Find Business Hotels in Southwestern Virginia, VA

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southwestern Virginia Business Hotels

Top Southwestern Virginia Business Hotels

Front of property - evening/night
The Bolling Wilson Hotel

The Bolling Wilson Hotel

3.0 star property
Wytheville
9.6 out of 10, Exceptional, (774)
"Nice room and great staff"
United States
Greg
The price is AED 452
AED 560 total
includes taxes & fees
10 Dec - 11 Dec
The Bolling Wilson Hotel
Lobby
Comfort Inn & Suites Hillsville I-77

Comfort Inn & Suites Hillsville I-77

2.5 star property
Hillsville
9.2 out of 10, Wonderful, (1002)
"Great price, friendly staff and clean room!"
United States
Pearl
The price is AED 312
AED 357 total
includes taxes & fees
7 Jan - 8 January 2026
Comfort Inn & Suites Hillsville I-77
Front of property
General Francis Marion Hotel

General Francis Marion Hotel

4.0 star property
Marion
9.4 out of 10, Exceptional, (993)
"Great clean and safe place to stay! "
United States
Grant
The price is AED 395
AED 448 total
includes taxes & fees
10 Dec - 11 Dec
General Francis Marion Hotel
Room, 2 Queen Beds | Desk, laptop workspace, blackout drapes, iron/ironing board
Spark by Hilton Roanoke Civic Center

Spark by Hilton Roanoke Civic Center

2.5 star property
Gainsboro
9.0 out of 10, Wonderful, (126)
"The rooms were very clean and the staff was very nice! The breakfast is always a plus!"
United States
Katelyn
The price is AED 276
AED 313 total
includes taxes & fees
19 Dec - 20 Dec
Spark by Hilton Roanoke Civic Center
Lobby
The Highlander at Radford, Tapestry Collection by Hilton

The Highlander at Radford, Tapestry Collection by Hilton

3.5 star property
Radford
9.6 out of 10, Exceptional, (769)
"Perfect location when visiting Radford University. Clean rooms, very nice staff. "
United States
Edina
The price is AED 298
AED 350 total
includes taxes & fees
15 Dec - 16 Dec
The Highlander at Radford, Tapestry Collection by Hilton
Exterior
La Quinta Inn & Suites by Wyndham Roanoke Salem

La Quinta Inn & Suites by Wyndham Roanoke Salem

3.0 star property
Salem
9.0 out of 10, Wonderful, (1336)
"Great place to stay"
United States
Bruce
The price is AED 294
AED 333 total
includes taxes & fees
10 Dec - 11 Dec
La Quinta Inn & Suites by Wyndham Roanoke Salem
Deluxe Room | In-room safe, individually decorated, individually furnished, desk
Hotel Floyd

Hotel Floyd

2.0 star property
Floyd
9.6 out of 10, Exceptional, (493)
"Clean room, friendly staff, lovely artwork, short walk to restaurants. "
United States
Kathryn
The price is AED 404
AED 446 total
includes taxes & fees
1 Jan - 2 January 2026
Hotel Floyd
Suite, 2 Queen Beds, Non-Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Comfort Suites Abingdon I-81

Comfort Suites Abingdon I-81

2.5 star property
Abingdon
9.2 out of 10, Wonderful, (1002)
"Was a great place to stay. "
United States
Dan
The price is AED 347
AED 390 total
includes taxes & fees
3 Jan - 4 January 2026
Comfort Suites Abingdon I-81
Interior entrance
Travelodge by Wyndham Wytheville

Travelodge by Wyndham Wytheville

2.0 star property
Wytheville
8.2 out of 10, Very Good, (1273)
"Room was clean and the front desk clerk was very helpful,"
United States
Rosemary
The price is AED 239
AED 275 total
includes taxes & fees
10 Dec - 11 Dec
Travelodge by Wyndham Wytheville
Lounge
Jackson Park Inn, an Ascend Collection Hotel

Jackson Park Inn, an Ascend Collection Hotel

2.5 star property
Pulaski
9.4 out of 10, Exceptional, (713)
"Very clean. Beautiful rooms. Overall a great place to stay!"
United States
Martin
The price is AED 361
AED 401 total
includes taxes & fees
8 Jan - 9 January 2026
Jackson Park Inn, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southwestern Virginia Hotel Reviews

Country Inn & Suites by Radisson, Roanoke, VA

Country Inn & Suites by Radisson, Roanoke, VA

10/10 Excellent
"The clean suite the amenities and everything it had to offer"
jessica 3-night trip
Posted 3 days ago
Country Inn & Suites by Radisson, Roanoke, VA

Explore a world of travel with Expedia