A wooden bridge over a flowing river with moss-covered rocks.

St. James Vacation Rentals

Dates

November 2026

December 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for St. James vacation rentals

A living room with a sofa, armchair, coffee table, and a rug.

1. Pet-friendly 2BR with fenced yard

Saint James

Richie M.

AED 960 total

includes taxes & fees

11 Nov - 12 Nov

A compact kitchen with a coffee machine, a dining table with chairs, and a ceiling fan.

2. Pet-friendly 2BR cottage with garage

Saint James

Michael S.

AED 870 total

includes taxes & fees

23 Nov - 24 Nov

A spacious living area with a sofa, blue armchairs, a coffee table, and a rug.

3. The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James

Ellen

AED 823 total

includes taxes & fees

13 Nov - 14 Nov

A modern kitchen with dark cabinetry, a stainless steel sink, a microwave, and a stove.

4. Spacious 3BR near downtown St. James

Saint James

Billy A.

AED 1,014 total

includes taxes & fees

15 Nov - 16 Nov

A spacious living room with a ceiling fan, a herringbone-patterned floor, and a large window with sheer curtains.

5. Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit •

Saint James

Heather A.

AED 852 total

includes taxes & fees

11 Nov - 12 Nov

A modern kitchen with grey cabinets, a central island, and a dining area with brown chairs.

6. Get Cozy in the Country - The Cottage on Luca Hill

Saint James

K K.

AED 839 total

includes taxes & fees

11 Nov - 12 Nov

A kitchen with a central island, stainless steel appliances, and a blue-tiled backsplash.

7. 6BR Ozark Retreat on 10 Private Acres - Fire Pits, Game Room & Patio

Saint James

AED 2,741 total

includes taxes & fees

16 Nov - 17 Nov

A log cabin with a front porch, two windows, a door, and a small sign.

8. Peaceful and quiet cabin with keypad entry for convenient self check in.

Cuba

Rachel P.

AED 512 total

includes taxes & fees

1 Dec - 2 Dec

A wooden bench with a cushion labeled "Relax" on a porch overlooking a forest.

9. Relax in the Ozark woods at a quiet nature retreat with a private walking trail.

Cuba

Shelly

AED 522 total

includes taxes & fees

12 Nov - 13 Nov

A spacious living room with a grey leather sofa, a coffee table, and a large window with blue curtains.

10. Lakeside Retreat next to Conservation Area

Rolla

sharon m.

AED 1,038 total

includes taxes & fees

16 Nov - 17 Nov

A bedroom with a bed, bedside table, bench, and a window with curtains.

11. Simply Sweet 3 Bedroom Home - near MS&T & Fort Leonard Wood

Rolla

Liz H.

AED 786 total

includes taxes & fees

23 Nov - 24 Nov

A wooden bench with a large mirror, a white vase with flowers, a small wooden sculpture, and a globe.

12. Cozy Home on the edge of Rolla!

Rolla

Jesse C.

AED 641 total

includes taxes & fees

11 Nov - 12 Nov

A living room with a sectional sofa, a dining area with wooden chairs, and a kitchen with a brick backsplash.

13. The Green Acres Cottage - Charming 2 Bedroom near S&T and Acorn Trail in Rolla.

Rolla

Sarah T.

AED 845 total

includes taxes & fees

22 Nov - 23 Nov

A two-story house with a covered patio, a red door, and a wooden deck.

14. Get Back to Nature at Three Pine Cabin

Cuba

Randy T.

AED 740 total

includes taxes & fees

22 Nov - 23 Nov

A living room with a grey sofa, a coffee table, and a flat-screen TV. There are two potted plants and a clock on the wall.

15. Cozy 2-Bedroom House in Enchanting Rolla with AC Comfort

Rolla

Tracy D.

AED 841 total

includes taxes & fees

16 Nov - 17 Nov

A four-poster bed with a wooden finish, a dresser with multiple drawers, and a nightstand.

16. Spacious 4BR near Missouri S&T and downtown Rolla

Rolla

Ruth G.

AED 1,011 total

includes taxes & fees

15 Nov - 16 Nov

A kitchen with white cabinets, a microwave, a refrigerator, and a wooden dining table.

17. Cozy 2-bedroom house in Cuba, MO.

Cuba

Ann W.

AED 514 total

includes taxes & fees

1 Dec - 2 Dec

18. Farm View/Pool/FirePit/PS4/85"TV

Rolla

Elvina C.

AED 1,788 total

includes taxes & fees

29 Nov - 30 Nov

A covered outdoor seating area with a sofa and table, a door, and a view of a green landscape.

19. Unique and tranquil cabin getaway on Crooked Creek

Steelville

James T.

AED 1,174 total

includes taxes & fees

11 Nov - 12 Nov

A spacious loft with a wooden interior, a spiral staircase, a kitchen area, and a seating area with a coffee table.

20. Cabin at CM Cattleco

Newburg

Damaris M.

AED 881 total

includes taxes & fees

30 Nov - 1 Dec

View all properties

Find vacation rentals that suit your style

Top St. James Hotel Reviews

An indoor swimming pool with clear water, surrounded by lounge chairs and tables.

