Find Family Hotels in Southwestern Virginia, VA
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Our top choices for Southwestern Virginia family-friendly hotels
Spark by Hilton Wytheville Holston Rd I 81
Wytheville
8.6 out of 10, Excellent, (87)
"Great quick stay. Definitely recommend "
Alana
The price is AED 232
AED 268 total
includes taxes & fees
16 Dec - 17 Dec
The Bolling Wilson Hotel
Wytheville
9.6 out of 10, Exceptional, (774)
"Nice room and great staff"
Greg
The price is AED 452
AED 560 total
includes taxes & fees
11 Dec - 12 Dec
Comfort Inn & Suites Hillsville I-77
Hillsville
9.2 out of 10, Wonderful, (1002)
"Great price, friendly staff and clean room!"
Pearl
The price is AED 312
AED 357 total
includes taxes & fees
7 Jan - 8 January 2026
Sleep Inn Wytheville I-77 and I-81
Wytheville
9.2 out of 10, Wonderful, (1829)
"Great Hotel"
Kevin
The price is AED 312
AED 360 total
includes taxes & fees
1 Jan - 2 January 2026
General Francis Marion Hotel
Marion
9.4 out of 10, Exceptional, (993)
"Great clean and safe place to stay! "
Grant
The price is AED 395
AED 448 total
includes taxes & fees
10 Dec - 11 Dec
The Highlander at Radford, Tapestry Collection by Hilton
Radford
9.6 out of 10, Exceptional, (769)
"Perfect location when visiting Radford University. Clean rooms, very nice staff. "
Edina
The price is AED 298
AED 350 total
includes taxes & fees
15 Dec - 16 Dec
La Quinta Inn & Suites by Wyndham Roanoke Salem
Salem
9.0 out of 10, Wonderful, (1337)
"Great place to stay"
Bruce
The price is AED 294
AED 333 total
includes taxes & fees
10 Dec - 11 Dec
Comfort Suites Abingdon I-81
Abingdon
9.2 out of 10, Wonderful, (1000)
"Was a great place to stay. "
Dan
The price is AED 347
AED 390 total
includes taxes & fees
3 Jan - 4 January 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southwestern Virginia Hotel Reviews
Days Inn by Wyndham Roanoke/Hollins Near I-81
10/10 Excellent
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Hotels near popular Southwestern Virginia Attractions
- Hotels near Virginia Tech University
- Hotels near Carilion Roanoke Memorial Hospital
- Hotels near Lane Stadium
- Hotels near Berglund Center
- Hotels near Valley View Mall
- Hotels near Salem Civic Center
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- Hotels near Hollins University
Southwestern Virginia Hotels by Star Rating
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- Tru By Hilton Roanoke Hollins
- Hotel Roanoke & Conference Ctr, Curio Collection by Hilton
- Days Inn by Wyndham Roanoke/Hollins Near I-81
- Home2 Suites by Hilton Blacksburg - University
- Comfort Inn Blacksburg University Area
- Natural Bridge Hotel, Trademark Collection by Wyndham
- Country Inn & Suites by Radisson, Abingdon, VA
- Tru By Hilton Christiansburg
- Tru by Hilton Wytheville
- Hampton Inn & Suites Roanoke-Downtown
- Holiday Inn Express & Suites Roanoke – Civic Center by IHG
- Hyatt Place Roanoke Airport/Valley View Mall
- Home2 Suites by Hilton Roanoke, VA
- Travelodge by Wyndham Wytheville
- Red Roof Inn Wytheville
- The Lodge at Primland, Auberge Collection
- Comfort Inn & Suites Hillsville I-77
- Hilton Garden Inn Blacksburg University
- Hampton Inn Ft. Chiswell-Max Meadows
- Holiday Inn Express & Suites Blacksburg - University Area by IHG