotels with Spas in Southern Illinois, IL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Resorts & Hotels with Spas

This weekend
26 Jun - 28 Jun
Next weekend
3 Jul - 5 Jul

Our top choices for Southern Illinois hotels with a spa

Sauna, hot tub, body treatments, hot stone massages

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (469 reviews)
  • cleanliness
    Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
The price is AED 452
AED 502 total
includes taxes & fees
23 Jun - 24 Jun
Walker's Bluff Casino Resort
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
The price is AED 404
AED 456 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Reception

Arthur's Country Inn

Arthur's Country Inn
2.5 star property
Arthur
8.4 out of 10, Very Good, (143 reviews)
The price is AED 441
AED 489 total
includes taxes & fees
23 Jun - 24 Jun
Arthur's Country Inn
Front of property

1895 Washington Hotel

1895 Washington Hotel
3.0 star property
Paducah
9.2 out of 10, Wonderful, (427 reviews)
  • cleanliness
    Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
The price is AED 314
AED 425 total
includes taxes & fees
23 Jun - 24 Jun
1895 Washington Hotel
Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,008 reviews)
  • cleanliness
    Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is AED 571
AED 729 total
includes taxes & fees
6 Jul - 7 Jul
Ameristar Casino Resort and Spa
Restaurant

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,919 reviews)
  • cleanliness
    Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is AED 559
AED 672 total
includes taxes & fees
22 Jul - 23 Jul
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is AED 1,304
AED 1,525 total
includes taxes & fees
28 Jun - 29 Jun
Four Seasons Hotel St Louis
Reception

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (570 reviews)
  • cleanliness
    Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
The price is AED 1,833
AED 2,140 total
includes taxes & fees
28 Jun - 29 Jun
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included

Top Southern Illinois Hotel Reviews

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

8/10 Good
"Clean, quiet place to stay for the night. The breakfast was okay: it got our day going."
Virginia 1-night trip
Posted 2 hours ago
Super 8 by Wyndham Troy IL/St. Louis Area

Explore a world of travel with Expedia