Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Find out about the history of St. Louis with a stop at Gateway Arch. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
Why not visit the native and exotic animals who live at St. Louis Zoo during your trip to St. Louis? Amble around the area's lush forest or attend a sporting event.
City Museum
You can spend an afternoon studying the exhibits at City Museum during your trip to St. Louis. Experience the area's fascinating museums and great live music.
Forest Park
After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
The stay was nice the staff were nice but there was hair and staining in the tub
Reviewed on 19 December 2025
AC Hotel St. Louis Clayton
The staff were very helpful while there! I recommend doing valet instead of self parking so you wouldn’t have to go through any hassle with finding a parking space but overall my stay was great. The bed was really comfy. I would definitely stay there again when visiting St Louis.
Reviewed on 25 November 2025
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Clean room, friendly staff.
Reviewed on 15 December 2025
Le Méridien St. Louis Clayton
The gym was amazing!
Reviewed on 21 December 2025
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Love this place.
Reviewed on 15 November 2025
Hyatt Regency St. Louis at The Arch
Walk in distance to restaurants, downtown and the gateway arch
Reviewed on 22 December 2025
Other neighborhoods around Clayton
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like St. Louis Black Repertory Company and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
Ladue
The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Southwest Garden
Though Southwest Garden might not have many top sights, you can venture to the surrounding area to see attractions like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Clayton, MO
- Places of interest
- Clayton Hotels by Star Rating
- More Hotel Options in Clayton
- Hotels in top St. Louis neighborhoods
- Clayton Hotels by Brand
- Chapel of St. Timothy And St. Titus
- St. Louis Union Station
- Busch Stadium
- Gateway Arch
- Dome at America’s Center
- Enterprise Center
- Washington University in St. Louis
- Barnes Jewish Hospital
- St. Louis Zoo
- America's Center Convention Complex
- City Museum
- Forest Park
- Ameristar Casino St. Charles
- Mississippi River
- Fox Theater
- St. Louis University
- Hollywood Casino Amphitheatre
- St Charles Convention Center
- Horseshoe St. Louis Casino
- Westport Plaza
- Hidden Valley Ski Resort
- Anheuser-Busch Brewery
- Route 66 State Park
- Saint Louis Galleria Mall
- Show Me
- Missouri Botanical Gardens and Arboretum
- Magic House - St. Louis Children's Museum
- St. Louis Aquarium at Union Station
- St. Louis Premium Outlets
- Grant's Farm
- Lindenwood University
- St. Louis Science Center
More Hotel Options in Clayton
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- Historic Hotels in Clayton
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- Hotels with Bars in Clayton
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- Hotels with a Pool in Clayton
- Hotels with an Indoor Pool in Clayton
- Luxury Hotels in Clayton
- Pet-friendly Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Romantic Hotels in Clayton
- Shopping Hotels in Clayton
