Southern Indiana Vacations

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Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

Find hotels in West Main Historic District

Find the Best Southern Indiana Vacation Packages

Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
The price is AED 217 per night from Mar 12 to Mar 13
AED 217
AED 245 total
12 Mar - 13 Mar
includes taxes & fees
6.8/10 (2,771 reviews)
Everything in the room worked everything was clean and spotless the staff was very sweet especially Miss Jenny thank you Ms Jenny the pool was clean although it was a little cold but that was just because the ceiling fan was on and it's kind of an open pool but we enjoyed every moment. We will be ...

Reviewed on 1 February 2026

Radisson Hotel Louisville North
Bally’s Evansville Casino & Hotel

Bally’s Evansville Casino & Hotel

3 out of 5
421 NW Riverside Drive Evansville IN
Fully refundableReserve now, pay when you stay
The price is AED 237 per night from Feb 19 to Feb 20
AED 237
AED 357 total
19 Feb - 20 Feb
includes taxes & fees
7.6/10 Good! (1,269 reviews)
Excellent place nice rooms. Great environment. Thank you for everything

Reviewed on 2 February 2026

Bally’s Evansville Casino & Hotel
Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

3 out of 5
100 Cross Pointe Blvd Evansville IN
Fully refundableReserve now, pay when you stay
The price is AED 375 per night from Feb 15 to Feb 16
AED 375
AED 431 total
15 Feb - 16 Feb
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
As usual, our rooms at Drury Plaza have been clean and well appointed. As we needed a late check out our interaction with the front desk staff was most pleasant and they were helpful as always.

Reviewed on 3 February 2026

Drury Inn & Suites Evansville East
See all 1,638 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southern Indiana

Louisville Slugger Museum showing interior views

Louisville Slugger Museum

4.5/5(606 reviews)

You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.

Louisville Slugger Museum
Distillery whiskey wooden barrel container room factory in Kentucky, USA

Whiskey Row

Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

Whiskey Row
Walking The Big Four Bridge with Great Views

Louisville Waterfront Park

4.5/5(301 reviews)

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its acclaimed theater scene.

Louisville Waterfront Park

Frequently asked questions

How do I find cheap flights to Southern Indiana that have flexible change policies?
When it comes to flying these days, flexibility is key. That's why we have a "No change fee" search function to help you locate cheap, flexible tickets to Southern Indiana. It's to the left of your screen directly below the "Flexible change policies" heading.
Which airlines fly to Southern Indiana?
A good selection of airlines fly to airports in or near Southern Indiana. Your trip is only clicks away with these carriers:

  • Delta - 1,785 flights to or near Southern Indiana each month, including 1,256 flights to Cincinnati - Northern Kentucky Intl. Airport (CVG) and 442 to Louisville Intl. Airport (SDF) per month.
  • American Airlines - 1,743 flights to or near Southern Indiana each month, including 889 flights to Cincinnati - Northern Kentucky Intl. Airport (CVG) and 642 to Louisville Intl. Airport (SDF) per month.
  • United Airlines - 889 flights to or near Southern Indiana each month, including 481 flights to Cincinnati - Northern Kentucky Intl. Airport (CVG) and 408 to Louisville Intl. Airport (SDF) per month.

How can I find cheap tickets to Southern Indiana?
An effective strategy for walking away with cheap fares is to be flexible with your dates. Begin with searching for your flight to Southern Indiana, then click on the "flexible dates" box to see prices for nearby days. Another helpful hint? Book well in advance. To give you an idea of fares, was the best price for a flight to Southern Indiana in the last seven days.
How much is a flight to Southern Indiana?
You could have locked in a return flight to Southern Indiana from anywhere between and in the last seven days. For one-way journeys leaving from (), the lowest price during this time was .
What are the most popular airports to fly into in Southern Indiana?
Hop on a flight to Southern Indiana and you'll have a few airports to choose between. Here are some of the region's busiest:

  • Cincinnati - Northern Kentucky Intl. Airport (CVG) - 3,264 flights per month.
  • Louisville Intl. Airport (SDF) - 1,942 flights per month.
  • Evansville Regional Airport (EVV) - 325 flights per month.

When is the cheapest time to fly to Southern Indiana?
Jet off earlier in the week to land a bargain fare to Southern Indiana. Tuesday is routinely the most cost-effective day to fly, followed by Monday. Saturday often has the highest prices. This is because a lot of travelers like to begin their break on a weekend.
How much is a plane ticket to Southern Indiana?
In the last seven days, flights to Southern Indiana varied from to .
What months are the cheapest to book a flight to Southern Indiana?
To pick up a bargain flight to Southern Indiana, book sometime in February when airfares are at their lowest. When's the most costly? In the U.S, it's the month of December.
How long is a flight to Southern Indiana?
Whether or not you'll have time to watch your favorite TV series from start to finish depends on where you're traveling from. To give you a rough idea of what to expect, here are the average flight times for three popular domestic routes to Southern Indiana:

  • Chicago, IL (ORD-O'Hare Intl.) to Cincinnati - Northern Kentucky Intl. Airport (CVG) - 1 hour and 21 minutes
  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Cincinnati - Northern Kentucky Intl. Airport (CVG) - 1 hour and 25 minutes
  • Charlotte, NC (CLT-Charlotte-Douglas Intl.) to Cincinnati - Northern Kentucky Intl. Airport (CVG) - 1 hour and 34 minutes

What are the best things to do in Southern Indiana?

  • Bursting with culture and atmosphere, Louisville is the perfect place to start your Southern Indiana experience. Take a look at well-known attractions like Churchill Downs, hit the stores or wine and dine your way around some of this city's wonderful eateries. What you decide to do is up to you!
  • When working out what kind of clothes to pack for your getaway, bear in mind that Louisville has a humid subtropical climate. To give you a clearer picture of what to expect, check the weather before you depart.
  • Make Cincinnati the next place you stop at. It's about 145 kilometers to the northeast of Louisville and home to Mason Sports Park, one of the destination's top tourist sights.

What is the best time to go to Southern Indiana?
April, May and July are popular months to travel to Louisville, one of Southern Indiana's top cities. If you're ready for a summer break, plan your trip from June 20 onward and make the most of the warm, sunny days. Temperatures normally range from a pleasant 18ºC (64ºF) to a high of 30ºC (86ºF) during this time of year.