A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Check prices for these dates

In two weeks
6 Nov - 8 Nov
In two months
18 Dec - 20 Dec
In three months
15 Jan - 17 Jan
In four months
12 Feb - 14 Feb

Our top choices for Southern Illinois vacation homes

A single-story house with a gabled roof, a front porch with a star decoration, and a number '213' on the wall.

1. Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64

Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
Ina
9.8 out of 10, Exceptional, (29 reviews)
"Very clean, host was very helpful, comfortable beds, fishing was great! Would stay again!"
United States
Contina S.
The price is AED 386
AED 814 total
includes taxes & fees
19 Nov - 20 Nov
Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
A wooden cabin entrance with a welcome sign, a small table with a lamp and flowers, and a woven mat on the floor.

2. Vintage Charmer on Main Street

Vintage Charmer on Main Street
Greenup
10.0 out of 10, Exceptional, (79 reviews)
"Great stay !"
United States
chris H.
Vintage Charmer on Main Street
A brick house with a white door, a mailbox, and a wooden porch.

3. Brickway Retreat

Brickway Retreat
Mattoon
9.8 out of 10, Exceptional, (53 reviews)
"Great place for a stay. Nice amenities and very clean. Would absolutely stay again"
United States
Kevin F.
The price is AED 404
AED 662 total
includes taxes & fees
26 Oct - 27 Oct
Brickway Retreat
A room with a bed, a sofa, a coffee table, a small table with a book, a mirror, and a window with a view of greenery.

4. Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.

Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.
Mount Vernon
10.0 out of 10, Exceptional, (4 reviews)
"Cute little place to stay for a nice weekend away."
United States
Kendra K.
The price is AED 354
AED 550 total
includes taxes & fees
27 Oct - 28 Oct
Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.
A rustic wooden room with a bed, a ceiling fan, and a wooden door.

5. Soothing bungalow in charming Joppa

Soothing bungalow in charming Joppa
Joppa
The price is AED 360
AED 782 total
includes taxes & fees
23 Oct - 24 Oct
Soothing bungalow in charming Joppa
A room with a wooden barn door, a dining area with blue chairs, and a washing machine in the background.

6. The Clark: Where Superheroes Sleep!

The Clark: Where Superheroes Sleep!
Metropolis
9.8 out of 10, Exceptional, (17 reviews)
"Great place to stay in Metropolis"
United States
Ashley T.
The price is AED 408
AED 607 total
includes taxes & fees
25 Oct - 26 Oct
The Clark: Where Superheroes Sleep!
A cozy living room with a wooden ceiling, a dark wood accent wall, a grey sofa with cushions, a white coffee table, and a small side table with a lamp.

7. Charming 1-bedroom house in terrific Harrisburg with AC, WiFi

Charming 1-bedroom house in terrific Harrisburg with AC, WiFi
Harrisburg
10.0 out of 10, Exceptional, (21 reviews)
"We stay here often perfect size and location. "
United States
Cher C.
The price is AED 377
AED 672 total
includes taxes & fees
26 Oct - 27 Oct
Charming 1-bedroom house in terrific Harrisburg with AC, WiFi
Interior

8. The Vault / Historical 1800s Bank 7min Off I-64. Downtown Main street

The Vault / Historical 1800s Bank 7min Off I-64. Downtown Main street
Fairfield
10.0 out of 10, Exceptional, (19 reviews)
"Just in town for a celebration. Very comfortable, clean and fun place to stay. "
United States
John D.
The price is AED 331
AED 428 total
includes taxes & fees
1 Nov - 2 Nov
The Vault / Historical 1800s Bank 7min Off I-64. Downtown Main street
A living room with a black leather sofa, a coffee table, and a floor lamp. There is a kitchen visible through an open doorway.

9. Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.

Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
Kevil
9.8 out of 10, Exceptional, (81 reviews)
"Very nice and quiet place to stay while we went to the AQS quilt show in Paducah. "
United States
Curt K.
The price is AED 430
AED 571 total
includes taxes & fees
24 Oct - 25 Oct
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
A bathroom with a toilet, sink, mirror, and shower curtain.

10. The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit
Murphysboro
The price is AED 347
AED 839 total
includes taxes & fees
26 Oct - 27 Oct
The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit
A rustic wooden console table with a mirror, a small plant, and a bird figurine.

