A forested valley with autumn foliage, a rocky cliff, and a sunset.

Search Vacation Homes in Southern Illinois

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
11 Sep - 13 Sep
In two months
23 Oct - 25 Oct
In three months
20 Nov - 22 Nov
In four months
18 Dec - 20 Dec

Our top choices for Southern Illinois vacation homes

Coffee/tea maker, fridge, microwave, oven

1. Pigs Ina Blanket - Minutes from Rend Lake and I-64/I-57

Pigs Ina Blanket - Minutes from Rend Lake and I-64/I-57
Ina
8.8 out of 10, Excellent, (38 reviews)
"Great place. Clean and comfortable!"
United States
Bill M.
The price is AED 393
AED 1,144 total
includes taxes & fees
7 Sep - 8 Sep
Pigs Ina Blanket - Minutes from Rend Lake and I-64/I-57
1 bedroom, iron/ironing board, WiFi (free), bed sheets

2. Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.

Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.
Mount Vernon
10.0 out of 10, Exceptional, (3 reviews)
"Beautiful property, great experience"
United States
Glenn
The price is AED 413
AED 613 total
includes taxes & fees
2 Sep - 3 Sep
Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.
Exterior

3. Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64

Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
Ina
9.8 out of 10, Exceptional, (28 reviews)
"Very clean, host was very helpful, comfortable beds, fishing was great! Would stay again!"
United States
Contina S.
The price is AED 408
AED 849 total
includes taxes & fees
15 Sep - 16 Sep
Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
Coffee/tea maker, fridge, microwave, oven

4. SunnyHill Cottage

SunnyHill Cottage
MOUNT VERNON
7.0 out of 10, Good, (4 reviews)
"Great house and host"
United States
Dawn W.
The price is AED 477
AED 1,024 total
includes taxes & fees
3 Sep - 4 Sep
SunnyHill Cottage
Interior

5. Historic Mt. Vernon House - Perfect family home, walking distance from downtown

Historic Mt. Vernon House - Perfect family home, walking distance from downtown
Mount Vernon
9.4 out of 10, Exceptional, (19 reviews)
"This is a great place to stay. My sons and I had a great time here."
United States
darius h.
The price is AED 540
AED 1,211 total
includes taxes & fees
9 Sep - 10 Sep
Historic Mt. Vernon House - Perfect family home, walking distance from downtown
Exterior detail

6. Romantic couples getaway in awesome Bluford with WiFi, Fireplace, and Game Room

Romantic couples getaway in awesome Bluford with WiFi, Fireplace, and Game Room
Bluford
10.0 out of 10, Exceptional, (7 reviews)
"The property was absolutely gorgeous, very clean, exactly as beautiful as the pictures in a quiet nice neighborhood. The host was incredible as well! Highly recommend!"
United States
Brianna W.
The price is AED 606
AED 954 total
includes taxes & fees
1 Sep - 2 Sep
Romantic couples getaway in awesome Bluford with WiFi, Fireplace, and Game Room
Dining

7. Beautiful home with pool in Wayne City

Beautiful home with pool in Wayne City
Wayne City
9.8 out of 10, Exceptional, (9 reviews)
"Great place to stay!"
United States
Kevin D.
The price is AED 485
AED 1,012 total
includes taxes & fees
8 Sep - 9 Sep
Beautiful home with pool in Wayne City
Coffee/tea maker, fridge, microwave, oven

8. Cozy country setting minutes from Rend Lake

Cozy country setting minutes from Rend Lake
Benton
10.0 out of 10, Exceptional, (44 reviews)
"Great place to stay very clean and comfortable "
United States
Thomas M.
The price is AED 413
AED 760 total
includes taxes & fees
31 Aug - 1 Sep
Cozy country setting minutes from Rend Lake
Exterior

9. Deluxe Suite - Bungalow overlooking on the Bluff!

Deluxe Suite - Bungalow overlooking on the Bluff!
Stone Church Precinct
9.2 out of 10, Wonderful, (46 reviews)
"Great peaceful location, loved sitting on the porch and watching the barges on the river.9"
United States
michele h.
The price is AED 270
AED 484 total
includes taxes & fees
31 Aug - 1 Sep
Deluxe Suite - Bungalow overlooking on the Bluff!
Property grounds

