Find Resorts & Hotels with Spas in Southern Illinois, IL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Resorts & Hotels with Spas

Our top choices for Southern Illinois hotels with a spa

Sauna, hot tub, body treatments, hot stone massages

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (468 reviews)
  • cleanliness
    Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
The price is AED 476
AED 528 total
includes taxes & fees
15 Jun - 16 Jun
Walker's Bluff Casino Resort
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
The price is AED 404
AED 456 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,013 reviews)
  • cleanliness
    Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is AED 585
AED 744 total
includes taxes & fees
1 Jul - 2 Jul
Ameristar Casino Resort and Spa
Reception

Arthur's Country Inn

Arthur's Country Inn
2.5 star property
Arthur
8.4 out of 10, Very Good, (142 reviews)
The price is AED 441
AED 489 total
includes taxes & fees
15 Jun - 16 Jun
Arthur's Country Inn
Front of property

1895 Washington Hotel

1895 Washington Hotel
3.0 star property
Paducah
9.2 out of 10, Wonderful, (426 reviews)
  • cleanliness
    Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
The price is AED 313
AED 424 total
includes taxes & fees
15 Jun - 16 Jun
1895 Washington Hotel
Restaurant

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,908 reviews)
  • cleanliness
    Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is AED 621
AED 744 total
includes taxes & fees
21 Jun - 22 Jun
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,007 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is AED 1,304
AED 1,525 total
includes taxes & fees
15 Jun - 16 Jun
Four Seasons Hotel St Louis
Reception

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (570 reviews)
  • cleanliness
    Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
The price is AED 1,833
AED 2,140 total
includes taxes & fees
21 Jun - 22 Jun
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Room was clean ,staff helpful, breakfast good"
Dale 1-night trip
Posted 10 hours ago
Drury Inn & Suites St. Louis Fairview Heights

Explore a world of travel with Expedia