Southern Minnesota Vacations
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Where to stay in Southern Minnesota
Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
Downtown Rochester
2 out of top 10 points of interest in this area
4.5/5(250 area reviews)
If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.
Find the Best Southern Minnesota Vacation Packages
Southern Minnesota Hotel Deals
Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AED 542 per night from Jun 5 to Jun 6
AED 542
AED 623 total
includes taxes & fees
5 Jun - 6 Jun
8.2/10 Very Good! (1,378 reviews)
"Good customer service"
Reviewed on 2 June 2025
Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AED 408 per night from Jun 14 to Jun 15
AED 408
AED 469 total
includes taxes & fees
14 Jun - 15 Jun
9/10 Wonderful! (913 reviews)
"Great location for Mayo Clinic appointments. Hotel is modern, quiet, clean with a professional staff. Only negative is parking spots are tight."
Reviewed on 2 June 2025
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AED 508 per night from Jun 5 to Jun 6
AED 508
AED 585 total
includes taxes & fees
5 Jun - 6 Jun
7.6/10 Good! (1,349 reviews)
"Convenient to MAYO Clinic"
Reviewed on 28 May 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Southern Minnesota
Forestville Mystery Cave State Park
4.5/5(10 reviews)
Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.
Winona State University
4.5/5(94 reviews)
Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.
Lake Shetek State Park
4.5/5(5 reviews)
Commune with nature and explore the great outdoors at Lake Shetek State Park during your travels in The Lakes. Amble around the area's parks or experience its museums.