10. Newly renovated living room

Newly renovated living room
Benton
9.6 out of 10, Exceptional, (40 reviews)
"Very Nice good location"
United States
Gary A.
The price is AED 520
AED 1,360 total
includes taxes & fees
31 Aug - 1 Sep
Newly renovated living room
Terrace/patio

11. Lakehouse Resort Good Haven Dormer 4 Rend Lake

Lakehouse Resort Good Haven Dormer 4 Rend Lake
Benton
The price is AED 533
AED 860 total
includes taxes & fees
31 Aug - 1 Sep
Lakehouse Resort Good Haven Dormer 4 Rend Lake
Interior

12. The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping

The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Harrisburg
9.8 out of 10, Exceptional, (28 reviews)
"It's a great place to stay. Beautiful house. It's close to most restaurants and to Walmart."
United States
Jamie B.
The price is AED 331
AED 623 total
includes taxes & fees
31 Aug - 1 Sep
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
Smart TV, fireplace, books

13. Cozy home with the right amenities for your visit to our sweet town.

Cozy home with the right amenities for your visit to our sweet town.
Nashville
10.0 out of 10, Exceptional, (29 reviews)
"Great place to stay!"
United States
Theresa H.
The price is AED 533
AED 845 total
includes taxes & fees
6 Sep - 7 Sep
Cozy home with the right amenities for your visit to our sweet town.
Interior

14. Vintage Charmer on Main Street

Vintage Charmer on Main Street
Greenup
10.0 out of 10, Exceptional, (75 reviews)
"Great stay !"
United States
chris H.
The price is AED 324
AED 519 total
includes taxes & fees
31 Aug - 1 Sep
Vintage Charmer on Main Street
1 bedroom, iron/ironing board, WiFi, bed sheets

15. The Clark: Where Superheroes Sleep!

The Clark: Where Superheroes Sleep!
Metropolis
9.6 out of 10, Exceptional, (13 reviews)
The price is AED 367
AED 564 total
includes taxes & fees
31 Aug - 1 Sep
The Clark: Where Superheroes Sleep!
Terrace/patio

16. Superior Suite - Bungalow on the Bluff

Superior Suite - Bungalow on the Bluff
Stone Church Precinct
8.6 out of 10, Excellent, (14 reviews)
"Hosts were very nice and attentive. We’re going to stay here again—an underrated property and location. I have a lot of great pics to share. "
United States
Jay L.
The price is AED 424
AED 653 total
includes taxes & fees
15 Sep - 16 Sep
Superior Suite - Bungalow on the Bluff
Exterior

17. Secluded treehouse with indoor fireplace

Secluded treehouse with indoor fireplace
Makanda
10.0 out of 10, Exceptional, (26 reviews)
"The Treehouse was excellent. Derrick was a great host and even left some fresh roast coffee for us to sample. The proximity to state parks and the wine trail make a spot we would be happy to return to again!!"
United States
Josh J.
The price is AED 441
AED 708 total
includes taxes & fees
28 Sep - 29 Sep
Secluded treehouse with indoor fireplace
Dining

18. Comfy Clean & Cute

Comfy Clean & Cute
Marion
9.0 out of 10, Wonderful, (36 reviews)
"Absolutely wonderful!! Will definitely stay there again!! Everything we needed was fully stocked! Great location to all attractions! Host kelt us informed of what we needed! Thank you! "
United States
Brad W.
Comfy Clean & Cute
Smart TV

19. Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.

Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
Kevil
9.8 out of 10, Exceptional, (74 reviews)
"Very nice and quiet place to stay while we went to the AQS quilt show in Paducah. "
United States
Curt K.
The price is AED 430
AED 571 total
includes taxes & fees
31 Aug - 1 Sep
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
Interior

20. Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY

Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY
Equality
9.6 out of 10, Exceptional, (22 reviews)
"Great place to stay!"
United States
Alicia J.
The price is AED 477
AED 825 total
includes taxes & fees
31 Aug - 1 Sep
Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"L"
James 1-night trip
Posted 1 hour ago
Drury Plaza Hotel Mt. Vernon

Explore a world of travel with Expedia