Greenlight Inn & Suites

St. James

10/10 Excellent

Property has recently been updated. Check-in was very easy and gal that checked us in was very sweet and kind. The air conditioning in the first room she gave us was not working so she immediately upgraded us to a suite and it was a lovely room, very clean, spacious and comfortable. They use Dove products in the bottles for soap, shampoo & conditioner which I was thrilled about. The Poole water was lukewarm and we were in the Poole for awhile. Had cable which was nice. Also recommended a nice...

Joyce

A living room with a dark sofa, a glass coffee table, a vase with flowers, a framed picture, a clock, and a welcome sign.

Finn's 66 Motel

St. James

10/10 Excellent

Anonymous traveler

A hotel lobby with a reception desk, seating area, and a green glass door.

Hampton Inn Rolla

Rolla

10/10 Excellent

Anonymous traveler

A pool area with a hot tub, seating, and a changing room.

Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG

Rolla

10/10 Excellent

Peggy

A hotel room with a bed, a flat-screen TV, two bedside lamps, a window with curtains, and a cityscape painting on the wall.

Super 8 by Wyndham Cuba

Cuba

10/10 Excellent

Tim

Owensville Motor Inn

Owensville

10/10 Excellent

Very pleasantly surprised. The staff were incredibly kind and accommodating. We have young children so cleanliness is very important to us. We can’t handle the slightest smell of smoke or mildew, so luckily that was not an issue here. The room smelled like fresh linen upon entering (not like the synthetic air fresheners. It was absolutely the linens themselves), and it was immaculate throughout. No frills and modest as far as decor but for any standards it was a nice, safe, clean, comfortable...

Jeremiah

An indoor swimming pool with clear blue water, surrounded by green chairs and potted plants.

Days Inn & Suites by Wyndham Cuba

Cuba

10/10 Excellent

Anonymous traveler

A hotel room with a large bed, a nightstand with a phone and alarm clock, a bedside table, a mirror, and a window with curtains.

Econo Lodge Rolla I-44 Exit 184 Near Missouri University of Science and Technology

Rolla

10/10 Excellent

Tony

A log cabin interior with a stone fireplace, leather furniture, and mounted animal heads on the walls.

Spacious Ozarks Family Home - Private Pool & Grill

Bourbon

10/10 Excellent

Ramon

Frequently Asked Questions

Can I find vacation rentals in St. James?

Yes, we give you a choice of vacation rentals close to popular points of interest in St. James, or you can select a secluded option if you'd like a relaxing place to stay. Our travelers say St. James has a good selection of wineries. Make sure you have time to check out the cafes while you're in the area.

What are some of the best vacation home rentals that St. James has to offer?

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James : Visitors give good reviews to this St. James vacation home rental, which offers a garden, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Some other homes for rent in St. James include The James Stay on Historic Route 66 • minutes away from Wineries & Restaurants and Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit • .

How many vacation rentals are there in St. James?

Choose from 19 Expedia vacation rentals in St. James for a memorable vacation.

What can I see and do in St. James?

Maramec Spring Park and Meramec River are a couple of scenic spots to enjoy the outdoors, whereas Rosati Winery Museum is one of the cultural attractions. Other places in town to visit include St. James Winery and Meramec Vineyards.

What are vacation rentals like in St. James?

Vacation rentals are privately owned properties you can book for several days or more in St. James. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a family trip.

St. James Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for St. James vacation rentals

1. Pet-friendly 2BR with fenced yard

2. Pet-friendly 2BR cottage with garage

3. The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

4. Spacious 3BR near downtown St. James

5. Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit •

6. Get Cozy in the Country - The Cottage on Luca Hill

7. 6BR Ozark Retreat on 10 Private Acres - Fire Pits, Game Room & Patio

8. Peaceful and quiet cabin with keypad entry for convenient self check in.

9. Relax in the Ozark woods at a quiet nature retreat with a private walking trail.

10. Lakeside Retreat next to Conservation Area

11. Simply Sweet 3 Bedroom Home - near MS&T & Fort Leonard Wood

12. Cozy Home on the edge of Rolla!

13. The Green Acres Cottage - Charming 2 Bedroom near S&T and Acorn Trail in Rolla.

14. Get Back to Nature at Three Pine Cabin

15. Cozy 2-Bedroom House in Enchanting Rolla with AC Comfort

16. Spacious 4BR near Missouri S&T and downtown Rolla

17. Cozy 2-bedroom house in Cuba, MO.

18. Farm View/Pool/FirePit/PS4/85"TV

19. Unique and tranquil cabin getaway on Crooked Creek

20. Cabin at CM Cattleco

Find vacation rentals that suit your style

Top St. James Hotel Reviews

Greenlight Inn & Suites

10/10 Excellent

Frequently Asked Questions

Can I find vacation rentals in St. James?

What are some of the best vacation home rentals that St. James has to offer?

How many vacation rentals are there in St. James?

What can I see and do in St. James?

What are vacation rentals like in St. James?