Clayton, MO

St. Louis

St. Louis Missouri
St. Louis Missouri
View over the Post-Dispatch Lake riffles at Forest Park (St. Louis) on a beautiful summer day.
The fire department bell

Popular places to visit


Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is AED 387 per night from Feb 28 to Mar 1
AED 387
AED 452 total
28 Feb - 1 Mar
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,083 reviews)
Staff always pleasant

Reviewed on 2 February 2026

Clayton Plaza Hotel & Extended Stay
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is AED 1,833 per night from Feb 15 to Feb 16
AED 1,833
AED 2,140 total
15 Feb - 16 Feb
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (557 reviews)
Excellent hotel with various restaurants and expansive lobby area.. staff very attentive.

Reviewed on 6 February 2026

The Ritz-Carlton, St. Louis
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
The price is AED 434 per night from Feb 26 to Feb 27
AED 434
AED 511 total
26 Feb - 27 Feb
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (934 reviews)
Pleasant and professional staff. Updated property and was incredibly clean!

Reviewed on 29 January 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is AED 511 per night from Feb 22 to Feb 23
AED 511
AED 596 total
22 Feb - 23 Feb
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (241 reviews)
My room was spotless and very well put together.

Reviewed on 9 January 2026

AC Hotel St. Louis Clayton
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is AED 493 per night from Feb 22 to Feb 23
AED 493
AED 594 total
22 Feb - 23 Feb
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,594 reviews)
Everything was great i can’t wait to stay again

Reviewed on 6 February 2026

21C Museum Hotel St Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
The price is AED 331 per night from Feb 12 to Feb 13
AED 331
AED 389 total
12 Feb - 13 Feb
includes taxes & fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,806 reviews)
Clean rooms, comfy beds and convenient shuttle to the airport. The breakfast was good with plenty of options (both hot and cold) and plenty of food. The staff was very friendly and helpful.

Reviewed on 4 February 2026

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Clayton

New Loop Trolley at Delmar St Louis

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
The bandstand located in Forest Park, St. Louis, Missouri.

Dogtown

If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.

Dogtown
View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois

Ladue

The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.

Ladue
Visitor Center in Forest Park in St. Louis

The Hill

If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Hill
Southwest Garden

Southwest Garden

4.5/5(3 area reviews)

Though Southwest Garden might not have many top sights, you can venture to the surrounding area to see attractions like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Southwest Garden
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End


Clayton, MO

Choose two or more items and save on your trip: