A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Find Boutique Hotels in Southern Indiana

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Indiana Boutique Hotels

Tonight
6 Aug - 7 Aug
Tomorrow
7 Aug - 8 Aug
This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug

Our top choices for Southern Indiana boutique hotels

Front of property
Breakfast, lunch, dinner and brunch served
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe

1. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
nicolle
AED 559
AED 676 total
includes taxes & fees
3 Sep - 4 Sep
21c Museum Hotel Louisville
Lobby
Lobby
Interior
Interior

2. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
Anthony
AED 480
AED 565 total
includes taxes & fees
15 Aug - 16 Aug
The Brown Hotel
Interior entrance
Luxury Suite, 1 King Bed, Fireplace | Premium bedding, pillowtop beds, desk, iron/ironing board
Exterior
Front of property

3. Market Street Inn

Market Street Inn
Jeffersonville
United States
Anissa
AED 612
AED 692 total
includes taxes & fees
9 Aug - 10 Aug
Market Street Inn
View all properties

Top Southern Indiana Hotel Reviews