Find Resorts & Hotels with Spas in Southern Illinois, IL

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Resorts & Hotels with Spas

Tonight
27 Oct - 28 Oct
Tomorrow
28 Oct - 29 Oct
This weekend
31 Oct - 2 Nov
Next weekend
7 Nov - 9 Nov

Top Southern Illinois Resorts & Hotels with Spas

Sauna, hot tub, body treatments, hot stone massages
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 star property
9.4 out of 10, Exceptional, (382)
"Great place!!"
United States
Jeff
Walker's Bluff Casino Resort
Property entrance
1895 Washington Hotel
1895 Washington Hotel
3.0 star property
9.2 out of 10, Wonderful, (380)
"James was wonderful and accommodated our unexpected evening when the rains made our overnight to Nashville turn into Paducah. We were exhausted but love d the relaxing space, jetted tub and front porch. He even made a hearty breakfast to get us to our next stop. "
United States
Jamie
1895 Washington Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
9.4 out of 10, Exceptional, (1001)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is AED 364
AED 410 total
includes taxes & fees
9 Nov - 10 Nov
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exclusive Room, 1 Queen Bed | Memory foam beds, desk, laptop workspace, iron/ironing board
Arthur's Country Inn
Arthur's Country Inn
2.5 star property
8.4 out of 10, Very Good, (130)
"We loved this Inn it was a unique experience in comparison to modern hotels but definitely a nice change. "
United States
Latasha
The price is AED 390
AED 433 total
includes taxes & fees
28 Oct - 29 Oct
Arthur's Country Inn
Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
8.4 out of 10, Very Good, (1010)
"Great place to stay.Will visit again."
United States
Shameka
The price is AED 684
AED 860 total
includes taxes & fees
28 Oct - 29 Oct
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 star property
9.0 out of 10, Wonderful, (1429)
"Great location for an event we attended."
United States
Catherine
The price is AED 526
AED 615 total
includes taxes & fees
2 Nov - 3 Nov
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
5.0 star property
9.4 out of 10, Exceptional, (1003)
"Beautiful stay at the four seasons! "
United States
Maria
The price is AED 1,561
AED 1,825 total
includes taxes & fees
31 Oct - 1 Nov
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (551)
"Service is exceptional!!!"
United States
Jorge
The price is AED 1,980
AED 2,311 total
includes taxes & fees
30 Oct - 31 Oct
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Friendly staff, wonderful accommodations."
Susan 1-night trip
Posted 3 days ago
Drury Plaza Hotel Mt. Vernon

Explore a world of travel with Expedia