The Best Luxury Hotels in Southern Indiana from AED 474 in 2026 | Expedia

A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Luxury Hotels

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24 Oct - 25 Oct

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25 Oct - 26 Oct

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Our top choices for Southern Indiana luxury hotels

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, large windows, and classic furniture.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

1. The Brown Hotel

Downtown Louisville

Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.

AED 403

AED 474 total

includes taxes & fees

24 Nov - 25 Nov

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

2. 21c Museum Hotel Louisville

Downtown Louisville

Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.

AED 559

AED 676 total

includes taxes & fees

22 Nov - 23 Nov

A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

A long table set with white tablecloths, gold chargers, and clear glassware.

A covered porch with a brick wall, a wooden door, and a hanging light fixture.

3. The Pepin Mansion Historic B&B

New Albany

AED 356

AED 402 total

includes taxes & fees

26 Oct - 27 Oct

A bedroom with a large bed, a wooden floor, a white door, and a painting on the wall.

A cozy living room with a staircase, a sofa, a patterned rug, and a small table with a lamp.

A modern kitchen with a central island, wooden bar stools, a black refrigerator, and white cabinetry.

A living room with a dining area, white cabinetry, a flat-screen TV, and a large patterned rug.

4. Eclectic & Unique Historic Home

New Albany

AED 643

AED 1,781 total

includes taxes & fees

26 Oct - 27 Oct

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

5. Louisville Bourbon Inn

Old Louisville

Luxurious bourbon country retreat offers elegant rooms with Egyptian cotton sheets and champagne service just minutes from downtown.

AED 1,025

AED 1,189 total

includes taxes & fees

25 Oct - 26 Oct

A wooden deck with a table, chairs, and a lantern.

A large, historic house with a green roof, multiple chimneys, and a prominent front porch.

A cozy porch area with wicker furniture, a ceiling fan, string lights, and a welcome sign.

A grand staircase with dark wood railings and a chandelier.

6. Inn at Woodhaven

St. Matthews

AED 877

AED 1,018 total

includes taxes & fees

1 Nov - 2 Nov

Property grounds

A room with a foosball table, two ping pong tables, and a blue chair.

A modern kitchen with white cabinets, a wooden dining table, and a ceiling fan.

A modern kitchen with white cabinetry, a large island with bar stools, and a wood floor.

7. Creation Museum Hot Tub 4BR for 10

Burlington

AED 1,093

AED 2,153 total

includes taxes & fees

25 Oct - 26 Oct

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Top Southern Indiana Hotel Reviews

Hampton Inn Evansville/Airport

Hampton Inn Evansville/Airport

10/10 Excellent

"H"