11. The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Harrisburg
10.0 out of 10, Exceptional, (32 reviews)
"It's a great place to stay. Beautiful house. It's close to most restaurants and to Walmart."
United States
Jamie B.
The price is AED 331
AED 623 total
includes taxes & fees
22 Oct - 23 Oct
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
A cozy living room with a sofa, a small side table, and a dining area with a table and chairs. A kitchen is visible in the background.

12. Park View Place 4 Blocks From the World's Biggest

Park View Place 4 Blocks From the World's Biggest
Casey
9.8 out of 10, Exceptional, (45 reviews)
"Cozy and clean. Enjoyed our stay. Kids loved that the park was so close!"
United States
Angie R.
The price is AED 551
AED 876 total
includes taxes & fees
26 Oct - 27 Oct
Park View Place 4 Blocks From the World's Biggest
A spacious kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

13. Fish, boat, grill, chill, pets, relax

Fish, boat, grill, chill, pets, relax
Sullivan
9.4 out of 10, Exceptional, (72 reviews)
"It was excellent!"
United States
Samuel D S.
The price is AED 562
AED 1,047 total
includes taxes & fees
25 Oct - 26 Oct
Fish, boat, grill, chill, pets, relax
A two-story cabin with a balcony, surrounded by autumn foliage and a lake.

14. In the Country a Beautiful 2-bedroom house with its own private lake

In the Country a Beautiful 2-bedroom house with its own private lake
Waterloo
10.0 out of 10, Exceptional, (39 reviews)
"Wonderful place!"
United States
Tina S.
The price is AED 579
AED 925 total
includes taxes & fees
22 Oct - 23 Oct
In the Country a Beautiful 2-bedroom house with its own private lake
A house with a sloped roof and a satellite dish on the side.

15. Sweet Farm Stay

Sweet Farm Stay
Freeburg
9.8 out of 10, Exceptional, (53 reviews)
"Jill’s property was peaceful and quiet. We loved our stay. We absolutely loved, Dexter, the donkey and Willow and Marley, the cats. We had a very nice stay. I would not recommend counting the futon as a sleeping option. The bed in the master room was very comfortable, as well as the bed upstairs. Jill was excellent with communication and everything was well written out for check in and check out."
United States
Kellie
The price is AED 529
AED 638 total
includes taxes & fees
22 Oct - 23 Oct
Sweet Farm Stay
Interior

16. Soothing 1-bedroom house in lovely Madison perfect for relaxing stays

Soothing 1-bedroom house in lovely Madison perfect for relaxing stays
Madison
The price is AED 294
AED 389 total
includes taxes & fees
25 Oct - 26 Oct
Soothing 1-bedroom house in lovely Madison perfect for relaxing stays
A narrow stone pathway leading to a brick building with a sloped roof.

17. Peter Ray House

Peter Ray House
Maeystown
10.0 out of 10, Exceptional, (77 reviews)
"This house was incredible. Loved the history and ambience of the town. Peter was one of the nicest homes I’ve stayed in over the years. I would highly recommend it."
United States
Eric
The price is AED 496
AED 825 total
includes taxes & fees
22 Oct - 23 Oct
Peter Ray House
A brick building with a sign reading "1898 Guesthouse".

18. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (15 reviews)
"Cool renovated property that keeps that old fashioned charm. Spacious living with all the amenities you need for a vacation stay."
United States
Dylan
The price is AED 632
AED 1,211 total
includes taxes & fees
10 Nov - 11 Nov
Stunning 2 bedroom in town, close to Shawnee National Forest
A single-story house with a garage, a front porch, and a lawn.

19. All Things Marion- Themed 3br, Art Lovers Retreat

All Things Marion- Themed 3br, Art Lovers Retreat
Marion
9.8 out of 10, Exceptional, (16 reviews)
"We had a wonderful stay! The house was clean, cozy, and exactly what we needed for a weekend visiting family. Everything was comfortable and well-kept, and it really felt like a home away from home. We’d definitely stay again!"
United States
Anonymous traveler
The price is AED 635
AED 741 total
includes taxes & fees
27 Oct - 28 Oct
All Things Marion- Themed 3br, Art Lovers Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotel Reviews

Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

10/10 Excellent
"The front desk lady was helpful and nice. Room was clean and spacious. Breakfast runs low fast"
Emily 1-night trip
Posted 1 hour ago
Ramada by Wyndham Effingham

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